1.A study on risk factors for falling down in elderly people of rural areas in Laizhou City
Lintao LI ; Shengyong WANG ; Zhong YANG ; Chunxia JING ; Xiaomei DONG ; Runsen ZHUANG ; Junxiang DU
Chinese Journal of Geriatrics 2001;0(05):-
Objective To study the status and risk factors for falling down in elderly people in rural areas, and to provide evidences for preventions. Methods A total of 1 003 farmers aged 60 years old and over were surveyed to study the falls occurred during the previous 12 months before March 2001 in the elderly in a town of Laizhou City by cluster sampling method. Results The average incidence of falling down was 22.6%, 15.9% for men and 28.4% for women, respectively. The risk factors of falls included gender, age, single-living, falling history in the previous year, at least combined two kinds of chronic diseases, manifesting at least two symptoms, gait abnormalities, as well as complaining poor physical status and poorer general conditions than the previous year. Less social actions was negatively associated with the falls. Conclusions The falling in the elderly walkers results from an outcome of combination of multifactors. Since the complex pathogenesis, it should be prevented by a combination of several methods.
2.Research progress on the regulatory effect of macrophage extracellular traps on cardiovascular diseases
Xingchen LI ; Qianqian WU ; Kexin ZHAO ; Runsen WANG ; Xiaoping WANG
Journal of Xinxiang Medical College 2024;41(7):614-618
Macrophage extracellular traps(METs)are extracellular fibrous web-like structures produced by macrophages.METs play a crucial role in the development and progression of various cardiovascular diseases(CVDs),including atherosclerosis and myocardial infarction.This article summarizes the mechanism of METs in CVDs,future research directions and the possibility of using METs as potential therapeutic targets for clinical diseases.
3.Pyramiding of 3-resistant-gene to improve rice blast resistance of a restorer line, Fuhui 673.
Zhiwei CHEN ; Huazhong GUAN ; Xiaofang WANG ; Ruixia DONG ; Chenghai ZHUO ; Damei MAO ; Runsen PAN ; Yuanchang ZHOU ; Weiren WU
Chinese Journal of Biotechnology 2019;35(5):837-846
To improve the blast resistance of elite rice restorer line Fuhui 673, 3 blast resistance genes Pi-1, Pi-9 and Pi-kh were introduced into Fuhui 673 from a good-quality restorer line Jinhui 1059 through 3 successive backcrosses followed by one selfing using the technique of marker-assisted selection. Ten near-isogenic lines (NILs) of Fuhui 673 carrying the 3 introduced resistance genes were created. Genotype analysis using 68 SSR markers evenly distributed in the genome indicated that 92.96%-98.59% of the NILs' genetic background had been recovered to Fuhui 673. Both indoor and field resistance tests indicated that the NILs and their hybrids with sterile line Yixiang A were all resistant to rice blast, with resistance levels significantly higher than those of controls Fuhui 673 and hybrid Yiyou 673 (Yixiang A Fuhui 673). In addition, among the 10 hybrids between the NILs and Yixiang A, 2 showed significantly higher yield than and 4 displayed similar yield to that of control Yiyou 673, suggesting that most of the NILs retained the elite characteristics of Fuhui 673. Two new hybrid rice cultivars Liangyou 7283 and Jintaiyou 683 from NIL Line 9 showed high yield, good resistance to blast and moderate growth period in regional trial, suggesting that the NIL Line 9 has a good prospect for application.
Breeding
;
Disease Resistance
;
genetics
;
Genes, Plant
;
genetics
;
Oryza
;
genetics