Objective: To examine the association between the mobilization level during intensive care unit (ICU) admission and independence in activity of daily living (ADL), defined as Barthel Index (BI)≥70. Methods: This was a post-hoc analysis of the EMPICS study involving nine hospitals. Consecutive patients who spend >48 hours in the ICU were eligible for inclusion. Mobilization was performed at each hospital according to the shared protocol and the highest ICU mobility score (IMS) during the ICU stay, baseline characteristics, and BI at hospital discharge. Multiple logistic regression analysis, adjusted for baseline characteristics, was used to deter-mine the association between the highest IMS (using the receiver operating characteristic [ROC]) and ADL. Results: Of the 203 patients, 143 were assigned to the ADL independence group and 60 to the ADL dependence group. The highest IMS score was significantly higher in the ADL independence group than in the dependence group and was a predictor of ADL independence at hospital discharge (odds ratio, 1.22; 95% confidence interval, 1.07–1.38; adjusted p=0.002). The ROC cutoff value for the highest IMS was 6 (specificity, 0.67; sensitivity, 0.70; area under the curve, 0.69). Conclusion These results indicate that, in patients who were in the ICU for more than 48 hours, that patients with good function in the ICU also exhibit good function upon discharge. However, prospective, multicenter trials are needed to confirm this conclusion.

Objective: This study aimed to investigate the effectiveness of an intervention that applied a behavioral change approach to the usual rehabilitation for patients with hematological malignancies undergoing chemotherapy. Methods: Patients with hematological malignancies undergoing chemotherapy were divided into two groups: patients who underwent conventional rehabilitation (control group, n=12) and a counterpart who received a behavioral change intervention with feedback on motor function and physical activity (feedback group, n=13). We analyzed the changes in motor function and physical activity between the two groups from the start of rehabilitation to discharge. Results: There were a significant difference in walking speed between baseline and discharge. Changes in weekly steps were significantly higher in the feedback group than those in the control group. Conclusion: A behavioral change intervention with feedback on motor function and physical activity may improve voluntary exercise in patients with hematological malignancies undergoing chemotherapy.

Objective: This study aimed to identify factors associated with fatigue in patients with hematological malignancies undergoing chemotherapy. Method: A total of 90 patients with hematological malignancies undergoing chemotherapy were enrolled in this study. Simple regression analysis was performed using total, physical, emotional, and cognitive fatigue as dependent variables. On the other hand, the patient’s sex, age, blood test findings, physical function, activities of daily living (ADL), performance status, presence or absence of anxiety or depression, physical symptoms, and nutritional status were used as independent variables. Multiple regression analysis was conducted with the items that showed significant differences in the simple regression analysis as independent variables. Results: Multiple regression analysis with total fatigue as the dependent variable identified depression as an associated factor. Additionally, physical fatigue was noted to be associated with pain and depression, while emotional fatigue was reported to be associated with ADL and depression. Conclusion: Our results suggest that patients with hematological malignancies who have symptoms of fatigue should be managed taking in consideration possible causes of their fatigue, such as depression, pain, and ADL.

Purpose: This study aimed to understand the details of osteoporosis treatment for cancer patients provided by designated cancer hospitals. Methods: This web-based survey included questions on the evaluation and treatment of osteoporosis in cancer patients provided by physicians in the departments of urology, gynecology, hematology, respiratory medicine, respiratory surgery, gastroenterology medicine and gastroenterology surfery. Results: The gynecology, hematology, breast surgery, and urology departments had high rates of bone densitometry and prescriptions of osteoporosis treatment for cancer patients. The most frequently used selection criteria were age, hormone therapy, and steroid use. Conclusion: Osteoporosis treatment and associated selection criteria for cancer patients is different in each department, so we need to educate the evaluation and treatment of cancer treatment-induced bone loss.