Successful implementation of TCM scientific research projects is the main motive force of the development of traditional Chinese medicine. With the establishment of public welfare industry research in 2006, TCM scientific research projects have obtained increasing investment funds from the central budget. Therefore, how to organize TCM research projects becomes a new task for department of scientific research management. Through years of work experience in scientific research management, the authors made an analysis of the special project management paradigm in Chinese medicine industry from the basic situation of TCM industry, investment, organization and management, and appraisal mechanism.

Nowadays, the research performance evaluation in Traditional Chinese Medicine (TCM) is basically exploring the principles and rules. What become the problems are that what index system can fully reflect the TCM performance evaluation, and what method can reflect the characteristics of TCM performance evaluation. Analyzing the status of the Korean research performance evaluation, we briefly disseminated how to establish the TCM performance evaluation.

Objective To analyze the main influencing factor of ulcerative colitis (UC).Methods Literature retrieval was conducted by using English databases (PubMed,Cochrane and Embase) and Chinese databases (CNKI,Wanfang,SinoMed and VIP) to collect the studies on the influencing factors of UC published both at home and abroad from January 2000 to October 2014.According to the inclusion and exclusion criteria,data were extracted and methodological quality was assessed.Then,a Meta-analysis was performed with Stata 12.0 software.Results A total of 24 casecontrol studies were included,involving 5 653 patients and 20 218 controls.The results of Meta-analysis showed that the influencing factors of UC would include family history of inflammatory bowel disease,ex-smoker,gastrointestinal infections,regular consumption of milk,fat diet,appendectomy,smoking and high educational level,with the pooled OR values as 4.68 (95％ CI:3.59-6.11),1.81 (95％CI:1.58-2.09),5.10 (95％CI:2.38-10.92),2.26 (95％CI:1.65-3.09),2.21 (95％ CI:1.49-3.27),0.40 (95％ CI:0.32-0.51),0.44 (95％ CI:0.32-0.60) and 0.50 (95％ CI:0.36-0.69),respectively.Conclusion Current evidence showed that the risk factors influencing the incidence of UC were family history of inflammatory bowel disease,ex-smoker,gastrointestinal infections,regular consumption of milk and fat diet,whereas appendectomy,smoking and high educational level were protective factors for UC.

ObjectiveThis study explored the application of Yiqi Zengmian prescription as a vaccine adjuvant， aiming to provide a new scheme for the prevention and control of corona virus disease 2019（COVID-19） with traditional Chinese medicine （TCM）. By analyzing the compatibility and efficacy， this paper examines the compatibility effect of Yiqi Zengmian prescription， which is modified from the classic tonifying agent Si Junzitang， as a vaccine adjuvant. MethodUsing the Database of Ancient Classical Prescriptions， this paper analyzed the composition of Yiqi Zengmian prescription and probed into the theoretical basis for the compatibility of this prescription from the properties， medicine combination， and efficacy. Furthermore， the compatibility effect of this prescription with vaccines was analyzed. ResultAs a TCM prescription， Yiqi Zengmian prescription focuses on the lung and spleen and enhances the Qi in the two organs. The lung governs Qi movement. The body breathes fresh air through the lungs and exchanges the turbid gas in the lungs， and the gas circulates alternately in the lungs to ensure the normal breathing of the human body. The spleen governing transportation and transformation is the hub for Qi movement， and Qi is the embodiment of metabolic function. By regulating qi movement and enhancing the functions of Qi and blood， Yiqi Zengmian prescription can enhance the immunogenicity of the vaccine， which provides a theoretical basis for enhancing the immune effects of vaccines. ConclusionYiqi Zengmian prescription has the effects of replenishing Qi and invigorating spleen， regulating Qi and drying dampness， and enhancing immunity. The in-depth analysis of the TCM theory of Yiqi Zengmian prescription as a vaccine adjuvant and the results of clinical and laboratory studies suggest that Yiqi Zengmian prescription may enhance the induction of immune response after vaccination and maintain the immune memory. However， the mechanism of Yiqi Zengmian prescription in regulating the complex immune network remains to be elucidated.