Objective To observe the therapeutic difference between modified blistering moxibustion and traditional blistering moxibustion in treating bronchial asthma in young adults.Method Totally 121 young adults with bronchial asthma were randomized into a treatment group of 62 cases and a control group of 59 cases. With the same points selected for the two groups, the treatment group was intervened by blistering moxibustion with modification in several aspects including columnar moxa cone, topical anesthesia in moxibustion region, application of sticking after moxibustion, and regulation of diet, while the control group was by traditional blistering moxibustion. The treatment was given once every summer, successive 3 times as a treatment course. The attack frequency and intensity were scored before intervention and after a treatment course, and the clinical efficacies were compared between the two groups.Result The attack frequency and intensity scores were significantly changed after the intervention in both groups (P<0.01). After treatment, the attack frequency and intensity scores in the treatment group were significantly different from that in the control group (P<0.01). The total effective rate and recovery rate were respectively 100.0% and 61.3% in the treatment group, versus 98.3% and 28.8% in the control group. There was a significant difference in comparing the recovery rate between the two groups (P<0.01); there was no significant difference in comparing the total effective rate (P>0.05). There were significant differences in comparing the blister parameters (blister starting time, blister scar falling-off time, pus drainage time, recovery time of the blister, and the maximum diameter of the blister) between the two groups (P<0.01,P<0.05).Conclusion Modified blistering moxibustion is an effective method in treating bronchial asthma in young adults.

Objective To explore the influence of nursing intervention on quality of life of uremic patients with restless legs. Methods 60 uremic patients with restless legs in our hospital from June 2009to December 2010 were divided into the observation group and the control group with 30 patients in each group according to the nursing method.The control group was given conventional nursing,the observation group was given strengthening sleep nursing and psychological care on the basis of the control group.The psychological status,sleep status and quality of life were compared between the two groups. Results The psychological improvement in the observation group was better than that in the control group,sleep time and insomnia proportion in the obeervation group was better than that in the control group,the score of life quality in the observation group was better than that in the control group. Conclusions Nursing intervention can improve adverse psychological state in uremic patients with restless legs,improve aleep quality and quality of life.

Objective To investigate the value of serum anti-CCP antibody and TNF-α in the diagnosis and therapeutic effect evaluation of rheumatoid arthritis(RA).Methods One hundred and sixty-eight RA patients in our hospital from January 2012 to December 2015 were selected and included 86 cases of active stage(active group)and 80 cases of remission stage(remission group).Other 80 outpatient healthy controls served as the control group.The levels of RF,anti-CCP antibody and TNF-α in the active group,remission group and control group were measured by using the immunoadsorption and ELISA.Then the detection results were analyzed.Results The serum anti-CCP antibody and TNF-α levels in the active group and remission group were higher than those in the control group,moreover the serum anti-CCP antibody and TNF-α levels in the active group were significantly higher than those in the remission group,the difference was statistically significant(P＜0.05).Comparing the RA patients with the control group,the sensitivity and specificity of combined detection of anti-CCP antibody and TNF-α was 73.8％ and 97.5％,which were higher than those of other 2-index combined detection,the difference was statistically significant(P＜0.05).The serum TNF-α level was positively correlated with the DAS28 score(P＜0.01).Conclusion The combined detection of serum anti-CCP antibody and TNF-α has an important clinical value for the RA diagnosis and disease condition monitoring.

OBJECTIVE:To study the stability of Baicalin in Biyuanling granules and predicate its validity duration. METHODS:The content of Baicalin in Biyuanling granules was determined by RP HPLC on Diamonsil ODS C_(18) chromatographic column(200 mm?4.6 mm,5?m) with methanol -water- phosphoric acid(53:47:0.2) used as mobile phase.The detective wavelength was set at 274 nm.The stability of Baicalin in Biyuanling granules was determined by classical accelerated test process in constant temperature and its validity duration was computed.RESULTS:The disintegration constant of Baicalin at 25℃was K = 4.592?10 ~6 h~1,and the validity duration was t_(0.9)=2.62 years.CONCLUSION:The method developed in this study was proved to be scientific,reasonable and suitable for the study of the stability of Biyuanling granules.

25 cases of saddle nose anaplasty with hydroxylaptite ceramics have been reported in this paper.Anaesthesia and the operating methods have been modified to make the operating ef- fects more satisfactory.All of the merits of the modification have been discussed in the paper.

Objective To analyze the epidemiological characteristics of breakthrough varicella cases in Fengxian District of Shanghai from 2007 to 2023,so as to provide a reference for the effective prevention and control of varicella epidemic.Methods The reported cases of varicella in Fengxian District of Shanghai from 2007 to 2023 were collected by China Information System for Diseases Control and Prevention.The immunization history information of varicella cases was obtained from Shanghai Immunization Program Information System and analyzed by descriptive epidemiological methods.Results A total of 2 175 breakthrough varicella cases were reported in Fengxian District of Shanghai from 2007 to 2023.The proportion of breakthrough cases in each year was from 0.64% to 36.29% with statistically significant difference(χ~2=1 144.60,P <0.01).The varicella breakthrough cases were mainly concentrated in the 3-11 age group,and the primary cases were concentrated in the 5-11 and 15-20 age groups,with breakthrough cases skewed towards younger ages.The varicella breakthrough cases were predominantly preschool children and lower-grade students,while primary cases were more common among lower-grade students and university students,displaying a statistically significant difference(χ~2=242.89,P <0.01).The incidence of varicella showed a peak during the winter season,and the highest incidence of varicella breakthrough cases occurred in 3-7 years after vaccination.Since the adjustment of varicella vaccination program in 2017,the incidence of varicella among children aged 1-6 years showed a downward trend(R=-0.009,P=0.000).Conclusion From 2007 to 2023,the proportion of varicella breakthrough cases in Fengxian District of Shanghai showed a consistent increasing trend.The continuous monitoring of varicella and publicity should be strengthened in schools and kindergartens.It is of substantial significance to strengthen immunization three years after the first dose of vaccine.The adjustment of varicella immunization program has achieved remarkable results.

The paper introduces the user demands and the concept of health management,proposes the design idea of the health management system,and develops a comprehensive health management service platform integrating functions of health registration,medical examination,health assessment,exercise and physiotherapy,and regular follow-up.It mainly describes the system architecture and major functional modules.

Objective To investigate expression change of Ku70 protein before and after radiotherapy in patients with cervical cancer, as well as its relationship with clinical characteristics. Methods Seventy cervical cancer patients who received three dimensional conformal radiotherapy combined with chemotherapy were registered. Specimens tissues were obtained from cervical tumors of irradiation dose of ≤10 Gy and ≥20 Gy group. Immunohistochemistry was used to detect the expression of Ku70 in 70 cases, and its relative expression was analyzed by image software. Results The relative expression levels of Ku70 in cervical cancer patients treated with radiation doses of ≥20 Gy group (1.31 ± 0.83) and ≤10 Gy group (0.71 ± 0.60) were significantly higher than that before radiotherapy (0.50 ± 0.19), and there was a significant difference (t=7.143, P< 0.01; t= 2.655, P< 0.05). The expression of Ku70 was related with clinical stage, differential degree and tumor diameter (all P< 0.05), but not with age and tumor type (both P> 0.05). The expression of Ku70 in radiotherapy resistant group was significantly higher than that in radiotherapy sensitive group (0.55 ± 0.24 vs. 0.25 ± 0.17, t= 2.979, P< 0.01). Conclusions The expression of Ku70 protein in cervical cancer tissues is increased with the rise of radiotherapy dose. The expression of Ku70 in radiotherapy resistant group is significantly higher than that in radiotherapy sensitive group, indicating that Ku70 protein is correlated with the radiosensitivity, clinical stage, differential degree and tumor diameter.

Objective To observe changes on those parameters on pletelet and hemoglobin of urinaemia patients by treatments of dialysis.Methods candidators are divided into three groups respectively-a control group,two case groups.The two case groups are consist of patients who are treated through dialysis on not.In the three groups,the parameters on pletelet,hemoglobin,MPV and PDW are measured on hemocytometer in our laboratory. Results Dramatic difference is made in the parameters on PLT,Hb,MPV and PDW between the formers of dialysis and the control group.(P

Purpose: To observe the clinical therapeutic effect of cold moxibustion on rheumatoid interphalangeal arthritis. Methods: 576 cases were randomly divided into 290 cases in the cold moxibustion group and 286 cases in the control group and were treated for two months. Results:There was no significant difference in the total effective rate between the two groups. But, at the end of the second course of the treatment, the complete remission rate reached 77.2% in the former group and only 23.4% in the latter group, with a significant difference between the two groups (P＜0.005).Conclusion: Cold moxibustion is better in the therapeutic effect for rheumatoid interphalangeal arthritis than anti-inflammatory agents of western medicine.