1.Research progress of modern psychotherapeutic devices
International Journal of Biomedical Engineering 2013;36(4):254-256,后插1
Lacking of objective referential data resources,current domestic psychotherapeutic practice is mainly based on verbal communications and associated subjective means,which elucidates the limitations to its effectiveness including discrepancies between individual patients and low repeatability.With modern technological advancement,psychotherapeutic devices have been invented to change this situation.This paper gives review of the development in this field,and proposes a practical categorization method.Besides,further development of this area is prospected.
2.Giving full play to the function of archive administration in the construction of the hospital
Lin YANG ; Ruijuan FENG ; Shi CHEN
Chinese Journal of Hospital Administration 1996;0(10):-
The archives of a hospital are a kind of intangible assets of the hospital and archive administration in a hospital constitutes an important part of the hospital's management. It can be seen from the forming process and contents of the archives in a hospital that strengthening archive administration is beneficial to the modernized and scientific management of the hospital, the improvement of medical quality and service level, the spread and application of medical science and technology, and the safeguarding of the interests of both the hospital and patients. To give full play to the function of the archives in the construction of the hospital, it is imperative to attach importance to the fundamental work concerning archives, set up the concept of archive development and application, and improve the quality of the contingents of archive administrators. Only in this way can we meet the needs of the era of knowledge economy.
3.Effects of Astragalus polysaccharide on proliferation and Akt phosphorylation of the basal-like breast cancer cell line.
Meina YE ; Hongfeng CHEN ; Ruijuan ZHOU ; Mingjuan LIAO
Journal of Integrative Medicine 2011;9(12):1339-46
To investigate the effects of Astragalus polysaccharide (APS) on proliferation of basal-like breast cancer cell line MDA-MB-468 cells and Akt phosphorylation in MDA-MB-468 cells.
4.Expression of CXC chemokine receptor 7 in atherosclerotic ApoE-defi-cient mice and therapeutic impact by atorvastatin
Xiaoli TU ; Qi CHEN ; Hongzhou ZHANG ; Ruijuan YAN ; Yanqing WU
Chinese Journal of Pathophysiology 2015;(12):2209-2215
AIM:To evaluate the expression level of CXC chemokine receptor 7 (CXCR7) in atherosclerotic apolipoprotein E-deficient ( ApoE-/-) mice induced by high-fat diet ( HFD) and the effects of atorvastatin on it .METH-ODS:ApoE-/-male mice (8-week-old) were used and were randomly divided into 3 groups following 1-week normal ro-dent diet:normal diet control (NDC) group , HFD group and HFD+statins (HFD+Sat) group.HE staining and oil red O staining were used to observe the atherosclerotic lesion burdens in the aortas .The expression of CXCR7 on the aortas was detected by Western blot and immunohistochemistry .The expression of Akt and endothelial nitric oxide synthase ( eNOS) in the aorta was determined by Western blot .RESULTS: Few lesions were found in the aortas in NDC group .Apparent atherosclerotic plaque burdens were seen in HFD group and HFD +Sat group, while the atherosclerotic plaque burdens in HFD+Sat group were notably reduced compared with HFD group .The protein levels of CXCR7, eNOS and Akt in aorta in HFD group and HFD+Sat group were significantly decreased compared with NDC group , while those in HFD+Sat group were increased compared with HFD group .The protein level of p-eNOS in the aorta and the concentration of NO in the plas-ma in HFD group were decreased compared with NDC group and HFD +Sat group.CONCLUSION: In ApoE-/-mice, HFD increases the lipid level and promotes the development of atherosclerosis by downregulating the expression of CXCR 7, Akt and eNOS.Atorvastatin reverses the above effect of hypercholesterolemia on the expression of CXCR 7, Akt and eNOS, thus playing the role in treating atherosclerosis .
5.Research Status and Developing Trends of the Electrical Impedance Imaging by Magnetic Means
Gang LI ; Ruijuan CHEN ; Liling HAO ; Ling LIN
Chinese Journal of Medical Physics 2010;27(2):1788-1792
Purpose: To obtain more precise Electrical Impedance Tomography, the conductivity imaging which utilizes the in-formation of magnetic field has been developed as new approaches of EIT. Methods: Analysing the basic theory and develop-ing status of MIT, MD-EIT and MREIT, the Electrical Impedance Imaging by magnetic means was proved to have more bright applicational prospect. Results: Based on different imaging methods, the Electrical Impedance Imaging by magnetic means can give more accurate conductivity distributions. Conclusions: The Electrical Impedance Imaging will be used more widely by magnetic means.
6.Magnetic Detection Electrical Impedance Tomography and its Application in Three Dimensional Localization of the Meridian
Ling LIN ; Liling HAO ; Ruijuan CHEN ; Gang LI ; Jiaxing LI
Chinese Journal of Medical Physics 2010;27(2):1793-1798
Objective: The Meridian Theory is an important component and the theory basis of Traditional Chinese Medicine. Three dimensional localization is the key to research of the Meridian Theory. Imaging is a scientific and practical method for the three dimensional localization of the meridian. Methods: The methods and actuality of the intrinsic quality and localization of meridians were first introduced. Then the methods and disadvantages of electrical impedance tomography (EIT) were also re-viewed. Based on these, the advantages and disadvantages of various methods applying to localization of meridian were analy-sised. Results: A new technology, magnetic detection electrical impedance tomography (MD-EIT) has obvious advantages com-paring to other EIT methods. It can fit comfortably on the dimentional localization of the meridian. Conclusions: MD-EIT can be applied not only to locate the meridians, but also to heart and lung detection and cancer diagnosis. There is a wide range of appli-cations for MD-EIT in medicine, It has great space for development.
7.Analysis of Three Treatment Regimens and Pharmaceutical Care in One Patient with Lipoprotein Glomeru-lopathy
Ruijuan WU ; Fang ZENG ; Yong HAN ; Lin MA ; Dongsheng CHEN
China Pharmacist 2014;(11):1927-1928,1986
Objective:To provide reference for the treatment of lipoprotein glomerulopathy and to investigate the participation of clinical pharmacists in the whole treatment course. Methods: Three different treatment regimens, including immunosuppressive thera-py, dual plasma filtration therapy and lipid-lowering combined with reducing urinary protein therapy was respectively adopted for one patient with lipoprotein glomerulopathy, and the efficacy was evaluated. Clinical pharmacists assisted physicians in deciding treatment regimen, performed pharmaceutical care, adjusted medication and analyzed the prognosis of the patient during the follow-up. Results:1. Immunosuppressive therapy was ineffective for the patient;2. The dual filtration acted quickly, while the expense was high and the disease was easy to relapse;3. The third therapy was relatively safer and more economical with long-term effect. Conclusion:Combi-nation therapy of lowering lipid and reducing urinary protein is the most suitable treatment regimen for the patient with lipoprotein glo-merulopathy. Clinical pharmacists play an important role in the whole course of treatment to assist physicians in obtaining the maximum benefit of patients.
8.Influences of silk fibroin on the compressive strength and injectability of calcium phosphate cement
Xiaoqing CHEN ; Huilin YANG ; Minfeng GAN ; Ruijuan XIE ; Liang CHEN ; Xuesong ZHU ; Genlin WANG ; Yong GU
Chinese Journal of Tissue Engineering Research 2008;12(45):8985-8988
BACKGROUND: High molecular materials have been proved to enhance the mechanical properties of calcium phosphate bone cement, as well as attenuate the injectability of composite materials. It thereby influences the clinical application of composite materials.OBJECTIVE: To observe the compressive strength and injectability of silk fihroin compound calcium phosphate bone cement, to evaluate the effect of silk fibroin on calcium phosphate, and to investigate the feasibility of applying silk fibroin as an injectable hone substitute to repair hone defects.DESIGN, TIME AND SETTING: Controlled study was performed in the central laboratory of Analysis and Testing Center, Soochow University from September to December in 2007.MATERIALS: Calcium phosphate cement was purchased from Shanghai Rebone Biomaterials Co., Ltd; silk fibroin was offered by Institute of Material & Engineering, Soochow University.METHODS: Six groups were set with different mass fractions (0.5%, 1%, 1.5%, 2%, 2.5%, 3%) of silk fibroin, which were mixed with bone cement at a certain liquid/solid ratio of 0.4 mL/g to prepare the calcium phosphate composite. The calcium phosphate cement without silk fibroin was served as control group.MAIN OUTCOME MEASURES: The compressive strength and injectability were determined. The characteristic microstructure was observed using scanning electron microscope.RESULTS: The compressive strength increased firstly and then decreased with the addition of silk fibroin. The compressive strength of the experimental groups was remarkably higher than the control group when the silk fibroin content was 1%-2.5% (P<0.05). The injectability of the paste diminished with the addition of silk fibroin, which was statistically different when the silk fibroin content was 1.5%-3% (P<0.05). Scanning electron microscope result revealed that the silk fihroin penetrated throughout calcium phosphate crystals, which were tightly connected.CONCLUSION: Silk fibroin can improve the compressive strength of silk fibroin/calcium phosphate cement composites without significant influence of manipulation, and can widen the application field of calcium phosphate bone substitute.
9.Investigation of working situation of community nurses and care needs of the residents in a prefecture-level city
Lifen CHEN ; Zhenlu ZHANG ; Ruijuan CHEN ; Ping YU ; Huanxin HUANG ; Landi WU
Modern Clinical Nursing 2013;(1):17-19,20
Objective To survey the working situation of community nurses and care needs of the residents in a prefecture-level city.Method One hundred and thirty-five community nurses and 338 residents were selected and investigated by self-designed questionnaire.Results Community nurses still focused on the area of nursing and treatment rather than prevention,rehabilitation, health care,health education and family planning,which need to be paid more attention to.The needs of residents on community nursing service shift from disease treatment to disease prevention and health promotion.The current community nursing service cannot satisfy residents’care needs.Conclusion Community nurses should provide demand-oriented community care to the residents, strengthen the concept of disease prevention and health promotion,and set up community health centers to be a blend of prevention, health care,rehabilitation,health education and family planning as soon as possible.
10.Risk factors of brain injury in very low birth weight infants
Qiuping LI ; Jieting HUANG ; Jia CHEN ; Ruijuan WANG ; Ying CHEN ; Junjin HUANG ; Zhichun FENG
Journal of Clinical Pediatrics 2010;(3):215-219
Objective To investigate the incidence and high risk factors of brain injury in very low birth weight infants(VLBWI),to reduce the morbidity of brain injury,and improve the developmental outcome of VLBWI. Methods Data of 181 VLBWI admitted in the neonatal intensive care unit(NICU)between October 2008 and September 2009 were retrospectively analyzed. The difference in basic information,maternity diseases,treatment and complication were analyzed between two groups(brain injury group and normal newborn group),and Logistic regression analysis was adopted to analyze the risk factors for brain injury. Results Seventy-eight of the 181 neonates(43.09%)were found to have brain injury,including 67 neonates(37.01% )with periventricular/intraventricular hemorrhage(43 with intraventricular hemorrhage(IVH)gradeⅠ,12 with IVH grade Ⅱ,10 with IVH grade Ⅲ,and 2 with IVH grade Ⅳ)and 12 neonates(6.63%,one complicated with IVH grade Ⅲ)with periventricular leukomalacia. The younger the gestational age,the higher the brain injury rate was observed. Concerning the brain injury rate,there were no differences in gender,single birth/plural births,birth weight,the mode of delivery,fetal distress,premature rupture of membrane,hypertension during pregnancy,placenta abruption,and intrauterine growth restriction(IUGR)between these two groups(P > 0.05). The difference in therapeutic measures such as pulmonary surfactant therapy,nasal continuous positive airway pressure(nCPAP),conventional mechanical ventilation,and high-frequency oscillatory ventilation was significant(P < 0.05),except aminophylline therapy(P > 0.05). As to the complication,there were significant differences in the incidences of asphyxia,neonatal respiratory distress syndrome(NRDS),hypercapnia,metabolic acidosis,hyperglycemia,anemia,and personal digital assistant(PDA)(P < 0.05). However,there was no difference in the incidences of hypoglycemia,sepsis,thrombocytopenia,apnea,pulmonary hemorrhage,and hyperbilirubinemia between these two groups(P > 0.05). Further Logistic regression analysis showed that NRDS,high-frequency oscillatory ventilation,and PDA were the main risk factors for brain injury in VLBWI. Conclusions VLBWI is the high-risk population of brain injury. Pulmonary surfactant therapy,nCPAP,conventional mechanical ventilation,high-frequency oscillatory ventilation,asphyxia,NRDS,hypercapnia,metabolic acidosis,hyperglycemia,anemia,and PDA were confirmed to be the high-risk factors for brain injury in VLBWI. And,NRDS,high-frequency oscillatory ventilation and PDA were main risk factors.