Objective To investigate the effect of right stellate ganglion block(SGB)on postoper-ative shoulder pain in patients receiving laparoscopic cholecystectomy(LC).Methods A total of 104 pa-tients scheduled for LC from April to August 2022,32 males and 72 females,aged 18-64 years,ASA phys-ical status Ⅰ orⅡ,were selected and randomized into two groups:the stellate ganglion block group(group S,n = 51)and the control group(group C,n = 53).Immediately after intubation,0.2%ropivacaine 4 ml was used for ultrasound-guided right SGB in group S,and saline 4 ml was injected at the same site in group C.The number of cases of post-laparoscopic shoulder pain(PLSP)and the duration of PLSP were re-corded within 48 hours after operation.The VAS pain scores of PLSP were recorded to assess the level of PLSP immediately after operation(T1),2 hours after operation(T2),6 hours after operation(T3),12 hours after operation(T4),24 hours after operation(T5),and 48 hours after operation(T6).The number of effective compressions of the PCIA pump and the salvage analgesia were recorded.The adverse reactions such as nausea,vomiting,and abdominal distension were recorded.Results The incidence of PLSP and the rate of patients with PLSP lasting more than 10 hours in group S was significantly lower than those in group C(P＜0.05),and the degree of PLSP in group S was significantly lower than that in group C at T3-T5(P＜0.05).The number of effective compressions of the PCIA pump and the salvage analgesia rate in group S was significantly lower than those in group C(P＜0.05).The incidence of nausea in group S was significantly lower than that in group C(P＜0.05).Conclusion Right stellate ganglion block can reduce the incidence of PLSP in patients receiving LC,relieve the pain degree of PLSP,and reduce the incidence of adverse reactions.

Objective:To develop a Beijing norm of Memory and Executive Screening (MES) scale to facilitate its further promotion and application in the future.Methods:Study subjects were selected based on the inclusion and exclusion criteria, including patients who visited the memory clinic of Xuanwu Hospital of Capital Medical University from March 20, 2017 to January 6, 2021, and normal people recruited simultaneously from community, and trained and qualified investigators conducted questionnaire surveys through face-to-face interviews. Then strict quality control, data collection and statistical analysis were performed.Results:A total of 607 participants were included, including 239 normal people, 293 individuals with subjective cognitive decline (SCD), and 75 individuals with mild cognitive impairment (MCI). There was a negative correlation between the scores of MES and age ( r=-0.19, P<0.001), but a positive correlation between scores of MES and education level ( r=0.29, P<0.001). The optimal cut-off value of this scale in Beijing was 86 points, the area under curve (AUC) of the cut-off value to distinguish MCI was 0.847 (normal people vs MCI) and 0.826 (SCD vs MCI), and after adding demographic variables, AUC showed slight increase (0.847 to 0.850 and 0.826 to 0.847), whereas the differences were not statistically significant ( Znormal peoplevsMCI=0.49, ZSCDvsMCI=1.21, P>0.05). And there was no statistically significant difference between MES and Montreal Cognitive Assessment scales in diagnostic power for normal people and people with MCI ( Zscale alone=1.03, Zafter adding demographic variables=1.13, P>0.05). Conclusions:The MES scale has a better distinguishing power for MCI, and its optimal cut-off value in Beijing is 86 points, which is different from previous studies. In the future, the sample size needs to be further expanded to verify this norm.

BACKGROUND:In recent years,additive manufacturing(also known as 3D printing)has gradually become the mainstream method for producing titanium alloy brackets for removable partial dentures.Heat treatment,as an important method to improve the mechanical properties of 3D printed titanium alloys,has become a current hot topic of attention.OBJECTIVE:To summarize the main heat treatment technologies currently applied to 3D printed titanium alloy specimens(including annealing,solution aging,hot isostatic pressing,and other heat treatments)and their effects on the mechanical properties and microstructure of 3D printed titanium alloy specimens,providing a theoretical basis for improving the heat treatment technology of removable partial denture titanium alloy supports.METHODS:A computer search was conducted on research materials related to 3D printed titanium alloy heat treatment in databases such as CNKI,PubMed,and ScienceDirect.The search period was from 2012 to 2023.A total of 61 articles were selected based on inclusion and exclusion criteria.RESULTS AND CONCLUSION:(1)Using conventional annealing techniques to treat 3D printed titanium alloy specimens,keeping them at 500-900 ℃ for 2-4 hours,can effectively increase the elongation of 3D printed titanium alloy specimens.(2)Compared to conventional annealing techniques,solid solution aging treatment is more complex,and the titanium alloy specimens after solid solution aging treatment exhibit outstanding yield strength and better corrosion resistance.However,the 3D printed titanium alloy specimens after solid solution aging treatment have no advantage in terms of ductility.(3)Hot isostatic pressing treatment can reduce the internal defects of 3D printed titanium alloy specimens,significantly increase the elongation of 3D printed titanium alloy specimens,and increase their fatigue life.(4)Rapid heat treatment can significantly improve the elongation of 3D printed titanium alloy specimens,and the speed is faster.In terms of elongation improvement and heat treatment efficiency,it has more advantages than conventional annealing in the past.(5)The improvement of elongation of 3D printed titanium alloy specimens by cyclic heat treatment exceeds that of conventional annealing.Cyclic heat treatment can significantly improve the grain structure of 3D printed titanium alloy specimens,but the heat treatment time is too long and the efficiency is low.