1.Early Diagnosis of Intrahepatic Pseudoaneurysm during Radiofrequency Ablation using Contrast-Enhanced Ultrasound
S Krishna Kumar ; Ong Keh Oon ; Paul Horgan ; Edward Leen
Malaysian Journal of Medical Sciences 2015;22(6):58-62
Radiofrequency ablation is one of the more established forms of local treatment in patients with unresectable tumours, including colorectal hepatic metastases. Complications associated with this method of intervention include thermal and mechanical injuries, including vascular insults resulting in haemorrhage or pseudoaneurysm formation. This is the first case demonstrating the detection of post-ablation acute pseudoaneurysm formation identified on the table using contrast-enhanced ultrasound (CEUS) and the subsequent successful management.
2.Positron emission mammography is a useful adjunct in assessment of dense breasts
S Krishna Kumar ; Patricia Bernal Trujillo ; Gonzalo Rodriguez Ucros
The Medical Journal of Malaysia 2017;72(2):138-140
Worldwide breast cancer remains as the most common
malignancy in women and the numbers who form a
subgroup with dense breast parenchyma are substantial. In
addition to mammography, the adjuncts used for further
evaluation of dense breasts have been anatomically based
modalities such as ultrasound and magnetic resonance
imaging. The practice of functionally based imaging of
breasts is relatively new but has undergone rapid progress
over the past few years with promising results. The value of
positron emission mammography is demonstrated in
patients with dense breasts and mammographically occult
disease.
Breast Neoplasms
;
Mammography
3.Tongue-lip adhesion in Pierre Robin sequence.
K. S. KRISHNA KUMAR ; Suresh VYLOPILLI ; Anand SIVADASAN ; Ajit Kumar PATI ; Saju NARAYANAN ; Santhy Mohanachandran NAIR
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2016;42(1):47-50
Patients with Pierre Robin sequence exhibit varying degrees of airway obstruction and feeding difficulty. In some patients, airway obstruction may be profound, warranting surgical intervention to maintain a patent airway. The purpose of this article is to highlight the advantages of the tongue-lip adhesion procedure for the management of airway obstruction in such patients compared to the currently available options.
Airway Obstruction
;
Humans
;
Pierre Robin Syndrome*
4.Opioid use amongst cancer patients at the end of life.
Lalit Kumar Radha KRISHNA ; Jissy Vijo POULOSE ; Benjamin S A TAN ; Cynthia GOH
Annals of the Academy of Medicine, Singapore 2010;39(10):790-797
INTRODUCTIONConcerns about the life shortening effect of opioids is a well known fact in the medical world when considering administration of these drugs for symptom alleviation at end of life. This study described the patterns of opioid use among cancer patients referred to a hospital-based specialist palliative care service for symptom management. This study also examined whether opioid use among terminally ill cancer patients during the last 2 days of life had any influence on survival.
MATERIALS AND METHODSA retrospective review of case notes of patients who were diagnosed with terminal cancer and had passed away in a 95-bedded oncology ward between September 2006 and September 2007 was conducted. Data were collected on patients' characteristics and patterns of opioid use including opioid doses and dose changes at 48 hours and 24 hours before death.
RESULTSThere were 238 patients who received specialist palliative care, of whom 132 (55.5%) were females. At 48 hours and 24 hours before death, 184 (77.3%) patients and 187 (78.6%) patients had received opioids, respectively. The median daily doses at 48 hours and 24 hours were 48 mg and 57 mg oral morphine equivalent doses (OME), respectively. Indications for opioid use were pain (41.1%), dyspnoea, (29.1%) and both dyspnoea and pain (30.8%). In the fi nal 24 hours, 22.3% patients had a reduction in their mean opioid dose while 22.7% required an increase in their mean opioid dose. Increased age was associated with decreasing opioid doses (P = 0.003). Patients with spinal metastases required higher doses of opioids (P = 0.03) while those with lung metastases required lower doses (P = 0.011). Survival analysis using Kaplan-Meier survival curve revealed no significant survival difference between those who were on opioids and those who were not. Log rank test (Mantel-Cox) (P = 0.69).
CONCLUSIONOur results showed that opioids are safe medications for symptom alleviation in terminally ill cancer patients during the last days of life and have no deleterious influence on survival.
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Analgesics, Opioid ; administration & dosage ; therapeutic use ; Female ; Humans ; Male ; Medical Audit ; Middle Aged ; Neoplasms ; physiopathology ; Retrospective Studies ; Survival Analysis ; Terminal Care ; Young Adult
5.Laparoscopic subtotal cholecystectomy in difficult gallbladder: Our experience in a tertiary care center
Kulbhushan HALDENIYA ; Krishna S. R. ; Annagiri RAGHAVENDRA ; Pawan Kumar SINGH
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(2):214-219
Background:
s/Aims: Open cholecystectomy is becoming obsolete and laparoscopic cholecystectomy has become the treatment of choice in gallstone diseases. Difficult gallbladders are encountered whenever there is a frozen calot’s triangle, obliterated cystic plate, or both. Rather than converting to open procedure, there has been a growing preference for laparoscopic subtotal cholecystectomy (LSC) during difficult gallbladders. This study aimed to assess the advantages, indications, and viability of LSC in difficult gallbladders.
Methods:
The study included patients undergoing laparoscopic cholecystectomy in NIMS Hospital, Jaipur, from January 2021 to January 2023. Data of the patients who underwent LSC for difficult gallbladders included demographics, comorbidities, operative time, conversion to open cholecystectomy, length of hospital stay, and complications. LSC was classified into three types depending on the part of the gallbladder remnant.
Results:
A total of 728 patients underwent laparoscopic cholecystectomy. Among them, 41 patients (5.6%) were attempted for LSC.However, one patient was converted to an open procedure and the rest 40 underwent LSC. LSC was divided into 3 types, 4 patients underwent LSC type I, 34 patients underwent type II, and 2 patients type III. The average operating time and postoperative length of hospital stay were 86.2 minutes and 2.1 days, respectively. Two patients had surgical site infection. No patient had a bile leak and none required intensive care unit care.
Conclusions
LSC is a safe and feasible option for use in difficult gallbladders.
6.Laparoscopic subtotal cholecystectomy in difficult gallbladder: Our experience in a tertiary care center
Kulbhushan HALDENIYA ; Krishna S. R. ; Annagiri RAGHAVENDRA ; Pawan Kumar SINGH
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(2):214-219
Background:
s/Aims: Open cholecystectomy is becoming obsolete and laparoscopic cholecystectomy has become the treatment of choice in gallstone diseases. Difficult gallbladders are encountered whenever there is a frozen calot’s triangle, obliterated cystic plate, or both. Rather than converting to open procedure, there has been a growing preference for laparoscopic subtotal cholecystectomy (LSC) during difficult gallbladders. This study aimed to assess the advantages, indications, and viability of LSC in difficult gallbladders.
Methods:
The study included patients undergoing laparoscopic cholecystectomy in NIMS Hospital, Jaipur, from January 2021 to January 2023. Data of the patients who underwent LSC for difficult gallbladders included demographics, comorbidities, operative time, conversion to open cholecystectomy, length of hospital stay, and complications. LSC was classified into three types depending on the part of the gallbladder remnant.
Results:
A total of 728 patients underwent laparoscopic cholecystectomy. Among them, 41 patients (5.6%) were attempted for LSC.However, one patient was converted to an open procedure and the rest 40 underwent LSC. LSC was divided into 3 types, 4 patients underwent LSC type I, 34 patients underwent type II, and 2 patients type III. The average operating time and postoperative length of hospital stay were 86.2 minutes and 2.1 days, respectively. Two patients had surgical site infection. No patient had a bile leak and none required intensive care unit care.
Conclusions
LSC is a safe and feasible option for use in difficult gallbladders.
7.Laparoscopic subtotal cholecystectomy in difficult gallbladder: Our experience in a tertiary care center
Kulbhushan HALDENIYA ; Krishna S. R. ; Annagiri RAGHAVENDRA ; Pawan Kumar SINGH
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(2):214-219
Background:
s/Aims: Open cholecystectomy is becoming obsolete and laparoscopic cholecystectomy has become the treatment of choice in gallstone diseases. Difficult gallbladders are encountered whenever there is a frozen calot’s triangle, obliterated cystic plate, or both. Rather than converting to open procedure, there has been a growing preference for laparoscopic subtotal cholecystectomy (LSC) during difficult gallbladders. This study aimed to assess the advantages, indications, and viability of LSC in difficult gallbladders.
Methods:
The study included patients undergoing laparoscopic cholecystectomy in NIMS Hospital, Jaipur, from January 2021 to January 2023. Data of the patients who underwent LSC for difficult gallbladders included demographics, comorbidities, operative time, conversion to open cholecystectomy, length of hospital stay, and complications. LSC was classified into three types depending on the part of the gallbladder remnant.
Results:
A total of 728 patients underwent laparoscopic cholecystectomy. Among them, 41 patients (5.6%) were attempted for LSC.However, one patient was converted to an open procedure and the rest 40 underwent LSC. LSC was divided into 3 types, 4 patients underwent LSC type I, 34 patients underwent type II, and 2 patients type III. The average operating time and postoperative length of hospital stay were 86.2 minutes and 2.1 days, respectively. Two patients had surgical site infection. No patient had a bile leak and none required intensive care unit care.
Conclusions
LSC is a safe and feasible option for use in difficult gallbladders.
8.Laparoscopic subtotal cholecystectomy in difficult gallbladder: Our experience in a tertiary care center
Kulbhushan HALDENIYA ; Krishna S. R. ; Annagiri RAGHAVENDRA ; Pawan Kumar SINGH
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(2):214-219
Background:
s/Aims: Open cholecystectomy is becoming obsolete and laparoscopic cholecystectomy has become the treatment of choice in gallstone diseases. Difficult gallbladders are encountered whenever there is a frozen calot’s triangle, obliterated cystic plate, or both. Rather than converting to open procedure, there has been a growing preference for laparoscopic subtotal cholecystectomy (LSC) during difficult gallbladders. This study aimed to assess the advantages, indications, and viability of LSC in difficult gallbladders.
Methods:
The study included patients undergoing laparoscopic cholecystectomy in NIMS Hospital, Jaipur, from January 2021 to January 2023. Data of the patients who underwent LSC for difficult gallbladders included demographics, comorbidities, operative time, conversion to open cholecystectomy, length of hospital stay, and complications. LSC was classified into three types depending on the part of the gallbladder remnant.
Results:
A total of 728 patients underwent laparoscopic cholecystectomy. Among them, 41 patients (5.6%) were attempted for LSC.However, one patient was converted to an open procedure and the rest 40 underwent LSC. LSC was divided into 3 types, 4 patients underwent LSC type I, 34 patients underwent type II, and 2 patients type III. The average operating time and postoperative length of hospital stay were 86.2 minutes and 2.1 days, respectively. Two patients had surgical site infection. No patient had a bile leak and none required intensive care unit care.
Conclusions
LSC is a safe and feasible option for use in difficult gallbladders.
9.Percutaneous transluminal angioplasty of transplant renal artery stenosis.
Lee Lian CHEW ; Bien Soo TAN ; Krishna KUMAR ; Maung Myint HTOO ; Kok Seng WONG ; Christopher W S CHENG ; Terence K B TEO ; Farah Gillani IRANI ; Hui Lin CHOONG ; Kiang Hiong TAY
Annals of the Academy of Medicine, Singapore 2014;43(1):39-43
INTRODUCTIONThis study aimed to assess the outcome of percutaneous transluminal angioplasty (PTA) as the primary treatment for transplant renal artery stenosis (TxRAS).
MATERIALS AND METHODSA retrospective review of PTA of TxRAS from April 1999 to December 2008 was performed. Twenty-seven patients (17 males (M):10 females (F)) with the mean age of 49.5 years underwent PTA of TxRAS in the review period. Indications for PTA were suboptimal control of hypertension (n=12), impaired renal function (n=6) and both suboptimal control of hypertension and impaired renal function (n=9). All patients had doppler ultrasound scans prior to their PTA. In addition, 5 of these patients had computed tomography angiography (CTA) and another 7 had magnetic resonance angiography (MRA) evaluation. Mean follow-up period was 57.0 months (range, 7 to 108 months).
RESULTSThe stenotic lesions were located proximal to the anastomosis (n=2), at the anastomosis (n=15), and distal to the anastomosis (n=14). Technical success rate was 96.3%. One case was complicated by extensive dissection during PTA, resulting in subsequent graft failure. The overall clinical success rate was 76.9%. Seven out of 26 patients had restenoses (26.9% of cases). These were detected at a mean of 14.3 months post angioplasty (range, 5 to 38 months). All 7 patients underwent a second PTA successfully. Three of these patients required more than 1 repeat PTA.
CONCLUSIONPTA is safe and effective in the management of symptomatic TxRAS and should be the primary treatment of choice. Close surveillance for restenosis is required and when diagnosed, re-angioplasty can be performed.
Adult ; Angioplasty ; Female ; Humans ; Kidney Transplantation ; Male ; Middle Aged ; Postoperative Complications ; surgery ; Renal Artery Obstruction ; surgery ; Retrospective Studies ; Time Factors
10.Is Quadriceps-Strengthening Exercises (QSE) in MedialCompartment Knee Osteoarthritis with Neutral and Varus Malalignment a Paradox? – A Risk-Appraisal of StrengthTraining on Disease Progression
Garg R ; Krishna A ; Daga R ; Arora S ; Puri S ; Kumar M
Malaysian Orthopaedic Journal 2024;18(No.1):73-83
Introduction: The present inquiry seeks to investigate
whether the current regimens of QSEs (QuadricepsStrengthening Exercises) aggravate the disease while
mitigating symptoms.
Materials and methods: A comparative study was
conducted on 32 patients with medial compartment
osteoarthritis of knees. While the neutral group of 16 patients
was constituted of those with an anatomical-lateral-femorotibial-angle (aFTA) 176-180º, varus group comprised an
equal number of patients with an aFTA >180º. A home-based
12-week strength-training program involving weekly visits
to hospital for supervised sessions was administered. The
outcome measures were visual-analog-scale (VAS), medial
patello-femoral joint tenderness (MPFJT), time-up-and-gotest (TUGT), stair-climb test, step test, WOMAC, IKDC
scores, aFTA, hip-knee-ankle (HKA) angle, lateral-tibiofemoral-joint-separation (LTFJS), and horizontal-distancefrom-centre-of-knee-to-Mikulicz-line.
Results: There was a significant increase in quadriceps
strength (p<0.01) in both groups. Values for neutral group
with VAS score (p=0.01), MPFJT (p=0.01), TUGT (p=0.01),
timing of the stair climb test (p=0.01), WOMAC (p<0.01),
and IKDC (p=0.03) were better compared to varus group
with VAS score (p=0.13), MPFJT (p=0.03), TUGT (p=0.90),
timing of stair climb test (p=0.68), WOMAC (p<0.02), and
IKDC (p=0.05). Varus group also showed an increase in
aFTA and LTFJS in 12 patients, increase in HKA in 11, and
increase in horizontal distance from the centre of knee to the
Mikulicz line in 7 patients.
Conclusion: The present study brings to the fore the
paradoxical role played by QSEs in management of medial
knee OA. While there is a radiological progression of the
disease in both neutral and varus mal-aligned knees more so
in the latter than the former.