Objective To explore the impact of curcumin on antistreptolysin“O”(ASO)and interleukin 8 (IL-8)level changes in serum of psoriatic mice model induced by phorbol ester(TPA).Methods 132 SCID mice were selected and divided into three groups.43 mice in normal group, 46 mice in model group,and 43 mice in intervention group.The mice of model group and intervention group were set up psoriasis model induced by TPA. Mice of the three groups were bred in the same environment,curcumin was injected in the intervention group mice,0.02 g/100 g,once a day,two weeks for a period of treatment.ASO and IL-8 level were compared amorg the three groups of mice after treatment.Results Before the treatment,compared with the normal group,positive rate of ASO in model group and intervention group increased significantly,and the difference was statistically significant (P<0.05 );after treatment,the level of intervention group was significantly lower than model group,and the difference was statistically significant (P<0.05 );before the treatment,compared with the normal group,IL-8 level in intervention group and model group increased significantly,and the difference was statistically significant (P<0.05 );after treatment,level of the intervention group was significantly lower than model group,and the difference was statistically significant (P<0.05).Conclusion Curcumin could effectively reduce ASO and IL-8 level in serum of psoriatic mice model, improve the clinical symptoms of psoriasis mice,it is an effective drug for treatment of psoriasis.

Intestine is one of the fastest cellular renewal tissues and organs in the body cells,and intestinal mucosal epithelial cells keep self-renewal constantly all the life.Its effect relys on stem cells continued proliferation,differentiation and replaces the outer terminal differentiated cells.Under the stimulation after injury,the repairment of stem cells is initiated,the proliferation and differentiation of intestinal stem cells are stimulated throughout molecular mechanisms.Studys found that intestinal stem cells involve in the repairment of the gut during stress,trauma,anoxia,radioactive damage,inflammatory bowel disease and short bowel syndrome.In this paper,we briefly overviewed the definition,location,and differentiated regulation stem cells,and influence factors in the intestinal repairment.

One of the human GM-CSF cDNA was successfully isolated with a new screening method. Up 1/170 of positive rate was reached. The COS-7 cells were transfected with the cDNA clone and the resulting supernants contained colony-stimulatory activities. Human GM-CSF cDNA was also subcloned into a expression plasmid pKPL-2D and the unfused recombinant human GM-CSF was expressed in E. coli. The expressed products could maintain in vitro the growth of a cell line BMU- 2 and stimulate its colony formation. In addition, it could increase the colony formation of bone marrow cells from the patients with acute non-lymphatic leukemia (ANLL).

Objective To establish the optimum preparation process for Yinxingye Dropping Pills. Methods The preparation conditions, such as different kinds of primary substance, cooling agent, the proportion between the extracts and primary substance, etc, were studied with L9 (34) orthogonal design. Results At the following conditions could the best was 30 d/min, dropping distance was 8cm, and cooling temperature was 10℃. Conclusion This preparation process was suitable for both laboratory test and industrial production for Yinxingye Dropping Pills.

Objective To establish the optimal extraction technology for Yishen Jiangu Granules.Methods The orthogonal test was employed for selecting the optimum of extraction technology. The investigation factors were the consumption of water, the times and time of extraction. The extraction technology of Yishen Jiangu Granules was screened by the transfer rate of icariin in herb epimedii and yield of extraction.Results The best extraction condition was as follows:10 times of water, extracted for 3 times , each time was 3 h,2 h and 2 h. Conclusion This extracting technology for Yishen Jiangu Granule was objective, feasible, stable,reasonable and with good reproducibility.

Child ; Evidence-Based Medicine ; Humans ; Kidney Diseases ; therapy

The study intended to evaluate the combined examination of transient flash visual evoked potential (T-FVEP) and steady-state flash visual evoked potential (SS-FVEP) in diagnosis of optic neuropathy and macular disease. T-FVEP and SS-FVEP were examined in 22 cases (29 eyes) with optic neuropathy, 8 cases (9 eyes) with macular disease and 32 cases (32 eyes) of controls. The positive rates of T-FVEP and SS-FVEP in diagnosis of optic neuropathy were 83% and 100% respectively; that of combined examination was 100%. The positive rates of T-FVEP and SS-FVEP in diagnosis of macular disease were 5/9 and 7/9, and that of combined examination was 8/9. The positive rates of combined examination of T-FVEP and SS-FVEP in diagnosis of optic neuropathy and macular disease are higher than that of T-FVEP and SS-FVEP alone, and should be used routinely in the diagnosis of visual pathway disease.

For a valid control of the finance management, the management system is developed again aiming at finance related control links and key control points. In this way, the control is rigorous and integral with simple procedures for check and examination. The key control point is set oriented to note management. Real-time operation is controlled. Post output processing is controlled. With business income and business expenditure as the main line, the control process of the related links are built up. Computer maintenance system is controlled.

Objective:To supply the rescue and treatment to stroke patients in the first time by the building of green information network platform. Methods:Build green information network platform, which taking the UCC as the entrance, using the IP green alarm bell system as the start point, mixing the Hospital Information System, Picture Archiving and Communication Systems, Laboratory Information System, and office automation system together. The platform attains the features of systems interflowed, equipment connected, information shared and data sending at once. These features make the sharing of patient’s information accurate and faster, so that the emergency rescue process is optimized. Results:In the past, it might cost about 20 minutes between the patients’ arriving and the rescue’s starting. When the green information network platform was used, the time was reduced to about 3 minutes. Conclusion: The green information network platform can optimize the process of emergency rescue effectively.