Objective To study the clinical effect and surgical treatment of intestinal obstruction.Methods From January 2015 to December 2016,45 cases with intestinal obstruction who admitted to the Department of General Surgery of Taizhou First People's Hospital were selected in the research.According to the single blind randomized grouping method,the patients were randomly divided into two groups.22 cases in the control group were given conservative treatment,23 cases in the observation group received surgery.The clinical total effective rate ,abdominal pain relief time,recovery time,gas-liquid plane disappeared time ,hospitalization time and the incidence of complications were compared between the two groups.Results The clinical total effective rates of the two groups were 90.91%, 95.65%,respectively,the difference was not statistically significant (χ2＝0.407,P ＞0.05).The abdominal pain relief time,recovery time, gas -liquid plane disappeared time , hospitalization time in the observation group were significantly shorter than those in the control group (t＝4.373,4.332,3.372,3.529,all P＜0.05).The incidence rate of complications of the observation group was significantly higher than that of the control group (χ2＝4.294,P＜0.05).Conclusion Surgical treatment has significant clinical effect for patients with intestinal obstruction ,which can effectively promote the remission of symptoms ,shorten the treatment time,but with more complications ,so it need to be cautious in the choice of treatment.