Advanced non-small cell lung cancer(NSCLC)accounts for all NSCLC 45% . In recent years,chemotherapy combined with radiotherapy has become a new standard for NSCLC. On NSCLC radiothera-py and chemotherapy(CRCT),radiation total dose,fractionation method,different chemotherapy combined with radiotherapy have many details in the efficiency and toxicity tolerance,which are still in the exploration.

Objective: The effects of two fat substitutes, sucrose polyester(SPE) and triglyceride of short fatty acids(TRIS)on lipid metabolism in rats were studied. Methods: Diets containing either SPE or TRIS were fed to rats for 30d. Male Wistar rats were allowed free access to one of three diets: a control diet containing 20% corn oil, SPE group diet containing 10% SPE and 10% corn oil, TRIS group diet containing 20% TRIS. Plasma glucose, TG, TC, HDL C, LDL C, ApoA I, ApoB were analysed. Results: Dietary fat substitutes lowered total energy consumption and body weight 8.1%?4.1%and 12.3% ?16.0% respectively. Two fat substitutes lowered plasma glucose, TG, TC, LDL C, VLDL C, ApoB level and increased HDL C and ApoA I level. TRIS could decrease TC/HDL C, LDL C/HDL C, ApoB/ApoA I more significantly than SPE. Conclusion: TRIS and SPE have the potential benefits on lipid metabolism and energy intake control in rats, TRIS is more efficient than SPE.

Phyllosphere and epiphytes have attracted significant interest of more and more researchers by their unique biological characteristics. Progress of research on phyllosphere and epiphytes was summarized in this paper, and the special emphasis was put on the characteristic of phyllosphere, microbial communities, invasion and the location of bacteria on leaf surfaces. Some ideas for further studies on phyllosphere microbes were also proposed.

Objective To observe the effect of new moist dressings on pressure ulcers after spinal cord injury. Methods 58 spinal cord injured patients complicated with pressure ulcers were divided into observation group (n=29) and control group (n=29). The observation group accepted moist dressings, while the control group accepted routine dry dressings, TDP and ultraviolet irradiation. The incidence of im provement were recorded 2 weeks after treatment, and the time of healing were compared. Results 11 cases cured, 17 cases relieved in the observation group, and it was 5 and 18 cases in the control group, respectively (P<0.05). It spent (26.69±16.48) days to cure in the observa tion group, and (38.24±22.47) days in the control group (P<0.05). Conclusion The moist therapy may promote the cure of pressure ulcers af ter spinal cord injury, and shorten the time of cure.

Interferon ( IFN) plays an essential role in antiviral infection.Interferons are divided into different categories according to their structure and function.People have attached increasing importance to TypeⅠinterferon( IFN-Ⅰ) in light of its unusual antiviral mechanism.This review is intended to shed light on IFN-Ⅰ,including its antiviral function,signal pathway and regulation.

China ; epidemiology ; Hearing Loss, Sudden ; diagnosis ; epidemiology ; Humans

Objective To observe changes of apoptosis and Caspase-12 expression in hippocampus of the rat model of posttraumatic stress disorder ( PTSD ) .Methods Single prolonged stress ( SPS ) was used to duplicate a rat model of PTSD.Male Wistar rats were randomly divided into 1, 4, 7 days groups after exposure to SPS and a normal control group.Transmission electron microscopy was used to observe morphologic changes of the hippocampus neurons .The expression of Caspase-12 was detected by immunohistochemistry , Western blotting and RT-PCR.Results After SPS, the hippocampus neurons had characteristic morphologic changes of apoptosis , and the expression of Caspase-12 reached the peak at SPS 4d.Conclusion PTSD activates the ERS-mediated apoptosis in hippocampus via Caspase-12, which may be a pathophysiology base of the atrophy of the hippocampus in PTSD .

Objective To assess the value of MR Grs3d sequences in evaluating knee meniscal injury and complication with low field MR unit.Methods MR imaging of knee was performed in 73 patients with sagittal Grs3d,sagittal SE T1WI + PDWI.The efficiency of both sagittal Grs3d and sagittal SE T1WI+PDWI in showing knee meniscal injury and complications were evaluated comparatively.Results The rate in showing meniscal injury and complications with Grs3d sequence was higer in comparison with SE T1WI+PDWI and was of significantly different(P