1.The value of lung ultrasound score in preterm neonatal respiratory distress syndrome
Yan LI ; Xiao HE ; Jianbo GAO ; Ruifang ZHANG ; Ruina YU
Chinese Journal of Ultrasonography 2018;27(5):423-426
Objective To investigate the value of lung ultrasound scores ( LUS ) combined with echocardiography for evaluation of the state of preterm neonatal respiratory distress syndrome ( RDS ). Methods Lung ultrasound and echocardiography were conducted on 43 preterm newborns with RDS. The echocardiographic parameter included the area and velocity of tricuspid regurgitation, patent ductus arteriosus ( PDA ) and pulmonary artery systolic pressure ( PASP ). Correlational analyses of LUS and PASP,or X-ray grading were conducted. LUS difference was compared between the groups with PDA and without PDA. Results ① There was positive correlations between LUS and PASP ( r = 0.647, P <0.05),LUS and X-ray grade ( r =0.770, P <0.05). ②LUS was significant different in different X-ray grade( F = 31.460, P < 0.05). ③ Significant difference was found between the groups with PDA and without PDA( t =3.08, P <0.05). Conclusions LUS combined with echocardiography can be used as an effective method for early diagnosis,condition assessment and prognosis of RDS,and it is more direct,fast and without radiation.
2.Ultrasonographic features and significance of scoring of lung in preterm infants
Xiao HE ; Xue MEI ; Xiuyong CHENG ; Yan LI ; Lu WANG ; Ruina YU ; Lina SHANG ; Lu DING ; Jianbo GAO
Chinese Journal of Medical Imaging Technology 2018;34(5):688-691
Objective To observe ultrasonographic features and significance of scoring of the lung in preterm infants.Methods Totally 37 preterm infants (preterm group) and 33 term infants (term group) without cardiopulmonary disease nor hypoproteinemia were enrolled,and infants in each group were divided into<1 week,1-4 weeks and >4 weeks subgroup,respectively.All the infants underwent lung ultrasonography and scoring.The ultrasonography scores were compared between preterm infants and term infants among different ages.Results The main ultrasonic manifestations of the lung in preterm infants were diffuse distribution of dense B-lines,with or without " falls sign" suggesting alveolar effusion.The ultrasonographic score of the lung in preterm infants and term infants was (15.24± 2.76) and (12.21 ±3.62),respectively (t=3.962,P<0.001).There was no statistical difference of ultrasonographyic scores in <1 week subgroups between preterm infants and term infants (t =-0.669,P =0.513).There were statistical differences of ultrasonographic scores in 1-4 weeks subgroups and >4 weeks subgroups between preterm group and term group (both P<0.05).In preterm group,the ultrasonographic scores demonstrated no statistical difference among 3 subgroups (F=0.960,P=0.393),whereas statistical difference was found among 3 subgroups in term group (F =4.277,P =0.023).The ultrasonographic score of preterm infants showed negative correlation with gestational age (r=-0.352,P=0.033),and the linear regressive equation was Y=33.805-0.548X.Conclusion The main ultrasonic manifestations of the lung in preterm infants were diffuse distribution of dense B-lines,some with "falls sign" suggesting alveolar effusion,which are more significant in smaller gestational age infants.
3.Cognitive status of Chinese acne patients and its influencing factors
Shuyun YANG ; Ying TU ; Jianting YANG ; Rong JIN ; Yanni GUO ; Xinyu LIN ; Ying QIU ; Hongxia LIU ; Yao XIE ; Yuzhen LI ; Leihong XIANG ; Bo YU ; Xianyu ZENG ; Changchun XU ; Fengyan LU ; Xing LI ; Hua DU ; Xiangfei LIN ; Yuedong QIU ; Feifei ZHU ; Yufu FANG ; Mingfen LYU ; Ruina ZHANG ; Xinlin HU ; Linjun JIAO ; Hongxia FENG ; Xiaodong BI ; Min ZHANG ; Biwen LIN ; Qiao LIU ; Yonghong LU ; Li HE
Chinese Journal of Medical Aesthetics and Cosmetology 2019;25(5):403-410
Objective To indentify the cognitive status of Chinese patients to acne and the influencing factors to theirs' cognitive status,so as to provide solid evidences for the prevention and treatment of acne.Methods A self-designed questionnaire was made to conduct this survey of 16,156 acne patients,who seeked to the treatment in the dermatological departments from 112 hospitals in China.The survey consisted of several parts,including the general status of patients,the patients' cognition of occurrence,development and risk factors of acne,whether the first choice was seeking treatment at the hospital when the patients had acne and the condition of selection of skin care products.The factors were analyzed,which could impact the cognition of the patients' behavior of treatment,how did the patients' cognition to influence their medical behavior and skin care as well as the consistency of assessment of the severity of acne by doctors and patients themselves.Results The acne patients studied had the best knowledge of "acne is a skin disease","it not only occurs in the period of adolescence" and "the disease can be prevented and cured",which accordingly accounted for 80.65%,69.16% and 65.49% of the total patients respectively.However,the awareness of acne patients to heredity,high sugar and dairy products as risk factors for acne was insufficient,which accounted for 48.72%,42.40% and 18.25% of the total patients,respectively.Gender,age,educational level,occupation and health knowledge were the main factors affecting the cognitive level of patients;the survey also found that men,patient with educational level of junior high or even lower educational condition,occupation of labor workers or farmers and patients were lack of health education with poor knowledge of the genetics and dietary were risk factors for acne;patients with age over 36 years or with mild illness had poor knowledge of dietary risk factors for acne;the difference was statistically significant (P<0.05).The analysis of the influence of cognitive status on medical treatment behavior and skin care showed that the better the cognition,the higher the probability of patients would choose medical treatment as the first choice as well as choosing functional skin care products;the difference was statistically significant (P<0.05).The consistency of assessment of the severity of acne by doctors and patients was poor (Kappa value <0.4),and the assessment of severity of acne by patients was more serious than doctors' assessment.Conclusions Patient's cognitive status will affect their medical behavior and skin care,and there is also a phenomenon that patients have a more serious assessment of their acne condition.It is suggested that health education for acne patients should be strengthened in clinical medicine so as to improve their knowledge of acne as well as preventing from acne effectively.
4.Investigation and analysis of superficial fungal infection and drug use among naval trainees
Xing ZHANG ; Ruina WANG ; Changgui WU ; Xiangyu WU ; Yu LIU ; Dazhi ZHANG ; Hua ZHONG
Journal of Pharmaceutical Practice 2023;41(10):625-628
Objective To investigate the pathogenesis of superficial mycosis among naval trainees, and observe the efficacy of a novel antifungal drug. Methods A questionnaire survey was conducted on the onset, medication and recurrence of superficial fungal infection among the trainees from January, 2020 to July, 2020. At the same time, the new antifungal drug sulconazole nitrate spray was provided for treatment and the drug efficacy was observed. Results The participants generally lacked understanding and attention to superficial fungal infections. The incidence rate of superficial fungal infection was 52%, of which 76.2% of patients had recurrence of superficial fungal infection. The sulconazole nitrate spray showed great effect against these infections. Conclusion The trainees should understand the causes of superficial fungal infection through health education and seek medical treatment and medication in time. The cure rate of superficial fungal infections could only be improved through the collaborative management of the school, hospital, and trainees to reduce the impact of these infections on naval trainees’ work and life.
5.Ethacrynic acid targets GSTM1 to ameliorate obesity by promoting browning of white adipocytes.
Zhaomeng CUI ; Yang LIU ; Wei WAN ; Yuyan XU ; Yehui HU ; Meng DING ; Xin DOU ; Ruina WANG ; Hailing LI ; Yongmei MENG ; Wei LI ; Wei JIANG ; Zengxia LI ; Yiming LI ; Minjia TAN ; Dengke K MA ; Yu DING ; Jun O LIU ; Cheng LUO ; Biao YU ; Qiqun TANG ; Yongjun DANG
Protein & Cell 2021;12(6):493-501