1.CHANGE OF FOREARM MUSCLE OXYGEN CONSUMPTION IN PEDIATRIE KIDNEY TRANSPLANT PATIENTS
SANPEI MIYAKAWA ; NAOKO MATSUMOTO ; HIROKO CHIKAMOTO ; MOTOSHI HATORI ; KATSUMI ITO ; TAKU ADACHI ; SHIGERU KITAME ; SHIRO ICHIMURA ; TAKUYA OSADA ; TOSHIHITO KATSUMURA ; TAKAFUMI HAMAOKA
Japanese Journal of Physical Fitness and Sports Medicine 2006;55(Supplement):S25-S28
The aim of the present study is to clarify the improvement of peripheral muscle oxygen consumption after successful renal transplantation. We investigated change of forearm (brachioradial muscle) muscular oxygen consumption in chronic renal failure children before and after renal transplantation. by using near-infrared spectroscopy.Oxygen consumption of brachioradial muscle was increased significantly after succesful renal transplantation. And half recovery time of brachioradial muscle oxygenation in arterial occlusion and exercise were decreased after renal transplantation.These results suggest that increased muscular blood flow and increased oxidative generation of ATP might contribute to the increased oxygen turn over after renal transplantation.
2.Long-term study of urinary bisphenol A in elementary school children.
Yuko YAMANO ; Sanpei MIYAKAWA ; Kyoichi IIZUMI ; Hiroaki ITOH ; Motoki IWASAKI ; Shoichiro TSUGANE ; Jun KAGAWA ; Toshio NAKADATE
Environmental Health and Preventive Medicine 2008;13(6):332-337
OBJECTIVESDue to its industrial application and frequent use as a coating material for food containers, bisphenol A (4,4'-isopropylidenediphenol, BPA) is present in abundance in our environment. Data on intake levels of BPA are limited in preadolescent children in Japan. This study was designed to help us better understand the current state of BPA exposure in children in Japan.
METHODSWe followed first graders (n = 104) attending school in a Tokyo suburb from 1998 until the sixth grade (2003), during which time we collected a total of three morning urine samples. Urinary BPA was analyzed using high-performance liquid chromatography isotope-dilution tandem mass spectrometry.
RESULTSNinety-four children were followed for 5 years. Median urinary BPA level was 2.66 ng/mg creatinine (CRE) (range 0.9-38.9) at first grade (1998), 1.52 ng/mg CRE (0.4-11.8) at third grade (2000), and 0.66 ng/mg CRE (0.2-8.5) at sixth grade (2003), showing a significant decrease in urinary BPA levels over a 5-year follow-up study (p < 0.001). No significant difference was seen between boys and girls at each grade.
CONCLUSIONSUrinary levels of BPA were relatively low throughout the study period; however, as the study progressed, we observed a significant decline in levels, the reason behind which is not yet clear.
Result Analysis
Print
Save
E-mail