1.Dose option of haemophilia prophylaxis in children.
Chinese Journal of Pediatrics 2012;50(1):70-72
2.Development of inhibitor against hemophilia and prevention and management strategies forpatients with hemophilia.
Chinese Journal of Pediatrics 2013;51(8):631-634
Blood Coagulation Factor Inhibitors
;
antagonists & inhibitors
;
blood
;
Factor VIII
;
administration & dosage
;
antagonists & inhibitors
;
immunology
;
Hemophilia A
;
drug therapy
;
genetics
;
immunology
;
Humans
;
Immune Tolerance
;
Isoantibodies
;
blood
;
immunology
;
Recombinant Proteins
;
adverse effects
;
immunology
;
therapeutic use
;
Risk Factors
;
Time Factors
3.Status of joint and intracranial bleeding of moderate and severe hemophilia in children under on-demand therapy.
Chinese Journal of Pediatrics 2012;50(8):636-638
Age Distribution
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Blood Coagulation Factors
;
therapeutic use
;
Child
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Child, Preschool
;
Developed Countries
;
Developing Countries
;
Factor VIII
;
therapeutic use
;
Hemarthrosis
;
epidemiology
;
etiology
;
prevention & control
;
Hemophilia A
;
complications
;
drug therapy
;
epidemiology
;
Humans
;
Intracranial Hemorrhages
;
epidemiology
;
etiology
;
prevention & control
;
Joint Diseases
;
prevention & control
;
Quality of Life
;
Severity of Illness Index
4.Congenital neutropenia in an infant.
Min JIANG ; Shuang YANG ; Run-hui WU
Chinese Journal of Pediatrics 2007;45(7):555-555
7.Clinical analysis of diagnosis, treatment and bleeding pattern of 129 moderate and severe preschool hemophiliacs.
Wen-wen HE ; Run-hui WU ; Xin-yi WU
Chinese Journal of Hematology 2012;33(5):420-422
Child, Preschool
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Hemophilia A
;
classification
;
diagnosis
;
therapy
;
Hemorrhage
;
diagnosis
;
therapy
;
Humans
;
Infant
9.Experiences in maintenance and repair cost control of medical equipments.
Chinese Journal of Medical Instrumentation 2005;29(4):304-305
This paper introduces methods to control the cost of maintenance and repair for medical equipments through service team training, service contract control, system establishment and outside service resources, etc..
Cost Control
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Equipment and Supplies
;
Maintenance
;
economics
;
organization & administration
10.Biological Characteristics and Mechanism of Killing Tumor of Cytokine-Induced Killer Cells
miao, LIU ; xiao-yan, WU ; run-ming, JIN
Journal of Applied Clinical Pediatrics 2006;0(15):-
Objective To investigate the cytotoxicity and mechanism of killing tumor of cytokine-induced killer (CIK) cells in vitro.Methods Mononuclear cells were acquired freshly from bone marrow of children with leukemia,and the cells obstained were induced into dendritic cells by adding granulocyte-macrophage colony-stimulating,IL-4,TNF-? and other cytokines.Lymphocytes cells were isolated freshly from peripheral blood of children with leukemia by Ficoll-Hypaque density centrifugation,and the cells obstained were induced by IFN-?,IL-2 and CD3McAb.The DC cells and CIK cells were co-cultured for 10-25 days,then DC-CIK cells were obtained.Phenotypes of DC-CIK were analyzed by flow cytomery.The cytotoxicity of DC-CIK against a variety of leukemic cell lines was investigated by MTT technique.When treated with mouse-anti-human LFA-1 monoclonal antibody,the expression of GATA-3 and T -bet in the levels of mRNA and protein were mea-sured by using RT-PCR and Western Blot technique,respectively.Results In the first 0-6 days,DC-CIK induced slowly,the proliferation of DC-CIK got 100-fold at the 13th day,cells were rapidly proliferating in the first 13-21 days.The maximum proliferation of DC-CIK reached at the 22nd day.The phenotypes of CD3,CD11a,CD54,HLA-DR were expressed highly; CD3/CD56,CD25,CD28,CD69,FasL were expressed moderately on DC-CIK.The expression of CD16 was not increased.DC-CIK possessed the cytotoxicity against tumor cells of B95,Jhhan and M07e.The effect was stronger to B95,there was no significant difference when the efficiency target ratio was 12.5:1.0 or 25:1,the cytotoxicity reached about 50% and 60%,respectively,against tumor cells of B95.However,it was not obvious to Jhhan and M07e.When the efficiency target ratio was 12.5:1.0 or 25:1,the cytotoxicity reached to 27.21%,25.13%,33.05%,29.72%,respectively,against tumor cells of Jhhan and M07e.When treated with mouse-anti-human LFA-1 monoclonal antibody,the expression of GATA-3 in the level of mRNA was up-regulated(t=3.425,4.523 Pa