1.Management of urethral dehiscence after hypospadias repair
Wei LI ; Runji LIU ; Yuli CHEN
Chinese Journal of Urology 2000;0(12):-
Objective To investigate the cause and management of urethral dehiscence after hypospadias repair. Methods 23 cases of urethral dehiscence after hypospadias repair were reviewed.According to the location of meatus and the status of available skin, urethroplasty was performed by preputial island flap, scrotal island flap or bladder mucosa translocation. Results 23 cases were followed up from 1 to 9 years.15 cases were cured.3 developed urethral fistulae after the secondary repair, which were subsecondary closed up successfully by Thiersch procedure,4 had stricture at the anastomosis site or at the meatal stenosis , which were cured by a silastlic tube stent ( 1.5~5.0 months ). 1 had a mild penile curvature yet erection was satisfactory. Conclusions Preputial or scrotal island flap translocation should be the primary choice of secondary urethral reconstruction, whereas bladder mucosa graft is used in case of local skin deficiency.A secondary surgery should be performed by experceinced uro pediatric surgeons.
2.Postoperative defectography as a function evaluation in children of Hirschsprung′s disease
Xinguo CHEN ; Linuan GU ; Guihai LIU ; Zongyuan GUO ; Runji LIU ; Rongde WU ; Xiangtao LIN ; Chunwei LI
Chinese Journal of General Surgery 2001;0(10):-
Objective KG1This study is to evaluate defectography in postoperative defecation function of Hirschsprung′s disease (HD). KG2MethodsKG1 Between 1979 and 1993, 30 HD cases were treated operatively and followed-up by defectography. KG2ResultsKG1 Thirty cases were classified into 3 groups, according to the standard quantitative clinical scoring systems with the stooling score from 0 to 14. There were 4 cases (13%) graded as excellent (maximum score of 14) with normal bowel habit, 21 cases (70%) as good (score between 10~13) with minor continence problems, 5 cases (16 7%) as fair (score between 5~9) with marked limitations in social life. Anorectal manometry study showed that the anal resting pressure and voluntary sphincter force (maximal queeze pressure minus resting pressure) in fair group were significantly lower than that in control group( P
3.Medication adherence and clinical efficacy of inhaled glucocorticoids and leukotriene receptor antagonists in the treatment of children with bronchial asthma
Yijie CHEN ; Runji CHEN ; Zejun LIN
Chinese Journal of Primary Medicine and Pharmacy 2018;25(15):1987-1989
Objective To investigate the medication adherence and clinical efficacy of inhaled glucocorticoids (ICS) and leukotriene receptor antagonists (LTRA) in the treatment of children with bronchial asthma ,in order to provide references for treatment options.Methods From 2015 to 2016,the clinical data of 140 cases with bronchial asthma who under the age of 14 years were retrospectively analyzed.The patients were randomly divided into the ICS group and the LTRA group according to the treatment methods ,with 70cases in each group.The patients in the ICS group were given aerosol inhalation of budesonide 1 mg added to saline 3 mL,twice per day,and reduced to inhale budesonide 0.5 mg/time,2 times/day after symptom relief.The patients in the LTRA group were given montelukast sodium chewable tablets 4mg/time at bed-time,one time a day for 3 months.According to the MARS-A compliance assessment,the compliance of patients in the treatment process was graded and the therapeutic effect was analyzed . Results In the same medication adherence , the effective treatment samples ( including good control and partial control) of the ICS group were 62 cases,and 8 cases without control and the effective rate was 98.36%.In the LTRA group,the effective treatment samples were 54 cases,and 16 cases without control and the effective rate was 89.09%. There was statistically significant difference in the effective rate between the two groups (χ2=6.152,P<0.05).In the same therapeutic efficacy (51 cases effective treatment of the ICS group ,54 cases effective treatment of the LTRA group),there were 50 cases with compliance in the ICS group and 62 cases in the LTRA group.The difference in the compliance was statistically significant (χ2=7.012,P<0.05).Conclusion All of the ICS group and the LTRA group can make effective control for childhood asthma.Through statistic process data of this experiment ,we discover that under the good medication adherence condition ,all of the treatment rates and the control level of the ICS group are better than the LTRA group.In the same therapeutic efficacy ,the medication adherence of the LTRA group is superior to the ICS group.