Objective To explore the efficacy of combination medical therapy with behavior intervention on overactive bladder secondary to indwelling double J ureteral stent.Methods One hundred and seven OAB patients secondary to indwelling double J ureteral stent,with 48 males,59 females,age 27-58 (41 years old on average) were randomly divided into two groups.Group A were treated with the combination of medical therapy and behavior intervention.Group B were treated with only medical therapy.The regimen of medical therapy is tolterodine 2 mg,twice daily and alfuzosin 2.5 mg,three times daily.The patients were followed-up 1 month later and OABSS score was obtained.Results The OABSS urgency score was (3.5 ±0.9) and (0.9 ±0.2),the OABSS total score was (10.7 ±2.0) and (3.9 ±1.8),and QOL was (50.8 ± 15.9 ) and (28.9 ± 13.1 ) before and after the therapy in group A ( P ＜ 0.05 ),which showed great improvement after treatment.In group B,the urgency score was (3.4 ± 1.0) and ( 1.9 ± 0.5 ) and OABSS score was ( 10.6 ± 4.8 ) and (5.6 ± 1.7) before and after treatment,whose improvement is statistically significant ( P ＜ 0.05 ).The QOL score was ( 50.7 ± 16.1 ) and ( 39.9 ± 14.2 ) before and after treatment,whose improvement is not statistically significant (P ＞0.05).After the treatment,the difference of the improvement in urgency,total and the QOL scores between groups A and group B is statistically significant (P ＜ 0.05 ).Conclusions Tolterodine and alfuzosin can effectively alleviate overactive bladder symptoms secondary to indwelling double J ureteral stent by combining medical therapy with behavior intervention.

OBJECTIVETo explore the correlation between the content of lecithin mass and white blood cells (WBC) of the expressed prostatic secretion (EPS) and the concentration of serum PSA in patients with prostatitis, and to study the difference in serum PSA concentration between patients with bacterial prostatitis and those with nonbacterial prostatitis.

METHODSThe serum PSA concentration in 62 patients with prostatitis and 22 controls were measured with ELISA method. The correlation between the content of lecithin mass and WBC of the EPS and the elevation of serum PSA was analyzed. And the serum PSA concentration of bacterial prostatitis (9 patients) and that of nonbacterial inflammatory prostatitis (53 patients) were compared.

RESULTSThe mean concentrations of serum PSA in the prostatitis and the control groups were (1.79 +/- 0.68) microg/L and (0.63 +/- 0.29) microg/L, respectively. The difference of the serum PSA concentration was significant between the prostatitis and the control groups (P < 0.001) as well as between the groups with higher and lower WBC contents in EPS (P < 0.05), but not between the groups with higher (27 patients) and lower (35 patients) lecithin mass contents in EPS (P > 0.05), nor between the groups of bacterial prostatitis and nonbacterial prostatitis (P > 0.05).

CONCLUSIONProstatitis may cause the elevation of serum PSA concentration. The elevated serum PSA correlates with the content of white blood cells in EPS, but not with the content of lecithin mass in EPS, nor with the type of prostatitis, either bacterial or nonbacterial.

Adult ; Humans ; Leukocyte Count ; Male ; Middle Aged ; Phosphatidylcholines ; analysis ; Prostate ; secretion ; Prostate-Specific Antigen ; blood ; Prostatitis ; metabolism