Objective To analyse the pathological features in 12 patients demonstrated with demyelination lesions of peripheral nerves Methods Twelve abnormaly cases were screened with EMG from 60 cases of multiple sclerosis (MS) Sural nerve biopsy was done in 12 patients and specimens were analyzed by HE and Loyez,and by electronic microscopy Results Myelinated fibers was reduced in sural nerve biopsy in 8 cases and most striking demyelination seen in 11 cases In electronic microscopy,11 cases specimens were shown myelinated losses,regeneration of myelinated fibers,vacuoate,hyperplasia of Schwann cell and typical onion bulb formation 8 cases of the large thickened fibers showed increased members of myelin lamellae Conclusion MS is charaterized by inflammatory demyelinating disorder limited to the CNS And some patients' peripheral neves are also shown sectionally demyelinated injury.

OBJECTIVE: To study the characteristics of infants middle ear function of children (0-1 year old) with 226 Hz, 1000 Hz tympanometry. METHOD: Tympanometric data using 226 Hz, 1 000 Hz probe tones were gained from 150 children (300 ears) aged 0-1 year old with a GSI tympstar middle ear analyzer. All of them were term birth, divided into 5 groups of 30 patients, the neonatal period (0-28 days), 6 weeks (+/- 3 days), 3 months (+/- 6 d), 6 months (+/- 6 days), 7-12 months. To analyse the middle ear function of children with 226 Hz, 1000 Hz tympanometric data. RESULT: 226 Hz,1000 Hz probe tone tympanometric data were normal for the normal group, which respectively were: 76.7%, 80%, 86.7%, 90%, 93.3%. 226 Hz, 1000 Hz detection tympanometric data were not sound normal to abnormal group, the proportion in each group were: 13.3%, 8.3%, 5.0%, 3.3%, 1.6%. The contradiction between the two groups were divided into two subgroups: 226 Hz normal, 1000 Hz unusual in the proportion of each group were 6.7%, 6.7%, 5.0%, 3.3%, 1.6%; 1000 Hz normal, 226 Hz unusual in the proportion of each group were 5.0%, 5.0%, 3.3%, 3.3%, 3.3%. CONCLUSION The sensitivity and specificity of the 1000 Hz probe tone tympanometry was better.
Acoustic Impedance Tests ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Sensitivity and Specificity