Fifteen cases of chronic pelvic inflammation were treated by needling Guanyuan (CV 4), Qihai (CV 6), Sanyinjiao (SP 6), Zhongji (CV 3), Shidao (ST 28), Diji (SP 8), Zusanli (ST 36), Shenshu (BL 23), Dachangshu (BL 25) and Ciliao(BL 32) in combination with herbal enema effective to clear heat and relieve toxin, activate blood and resolve stagnant blood.After 2-course treatment, 13 cases were cured and 2 cases were improved.

OBJECTIVE:To discuss the working pattern and importance of providing pharmaceutical care for medical staff and patients. METHODS:The practical experiences of providing integrated pharmaceutical care for medical staff and patients in our hospital were summarized. RESULTS&CONCLUSION:Only new working pattern of human- oriented hospital pharmacy is established and pharmaceutical care for medical staff and patients is provided,does the combination of pharmacists,doctors and nurses in the medical practice realize.

OBJECTIVE Through detecting hepatitis B virus markers and hepatitis B virus DNA,to probe into the significance of HBV-DNA detection in HBsAg negative blood donors for blood transfusion safety.METHODS ELISA was used for detecting hepatitis B virus markers,and real-time fluorescent quantitative PCR assay was introduced for measuring HBV-DNA.RESULTS Totally 1 698 samples from HBsAg negative blood donors were examined,the positive rate of HBV-DNA was 2.71%.The rate of the HBsAb positive and HBcAb positive group,the HBsAb positive,HBeAb positive and HBcAb positive group,the HBcAb positive group,the HBeAb positive and HBcAb positive group,the HBsAb positive group and the all hepatitis B virus markers negative group were 5.71%,3.60%,6.60%,2.77%,38.48% and 46.94%,respectively.The positive rate of HBV-DNA in these groups were 7.22%,8.20%,4.46%,8.51%,1.21% and 2.26%,respectively.CONCLUSIONS It′s very important for blood transfusion safety to detect HBV-DNA in HBsAg negative blood donors.The more economic,reasonable and effective detecting method should be developed for blood transfusion safety.

Next generation sequencing (NGS) based test provided us an unprecedented power for the molecular diagnosis of rare diseases with genetic etiology, thus enabling the practice of precision medicine.In order to maximize the clinical utilities of NGS-based test, attention should be paid to the improvement of the sequencing technology, data quality and the accuracy of data interpretation, as well as the clinical correlations and pre-and post-test genetic counseling services.In doing so, it is believed practice of NGS-based test can bring expected benefit to many patients and families.

This paper reports on the effect of the culture supernatant of NPC cell line (CNE-2S) (400?l/ml) on cAMP、IL-2、and IL-2 receptor in normal lymphocyts. The cAMP levels of lymphocytes from 11 cases was 13.77?4.92pm/1?10~6. With lymphocytes suspensives added to the CNE-2S, the cAMP levels was increased to 26.1? 15.14Pm/1?10~6(P0.05)These results show that the immune function abnormality of the patients with NPC relates to the fact of that the NPC immunologic inhibitory factor declines the ability of lymphocytes to produce IL-2.

Hepatocellular carcinoma (HCC)is a common malignant tumor in the world,and surgical resection and liver transplantation are two radical treatment modalities,but only 10%-20%of all patients can receive such treatments.In recent years,local therapies including radiofrequency ablation,microwave ablation,cryoablation,and the irreversible electroporation ablation which appeared recently have gradu-ally become the alternative therapies for the patients who are unable to undergo surgery.In addition to local tumor growth control and im-provement in survival outcomes,the ablation technology also helps to downgrade tumor for secondary resection.This article focuses on the re-search progress in radiofrequency ablation alone and in combination with other therapies in the treatment of HCC,compares radiofrequency ablation with other local ablative therapies,and briefly introduces the application of intelligent navigation technology in adjuvant ablation. With the development of medical imaging and progress in related fields,the ablation technology will be widely applied in clinical practice in the future.

OBJECTIVE:To probe into the economic-effectiveness of different therapeutic schemes in the treatment of lower respiratory tract infections(LRTI).METHODS:86cases of LRTI were randomly divided into 2 groups:Group A received intravenous cefuroxime sodium while Group B received intravenous cefuroxime sodium and oral cefuroxime axetil sequential therapy.Cost-effectiveness of the 2 schemes was analyzed.RESULTS:The costs of the 2 therapeutic schemes were 677.60 yuan and 439.58 yuan(P0.05)respectively;the cost-effectiveness ratio of the 2 were 7.67 and 5.11 respectively.CONCLUSION:Scheme B was better than Scheme A in the treatment of lower respiratory tract infection.

OBJECTIVE: To evaluate the utilization and its trend of narcotic analgetics in this hospital.METHODS: The use of narcotic analgetics during the period 2005-2007 in our hospital was analyzed retrospectively.RESULTS: The consumption quantity of narcotic analgetics in our hospital increased year-on-year,much as in the consumption of morphine preparations,with oral morphine preparations dominating the 3 first places over the 3 years,however,the increase of pethidine was slowed down in consumption quantity.CONCLUSION: The use of narcotic analgetics in our hospital is rational on the whole,but measures should be taken to tighten the control on the use of narcotic analgetics.

The medication record of Chinese medicine is not only a complete record of the clinical practice of clinical pharma-cists, but also the essential data for clinical pharmacists to carry out pharmaceutical care. However, at present, there is no unified standard for the medication record of Chinese medicine. Based on the purpose, significance, content and focus, the paper made pre-liminary discussion on the writing of medication record of Chinese medicine, which bulit a preliminary framework for the writing of med-ication record of Chinese medicine.

Objective To investigate the effects of Benazepril on inflammatory cytokines in patients with primary hypertension and its efficacy analysis.Methods 72 patients with mild to moderate primary hypertension were randomly divided into benazepril group(37 cases)and control group(35 cases).The control group patients were given felodipine sustained release tablets Stag,1 times daily.Benazepril group were given benazepril tablets 10mg,1 times daily.Both groups were treated for 8 weeks.Changes in blood pressure and heart rate,plasma inflammatory cytokine levels and the adverse reactions were observed.Results After 8 weeks of treatment,the patients' blood pressures were significantly decreased (t =2.87,2.43,2.31,2.23,P ＜ 0.05 or P ＜ 0.01) than before in both groups.And the decrease in the benazepril group was more obvious than that in the control group (t =2.21,2.13,all P ＜ 0.05),while the patients' heart rates in the two groups showed no significant change (P ＞ 0.05) ; Patients' plasma IL-4 and IL-8 levels decreased significantly,plasma IL-10 levels increased significantly (t =2.99,2.87,3.21,2.13,2.19,2.23,all P＜0.05 or P＜0.01),and the magnitude of decrease or increase in the benazepril group were more obvious compared with the control group (t =2.21,2.13,2.34,all P ＜ 0.05).Conclusion Benazepril in the treatment of primary hypertension has good antihypertensive effect and security which can significantly reduce the plasma levels of proinflammatory cytokines IL-4 and IL-8 levels,improve the anti-inflammatory cytokine IL-10 levels,and has the role of suppressing the inflammatory response of the vessel wall.