1.Cognitive Function in Hypertension Patients Complicated with Metabolism Diseases
Ruimin GUO ; Yanchun GONG ; Jizhen GUO
Chinese Journal of Hypertension 2007;0(05):-
Objective To Evaluate the cognitive function in essential hypertensive patients complicated with metabolism diseases. Methods Eighty five essential hypertensive patients(EH)and other seventy four essential hypertensive patients complicated with metabolic disorder (EH+MD) were enrolled. Patients of EH+MD were categorized into glucose metabolism disorder (n=27), hyperlipidemia (n=15) and gluco-lipid metabolism disorder (n=22). Cognitive function was evaluated using "Clinical memory measuring scale" and "CISA intelligence scale". Results Direction and association memory, free imaging and portrait memory were better in EH than that in EH+MD (P
2.The impact of initial periodontal therapy on the peripheral blood MMP-3 and IFN-γ levels in patients with oral lichen planus and chronic periodontitis
Huimin GONG ; Hongchi ZHANG ; Ruimin ZHANG
Journal of Practical Stomatology 2017;33(4):546-549
Objective:To investigate the significance of periodontal treatment on the levels of MMP-3 and IFN-γin the serum of patients with oral lichen planus(OLP) and chronic periodontitis(CP) before and after treatment.Methods:60 patients with erosion OLP and CP were divided into 2 groups randomly (n =30).The patients in experimental group received basic periodontal treatment combined with drug therapy,those in control group received drug therapy only.Before and after treatment the periodontal indexes of PD,AL,BI and PLI were measured in the experimental group,the levels of MMP-3 and IFN-γ in serum were tested by ELISA in the 2 groups,the differences of the data between 2 groups were statistically analysed.Results:After treatment the periodontol indexes were decreased in the experimental group(P < 0.05),the serum MMP-3 and IFN-γ levels were lower than those before treatment in 2 groups(P<0.05),and the decline of MMP-3 and IFN-γ in experimental group was more obvious than those in the control group (P<0.05).Conclusion:Periodontal initial therapy has positive influence on the treatment of OLP and can reduce the level of inflammation.
4.An innovative method of uretero-ileal anastomosis:magnetic anastomosis based on rabbit models
Miaomiao ZHANG ; Jiahui WAN ; Ruimin GONG ; Qiuye ZHONG ; Yi LYU ; Xiaopeng YAN
Journal of Modern Urology 2025;30(4):339-342
Objective: To investigate the feasibility of magnetic anastomosis for uretero-ileal anastomosis using experimental rabbit models. Methods: Six experimental rabbits were used as the models.The lower part of the left ureter was cut with scissors,the daughter magnet (DM) was placed in the middle of the ureter,and the distal end of the ureter was ligated.After that,the ileum wall was opened,the parent magnet (PM) was inserted through it,the positions of the PM and DM were adjusted so that their ends were attracted to each other,and then ileum wall incision was sutured.The operation time,intraoperative blood loss,postoperative complications and magnet discharge time were recorded.Two weeks after operation,left ureterography was performed to obtain the specimens of the uretero-ileal anastomosis,and to observe the patency of the anastomosis.The formation of the anastomosis was observed with naked eyes and light microscope. Results: Uretero-ileal magnetic anastomosis was performed successfully in 6 experimental rabbits.The operation time was 28-39(32.50±3.94) min,and the intraoperative blood loss was less than 5 mL.The rabbits recovered well after operation,and no complications were observed.All animals survived to the end point of observation.The disconnection time of magnet after operation was 9-13(10.83±1.72) days.The gross specimen showed that the anastomosis was patent.The histological observation showed that the mucosa of the anastomosis was continuous and smooth,and the anastomosis was well formed. Conclusion: Magnetic anastomosis is feasible for uretero-ileal anastomosis with simple operation and good anastomosis formation.After further experimental verification,this technique is expected to be used in clinical practice.