1.New Development of Effect of Pregnancy Stress of Mother and Fetal
Luying WANG ; Xin WANG ; Ruoguang WANG
Chinese Journal of Clinical Psychology 2006;0(05):-
Pregnancy stress may significantly elevate the level of CRH and cortisol, which contributes to the bad pregnancy outcomes like premature delivery, low birth weight infant even hypertensive disorders complicating pregnancy. It also has close relationship with postpartum depression. In addition, it has a bad influence on offsprings’ mental growth, behavior development and the development of central nervous system.
2.The Key and Analyzing of DUB by Traditional and Western Medicine
Ruoguang WANG ; Zhaoling YOU ; Chunmei LI
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(01):-
Objective To explore the key way of DUB (dysfunctional uterine bleeding) by traditional and western medicine. Method Analyse the traditional medicine's unique understanding of DUB, the symptoms of DUB and the function of Chinese traditional medicine on DUB. And sum up the modern molecular pathology of DUB. Result Chinese traditional medicine has some regulations in curing DUB. And given the modern molecular biology technique, it maybe play an important part in researching the essential of the syndrome of DUB and the function regulation of Chinese traditional medicine. Conclusion DUB, which is an important disease that is in the person of “menstruation adjustment”, “blooding disease”in traditional Chinese gynecology, must be studied systematically first, so as to improve the combination of traditional medicine and western medicine in gynecology.
3.The Study on the Effects of the Components of Mongolian Milkvetch Root and Red Sage Root Compound on the Expression of Matricial Metal Protease-9 (MMP-9) mRNA on Placental Nourish Cells and the Blood Plasma Level of IL-10 in Model Pregnant Rats
Ruoguang WANG ; Zhaoling YOU ; Chunmei LI
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(03):-
Objective To explore the molecular mechanism of elevating placental blood supply by the component from Mongolian Milkurtch and red sage Root. Method Abstract the effective components from Mongolian Milkurtch and red sage Root, apply L-Arginine methy1 ester (L-NAME) to make NO production blocking model, use ELISA to check IL-10 in plasma of 18 d pragant rats, and FISH to check the expression of matricial metal protease-9 (MMP-9) mRNA. Results The plasma level of IL-10 of model group was lower than that of blank group (P 0.05). Conclusion By interving the relationship between IL-10 and MMP-9, the components of Mongolian milkvetch root and red sage root compound may affect the shift and invadation of deciduas, so as to prevent fleet embedding, help building the circulation between mother and embryo, and keep the placental blood supply.