1.The Pupillary Dilatation Effect of Phenylephrine 2.5% Versus 10% in Patients with Diabetes.
Yong In LEE ; Joon Soon KIM ; Ki Ryong NAM
Journal of the Korean Ophthalmological Society 1997;38(9):1655-1659
We assessed the degree of mydriasis induced by 1% tropicamide and 2.5% phenylephrine compared with that induced by 1% tropicamide and 10% phenylephrine in 100 patients with diabetes. Additionally we studied the difference of pupillary dilatation according to duration of dibetes, severity of retinopathy, and performance of photocoagulation. Maximum dilated pupillary diameter was 7.25+/-1.27mm in 2.5% phenylephrine group and 7.32+/-1.36mm in 10% phenylephrine group, respectively the difference in pupillary dilatation between two groups was not statistically significant. We advise the use of the 2.5% phenylephrine in patients with diabetes, who already exhibit a higher prevalence of vascular disease and autonomic nerve system dysfunction because 2.5% phenylephrine may produce a lower incidence of side effects than 10% concentration and have the same effect of pupil dilatation as 10% phenylephrine.
Autonomic Pathways
;
Dilatation*
;
Humans
;
Incidence
;
Light Coagulation
;
Mydriasis
;
Phenylephrine*
;
Prevalence
;
Pupil
;
Tropicamide
;
Vascular Diseases
2.A case of malignant lymphoma presenting as acute renal failure.
Hyun Jae SHIN ; Dae Ryong CHA ; Won Yong CHO ; Hyoung Kyu KIM ; Nam Hee WON
Korean Journal of Nephrology 1993;12(3):470-475
No abstract available.
Acute Kidney Injury*
;
Lymphoma*
3.Photodisruption of Premacular Hemorrhage with Nd: YAG Laser.
Woojin LEE ; Joon Soon KIM ; Ki Ryong NAM
Journal of the Korean Ophthalmological Society 1999;40(7):2020-2026
Premacular hemorrhage (preretinal,subhyaloid, or sub-internal limiting membrane hemorrhage)impairs central vision abruptly and occurs in various underlying diseases. In cases of persistent hemorrhage, permanent impairment of vision may occur. Proposed therapeutic options for premacular hemorrhage consist of conservative treatment, laser photodisruption and early vitrectomy. Laser photodisruption may be performed in cases of persistent or slow-clearing hemorrhage, in patients with occupational need for prompt restoration of binocular vision or in patients with poor vision in their fellow eyes. The authors report 4 patients with premacular hemorrhage who were treated with Nd: YAG laser photodisruption with the review of the literatures.
Hemorrhage*
;
Humans
;
Lasers, Solid-State*
;
Membranes
;
Vision, Binocular
;
Vitrectomy
4.Effect of diazepam on haloperidol-induced DOPAC increase in the rat brain.
Young Nam PARK ; Soo Kyung KIM ; Sugn Ryong LEE ; Sung Won CHO
Journal of Korean Neuropsychiatric Association 1993;32(2):178-187
No abstract available.
3,4-Dihydroxyphenylacetic Acid*
;
Animals
;
Brain*
;
Diazepam*
;
Rats*
5.Clinical Study of Breast Cancer Patients Who Had More Than 10 Positive Axillary Lymph Nodes.
Journal of Breast Cancer 2005;8(1):76-82
PURPOSE: Nodal involvement has long been known to represent the single most reliable indicator of the prognosis for early-stage breast cancer. In common parlance, high-risk node-positive breast cancer has generally been used to describe patients who have involvement of ten or more axillary lymph nodes (10+LN). Breast cancer patients who had 10+LN clearly have a strikingly high risk of tumor recurrence and death. Thus we tried to evaluate the clinical courses of breast cancer patients who had more than 10 positive axillary lymph nodes. METHODS: Of the 587 breast cancer patients who were operated on at Chungnam National University Hospital from February 1992 to November 1999, 31 cases (5.3%) showed involvement of more than 10 axillary lymph nodes. We evaluated the clinical courses of these patients and the differences in survival according to the clinical and pathologic vaiables. Survival was calculated using the Kaplan-Meier method. RESULTS: The mean age of the patients was 50+/-4 years. A mastectomy was done in 28 cases (90.3%), and a breast conserving operation was done in 3 cases (9.7%). The mean tumor size was 4.8+/-.5 cm. The mean number of removed axillary Lymph Nodes was 23.5+/-0.2 (range:10-52), and the mean number of positive axillary LNs was 20.0+/-10.1 (10-51). At a median follow-up of 30.5 months, 23 cases (74.2%) of recurrence were noted. Among these 23 cases (69.6%) showed distant metastases as the first recurrence. The 3-year and 5-year disease-free survivals were 28.6% and 22.9%, respectively. The 3-year and 5-year expected overall survivals were 53.7% and 41.8%, respectively. There were significantly more recurrences in patients who had given up taking their adjuvant chemotherapy than for those patients who had completed 6 cycles of FEC or MMM. Also, significant survival benefits were noted in those patients who were treated using a combination chemotherapy with taxane plus cisplatin after their tumor recurrence. CONCLUSION: Breast cancer patients with 10+LNs have a strikingly high risk of tumor recurrence. Six cycles of adjuvant chemotherapy with FEC or MMM was a controllable variable for lowering the risk of tumor recurrence. A combination chemotherapy with taxane and cisplatin was also a controllable variable for increasing survival after tumor recurrence.
Breast Neoplasms*
;
Breast*
;
Chemotherapy, Adjuvant
;
Chungcheongnam-do
;
Cisplatin
;
Disease-Free Survival
;
Drug Therapy, Combination
;
Follow-Up Studies
;
Humans
;
Lymph Nodes*
;
Mastectomy
;
Neoplasm Metastasis
;
Prognosis
;
Recurrence
6.Clinical observations on human rotavirus gastroenteritis.
Seung Ryong HAN ; Seung Hyun SEO ; Ki Sik MIN ; Jong Wan KIM ; Kwang Nam KIM ; Ki Yang RYOO
Journal of the Korean Pediatric Society 1992;35(2):226-233
No abstract available.
Gastroenteritis*
;
Humans*
;
Rotavirus*
7.Two Operated cases in Juvenile Diabetic Cataract.
Kie Ryong KIM ; Young Ja HWANG ; Wan Seop SHIM
Journal of the Korean Ophthalmological Society 1979;20(3):421-424
Of the complictions of cataract extraction, it is well known that hemorrhage, infection and delayed wound healing are more frequent in diabetics than in nondiabetics. But if the extraction was performed after diabetes has adequately controlled for several weeks prior to operation, the visual results are almost as good in diabetics as in non-diabetics. However, with precautions for these complications, the aut hers carefully performed cataract extraction in two juvenile diabetics, whose blood sugar level had been poorly controlled in spited of diabetic diet and subcutaneous injection of the insulin before and after operation. The visual results were very good in spite of high blood sugar level before operation.
Blood Glucose
;
Cataract Extraction
;
Cataract*
;
Diet, Diabetic
;
Hemorrhage
;
Injections, Subcutaneous
;
Insulin
;
Wound Healing
8.A Case of Sympathetic Ophthalmia.
Gi Ryong NAM ; Yoon Bo SHIM ; Bong Cheol KIM
Journal of the Korean Ophthalmological Society 1987;28(6):1391-1394
Sympathetic ophthalmia is a rare, diffuse, granulomatous inflammation of the entire uvea, usually bilateral, which occurs days, months, or years after penetrating ocular injury or intraocular surgery. This presented case was a 34 years old male patient injured his left eye suspecting a scleral laceration. The exciting eye(left) was eviscerated 8 days after injury and sympathetic eye(right) was developed sympathetic ophthalmia 8 weeks after injury. A brief review of the related literatures is presented.
Adult
;
Humans
;
Inflammation
;
Lacerations
;
Male
;
Ophthalmia, Sympathetic*
;
Uvea
9.Wegener's granulomatosis with ANCA.
Do Sun LIM ; Dae Ryong CHA ; Young Ju KWON ; Won Yong CHO ; Hyung Kyu KIM ; Nam Hee WON
Korean Journal of Nephrology 1992;11(4):462-467
No abstract available.
Antibodies, Antineutrophil Cytoplasmic*
;
Wegener Granulomatosis*
10.Cortical Blindness After Cerebral Angiography.
II Taek KWON ; Ki Ryong NAM ; Bong Cheol KIM
Journal of the Korean Ophthalmological Society 1992;33(12):1238-1242
Cortical blindness means visual loss caused by bilateral destruction of visual cortex. Cortical blindness can develop after cerebral angiography due to hypertonic contrast medium which open the blood-brain barrier and then alternate the function of visual cortex transiently. About 30 minutes after injection of contrast medium (Ultravist 370(R)) during cerebral angiography, the patient complained of decrease of visual acuity. And 3 hours later, evaluation revealed that she could not see even the light. But her vision began to improve after 19 hours and recovered completely after 7 days. MRI taken at 12 hours after cerebral angiography showed high signal intensities in the both occipital lobes. But in repeated MRI study, which was taken after 3 days, previously noted high densities were completely disappeared. So we diagnosed this case as cortical blindness caused by hypertonic contrast medium.
Blindness, Cortical*
;
Blood-Brain Barrier
;
Cerebral Angiography*
;
Humans
;
Magnetic Resonance Imaging
;
Occipital Lobe
;
Visual Acuity
;
Visual Cortex