Child ; Chronic Disease ; Humans ; Kidney Diseases ; therapy ; Kidney Failure, Chronic ; therapy ; Nutritional Support ; Renal Insufficiency, Chronic ; therapy

Objective To compare the clinical results of endodontic mandibular first molar by different restoration methods.Methods From January 2011 to February 2013,96 patients in our hospital dental visits with 110 defective teeth who accepted the dental restoration were randomly selected in this clinical research.The repairing of defective teeth were divided into 3 groups randomly:36 were fabricated with CAD/CAM zirconia all -ceramic crowns,35 were CAD/CAMzirconia all -ceramic onlays,39 were direct filling and repairing with composite resins. The clinical effects of 3 groups were evaluated and compared at baseline,and 1,6,12 months after restoration using modified USPHS criteria.The results were analyzed statistically by SPSS 13.0.Results It was not found that 110 defective teeth were debonded at 12 months after restoration.There were significant differences in assessment results of secondary caries,marginal fitness,appearance and color matching at 12 months after restoration by different restoration methods (χ2 =6.705,7.768,6.910,11.624,all P <0.05).Conclusion The dental restorations with CAD/CAMzirconia all -ceramic crowns and CAD/CAM zirconia all -ceramic onlays show satisfactory clinical performance in short time.

Objective To analyze the diagnostic methods and etiological factors in patients with fever of unknown origin (FUO).Methods The clinical data of 358 patients with FUO,Who were treated in hospital since February 2001 to April 2005,were retrospectively analyzed.Results Among the 358 patients,312 patients were definitely agnosed(87.2%),A- mong the 312 definitely diagnosis patients,172 cases were infectious disease(132 cases were bacterial infection,31 cases were virus infection,6 eases were fungus infection and 3 cases belonged to other disese),143 cases were bacterial were non-infections disease(66 cases were collagen vascular diseases,63 cases were malignant tumor and 14 cases belonged to other disese).46 cases remained origin-unknown until they were discharged from hospital.Conclusion In the diag- nosis of FUO,We should manage to collect oathogenic,immunologic and pathologic evidences.Infectious diseases,collagen vascular diseases and malignant tumors are the main causes of FUO.

Blood Volume ; Child ; Edema ; etiology ; therapy ; Evidence-Based Medicine ; Hemofiltration ; methods ; Humans ; Nephrotic Syndrome ; complications ; therapy ; Renal Dialysis ; methods ; Severity of Illness Index

Coronary Stenosis ; diagnostic imaging ; Humans ; Ultrasonography, Interventional ; methods

Child ; Evidence-Based Medicine ; Humans ; Kidney Diseases ; therapy

Child ; Humans ; Urolithiasis ; diagnosis ; therapy

Child ; Chronic Disease ; Guidelines as Topic ; Humans ; Kidney Diseases ; therapy ; Kidney Failure, Chronic ; Nutritional Support ; Renal Insufficiency, Chronic

Despite a combination of all available treatment, the mortality of liver failure is very high,especially in children patients. Artificial liver support methods have been tested for over 50 years. Standard techniques of blood purification like hemodialysis, adsorption, hemo or plasma filtration as well as bioreactorbased approaches using liver cells or tissues have been used. It' s believed that the damaged liver has the ability to return to normal. Artificial liver support systems are expected to be useful for temporary support of liver function. If the liver does not regenerate to normal functions, an artificial liver support system may be useful as a bridge to liver transplantation. In conclusion, artificial liver support method appears to be a reliable therapy for advanced liver diseases and has significantly decreased the mortality of liver failure. Artificial liver support system has been used in children patients as well, but it still needs more researches.

Objective The aim of this study was to understand the role of specific markers of stem cells Oct-4 expression in the development of human epidermal non-melanoma cutaneous tumors.Methods The paraffin-embedded samples were retrieved from files of pathology department at our hospital,including 20 cases of skin squamous cell carcinomas (SCC),20 cases of basal cell carcinomas (BCC),20 cases of seborrhoeic keratosis (SK) and 20 cases of normal skin (from head,face,trunk,extremities).The expression of Oct-4 and PCNA were observed by immunohistochemical staining technique.Results Oct-4 protein was abnormally increased in SCC and BCC comparel to normal skin and SK ( P ＜0.05 ).However there were no significant difference of Oct-4 protein expression between SCC and BCC ( P ＞0.05).There were also no significantly different Oct-4 protein expression between Sk and the normal skin ( P ＞ 0.05 ),and no significantly different Oct-4 protein expression between SK and BCC( P ＞0.05 ).PCNA protein was abnormally increased in SCC and BCC compared to normal skin and SK ( P ＜0.01 ).There were significantly different PCNA protein expression between SCC and BCC( P ＜0.05).There were also significantly different PCNA protein expression between SK and the normal skin ( P ＜ 0.05 ).However there were no significant difference of PCNA protein expression between SK and BCC ( P ＞ 0.05 ).There were positive correlation between the expression intensity of Oct-4 and PCNA in SCC and BCC.Conclusions The abnormal expression of Oct-4 may have an important role in the development of BCC and SCC.Positive Oct-4 expression cells may be the tumor stem cell in SCC and BCC.There were positive correlation between the expression intensity of Oct-4 and PCNA in SCC and BCC.The over expression Oct-4 in BCC and SCC may play an important role in proliferation of tumor.