1.A preliminary evaluation of dermoscopy in the diagnosis of facial actinic keratosis
Ruilong GU ; Xiaodong CHEN ; Lixiong GU
Chinese Journal of Dermatology 2010;43(11):770-772
Objective To evaluate the diagnostic ability of dermoscopy in facial actinic keratosis.Methods Forty patients with facial lesions suspected for actinic keratosis were enrolled from April 2009 to November 2009. There were 27 males and 13 females among these patients aged from 46 to 88 years. The disease course varied from 2 to 20 years. Lesional specimens were obtained from the subjects and underwent dermatoscopic and histopathologic examinations. The sensitivity, specificity and consistency with pathology were calculated for dermoscopy in the diagnosis of nonpigmented facial actinic keratosis. Results The sensitivity, specificity, Youden index and Kappa index of dermoscopy were 90.91%, 88.89%, 79.80% and 0.798(χ2 = 0.25, P >0.05) respectively in the diagnosis of facial nonpigmented actinic keratosis made by one dermatologist,86.36%, 94.44%, 80.80% and 0.800 (χ2 = 0.25, P > 0.05) respectively in that made by another dermatologist.Conclusion There is a high consistency between dermoscopy and histopathology in the diagnosis of facial nonpigmented actinic keratosis.
2.Effect of balance training relying on tilted table on diaphragmatic function in patients with prolonged disorder of consciousness
Li LIN ; Ranran XING ; Jing GU ; Ruilong HUANG ; Yanyan ZENG ; Huai HUANG
Chinese Journal of Neuromedicine 2024;23(9):918-924
Objective:To observe the rehabilitation effect of balance training relying on tilted table on diaphragmatic function of patients with prolonged disorder of consciousness (pDoC).Methods:A prospective study was performed. Thirty patients with pDoC were enrolled from Department of Hyperbaric Oxygen Medicine and Rehabilitation, General Hospital of Southern Theater Command of PLA from May to December 2023. The pateints were divided into study group ( n=15) and control group ( n=15) according to different rehabilitation. Patients from the control group received conventional rehabilitation, while those in the study group received passive balance training relying on tilted table in addition to conventional rehabilitation. Diaphragmatic ultrasound examination was performed before treatment, and 4 and 8 weeks after treatment to measure diaphragm excursion (DE), diaphragm thickening inspiration (DTei), diaphragm thickening expiration (DTee) and diaphragm thickening fraction (DTF) so as to assess the diaphragmatic functions of patients with pDoC. Results:During treatment, 2 patients dropped out from the study group resulting from the willing of the family members, ultimately including 13 and 15 patients in the study and control groups, respectively. (1) Between-group comparison: no significant difference in DE, DTei, DTee or DTF was noted between the study group and control group 4 weeks after treatment ( P>0.05). However, 8 weeks after treatment, the study group had statistically increased DE, DTei and DTF compared with the control group ([1.65±0.32] cm vs. [1.21±0.22] cm; [2.07±0.26] cm vs. [1.83±0.26] cm; and [24.39±3.19]% vs. [18.93±2.50]%). (2) Within-group comparison: both group had significantly increased DE 4 and 8 weeks after treatment compared with those before treatment ( P<0.05); in the study group, DE 8 weeks after treatment was significantly increased compared with that 4 weeks after treatment ( P<0.05). No significant difference in DTei, DTee or DTF was noted in both groups between 4 weeks after treatment and before treatment ( P>0.05). In the study group, DTei, DTee and DTF 8 weeks after treatment were significantly higher than those before treatment and 4 weeks after treatment ( P<0.05). Conclusion:Balance training relying on tilted table is feasible and effective in improving diaphragmatic function in patients with pDoC, and the effect is positively correlated with treatment time within a certain time.