Objective? To explore the effects of psychological flexibility intervention on the symptoms and self-management efficacy of patients after hepatic arterial infusion chemoembolization. Methods? By convenient sampling, a total of 90 patients with hepatocellular carcinoma who had undergone hepatic arterial transcatheter chemoembolization in the First Affiliated Hospital of Zhengzhou University from January to February 2018 were selected. By random number table method, they were divided into the observation group and the control group, with 45 participants in each group. The control group received routine nursing intervention, and the observation group received psychological flexibility intervention, both for 2 weeks. Before and after the intervention, the Memorial Symptom Assessment Scale (MSAS) and the Chinese version of the Strategies Used People to Promote Health (SUPPH) were used to assess the symptomatic distress and self-management efficacy of the two groups in order to evaluate the effects of the intervention. Results? There were no significant statistical differences in the average scores of physical symptoms, psychological symptoms, distressed index, and main clauses of MSAS before intervention between the two groups(P＞0.05). After intervention, the physical symptoms of the patients in both groups had no statistical difference compared with those pre-intervention (P＞0.05), while the average scores of psychological symptoms, distress index, main clauses of MSAS were all lower than those pre-intervention with statistical significance (P＜0.05). In the observation group, the average scores of psychological symptoms, distress index, and main clauses of MSAS were lower than the control group after intervention with statistical significance (P＜ 0.01). Before intervention, the total score of SUPPH and the score from each dimension in the scale between two groups had no statistical difference (P＞ 0.05). After intervention, the total score of SUPPH and the scores from each dimension increased with statistical significance (P＜0.05) while no statistical significance was found in the control group (P＞0.05). The total score of SUPPH and the scores from each dimension were all higher than the control group with statistical significance (P＜0.01). Conclusions? The psychological flexibility intervention can effectively reduce the patients' psychological distress after chemoembolization, and promote their self-management efficiency,therefore is worth promoting in the clinical practice.

Objective:To observe the application value of virtual cognitive rehabilitation training in patients with mild cognitive impairment induced by transcatheter arterial chemoembolization (TACE) of liver neoplasms.Methods:By the convenience sampling method, a total of 126 liver neoplasms patients with mild cognitive impairment induced by TACE who were admitted and treated in the First Affiliated Hospital of Zhengzhou University from May 2015 to May 2019 were selected. They were randomly divided into the observation group and the control group, with 63 cases in each group. The control group was given routine cognitive intervention while the observation group was given virtual cognitive rehabilitation training, and the intervention lasted for 2 months. Montreal Cognitive Assessment Scale (MoCA) , Activities of Daily Living (ADL) Scale and Chinese version of Strategies Used by People to Promote Health (SUPPH) Scale were used to evaluate the cognitive function, ability of daily living and self-efficacy level of patients before and after intervention between two groups.Results:There was no statistically significant difference in MoCA, ADL, and SUPPH scale scores of patients between the two groups before the intervention ( P> 0.05) . After 2 months of intervention, the total score of the MoCA Scale (21.70 ± 5.27) and the total score of the SUPPH Scale (88.23 ± 21.43) in the observation group were higher than those in the control group, and the differences were statistically significant ( t=2.949, 4.509; P<0.05) . After intervention, the score of the ADL Scale in the observation group was (16.03±3.11) and that in the control group was (18.06±2.97) , and the difference was statistically significant ( t=3.747, P<0.05) . Conclusions:Virtual cognitive rehabilitation training can improve the cognitive function of liver neoplasms patients with mild cognitive impairment caused by TACE and improve the activity of daily living and self-efficacy.

Objective:To explore and analyze the application of smoking cessation intervention based on timing theory in elderly patients with chronic obstructive pulmonary disease (COPD) complicated with tobacco dependence.Methods:A total of 120 elderly patients with COPD combined with tobacco dependence who were admitted to the First Affiliated Hospital of Zhengzhou University from January 2020 to March 2021 were selected by the convenient sampling method. They were divided the control group and the observation group according to the random number table method, with 60 cases in each group. The control group was given routine intervention, while the observation group was given smoking cessation intervention based on timing theory. The smoking cessation rate, nicotine dependence degree, clinical symptom score and lung function recovery were compared between the two groups.Results:Three months after discharge, the nicotine dependence degree of observation group was lower than that of control group, and the difference was statistically significant ( P<0.05). The smoking cessation rates of 1, 2 and 3 months after discharge in the observation group were higher than those in the control group, and the differences were statistically significant ( P<0.05). Three months after discharge, PEF of observation group was higher than that of control group, and the difference was statistically significant ( P<0.05). The clinical symptom score of the observation group at 3 months after discharge was lower than that of the control group, and the difference was statistically significant ( P<0.05) . Conclusions:The application of smoking cessation intervention based on timing theory in elderly patients with COPD complicated with tobacco dependence can improve the smoking cessation rate, reduce the degree of nicotine dependence of patients and effectively alleviate COPD related clinical symptoms.