1.Comparision of rivaroxaban and warfarin on preventing post-operation deep vein thrombosis in elderly hip fracture patients with diabetes mellitus
Rujun ZUO ; Huawei SONG ; Jingliang WU
Chinese Journal of Biochemical Pharmaceutics 2017;37(1):200-202
Objective To compare the clinical effects between rivaroxaban and warfarin on preventing deep vein thrombosis (DVT) in elderly hip fracture patients with diabetes mellitus (DM) after operation. Methods One hundred and sixty-eight elderly hip fracture patients with DM were randomly divided into the observation group and the control group. The observation group (88 cases) were treated with rivaroxaban (10mg, po, qd) after surgery, and the control group were treated with warfarin and low molecular weight heparin calcium for 14 days. Respectively after 7, 14, 21 and 28 days, the color doppler ultrasonography was used to examination vein blood flow and the DVT of affected lamb. In addition, the levels of D-dimer and bleeding were observed during treatment. Results The incidence of DVT in observation group (2 cases, 2.23%) was significantly lower than that in control group (7 cases, 8.75%), and DVT of control group was happened on 7th day after surgery. In addition, the level of D-dimer on 7th day post-surgery in observation group significantly decreased, while it significantly decreased on 14th day post-surgery in control group (P<0.05). However, the incidence of bleeding events in observation was less than that in control group (P<0.05). Conclusion Rivaroxaban can be more effective compared with warfarin in preventing diabetes mellitus elderly hip fracture patients with postoperative DVT formation and significantly reduce the bleeding risk, with more safe and convenient.
2.QUANTITATIVE ANALYSIS OF TISSUES CELL DNA CONTENT IN DIFFERENT POSTMORTEM INTERVAL
Fengying QI ; Shutang XU ; Rujun LIU ; Lianfu ZUO ; Jianwen GUO ;
Chinese Journal of Forensic Medicine 1988;0(04):-
Cell DNA content in heart, liver, kidney of rats were analysed by flow cytometer at different postmortem interved. The rsults show that mean cellular DNA content is 99.5% at 6 hours, 91.3% at 12 hours, 87.1% at 18 hours, 81.3% at 24 hours, 76.7% at 30 hours, 74.3% at 36 hours, 72.3% 48 hours as compared with that at o hours The results ingicates that the quantitative determination of cell DNA in the tissues, mentioned above may provide an objective and reliable approach for the estimation of postmortem time.
3.Nonoperative Treatment of Thoracolumbar Fractures without Neurological Deficit
Dong WANG ; Minglian YANG ; Lei WU ; Rujun ZUO
Chinese Journal of Rehabilitation Theory and Practice 2007;13(11):1085-1086
Objective To evaluate the clinical effect of postural reduction and bracing on thoracolumbar fractures without neurological deficit.Methods21 patients with thoracolumbar fractures(T11~L2