Through G protein coupling and intracellular signal transmission, opioid peptides and its receptors in myocardial tissues participate in IPC have the function of early and delayed protection. The molecular mechanism of ”trigger-regulatory medium-effector” is of great significance in the study of the pathogenesis of IPC, as well as exploring the new idea for CHD prevention and cure.

Some patients with atrioventricular nodal reentrant tachycardia(AVNRT) manifest “smooth” av node function curves. This review summarizes the essence,the end point of radiofrequency catheter ablation and the influence of some electrophysiological data in this AVNRT.

Objective:To explore therapeutic effect of rehabilitation intervention on patients with diabetes mellitus (DM)complicated tuberculosis (TB).Methods:A total of 108 DM + TB patients treated in our hospital from Jan 2008 to Aug 2013 were enrolled.According to random number method,they were randomly and equally divided into rehabilitation intervention group and routine treatment group.The intervention course was eight weeks,and then rehabilitation effect was compared between two groups.Results:Compared with before treatment,after treatment, there were significant reductions in fasting blood glucose (FBG)and 2h postprandial blood glucose (2hPBG)in both groups,P <0.01 all;compared with routine treatment group,after treatment,there were significant reductions in levels of FBG [(6.77±1.82)mmol/L vs.(5.54±1.46)mmol/L]and 2hPBG [(7.94±1.83)mmol/L vs.(6.87 ±1.42)mmol/L],P <0.01 both,and significant rise in percentages of significant reduced or disappeared pleural effusion (51.85% vs.83.33%)and significant reduced or closed TB focus (44.44% vs.72.22%)in rehabilitation intervention group,P <0.01 both.Conclusion:Rehabilitation intervention can make patients get better control of blood glucose,promote absorption of pleural effusion and pulmonary tuberculosis focus.

Objective:To assess the therapeutic effects and adverse reactions of MS Contin in the treatment of acute myocardial infarction (AMI). Methods: 42 AMI patients were divided into experiment group and control group. Experiment group were given oral administration of MS Contin for 1 week besides the routine treatment of AMI for patients in the control group. Results: Between the two groups, the differences in the product of heart rate and blood pressure ( HR?BP) , the frequency of angina pecto-ris attack, the recovery time of the ST segment and the incidence of acute arrhythmia were significant. The most common side effects observed were: vomiting, constipation, hallucination, and the most severe toxic side effect was respiratory inhibition. Conclusion : In the treatment of AMI, MS Contin could relieve the pain effectively, reduce the incidence of angina pectoris attack and severe arrhythmia, decrease myocardial oxygen consumption, have tolerable side effects in the majority of patients. It is preferable to use MS Contin as a concurrent treatment of AMI.

The placement of stent in coronary artery reduces the restenosis rate of percutaneous transluminal coronary angioplasty(PTCA),but the restenosis has perplexed us so far. May be a novel drug coated stent will bring us a new hope in the coming years.

Cardiac complications(cerebral-cardiac syndrome) very often induced by acute traumatic brain injury include abnomal ECG, decreased myocardial contractile function, increased myocardial enzymes and pathological changes etc. In order to better understand the cerebral-cardiac syndrome related to the traumatic brain injury, the major clinical features, mechanism and clinical significance are reviewed.

Objective:To investigate plasma contents of ?-endorphin(?-EP) in patients with coronary heart disease(CHD) and study the relationship between myocardial function and ?-EP in these patients.Methods:At 12,24,48,and 96 h and 7 d after episode,the plasma levels of ?-EP were measured by immunoradiometric assay(IRMA).The left ventricular ejection fraction(LVEF) was measured with echocardiography and the class of cardiac function was assessed according to NYHA. Results:The plasma levels of ?-EP in 58 patients with CHD were higher than those in 20 healthy subjects(P

Objective To investigate the ultrastructural changes of retinal pigment epithelium (RPE) and its permeability in spontaneously hypertensive rats (SHR) and explore the relation between these changes and hypertensive retinopathy. Methods The ultrastructure of RPE cells in the SHR aged five、six、seven months was observed with transmission electronmicroscope and compared to its normotensive control strain(WKY) with the same age.Then, lanthanum tracer procedures were carried out to investigate pathological changes of the blood retinal barrier. Results ①In SHR the main pathological changes involved swelling of mitochondria, enlargement of endoplasmic reticula,decrease of RPE cell infolding, and sparseness of microvilli. These degenerations were more serious in older rats with higher blood pressure.②The breakdown of outer blood retinal barrier with permeation of lanthanum tracers were evident in SHR aged six or seven month, however, in WKY and five month SHR the traces were preven ted from passing by tight junctions. Conclusion The degeneration of RPE owing to ischemia and anoxia arises in early period of hypertensive retinopathy. The pathological changes of ultrastructure and permeability might interact with the damage of visual cells and play a main role in the hypertensive retinopathy.

Objective: To observe the effect of carboxyl-amino-polysaccharide on the gastric ulcer. Methods: Various rat models of gastric ulcer were established respectively by ethanol, aspirin, hydrochloric acid, acetic acid and bound stress in water bath. Results: Inhibitory rates of carboxyl polysaccharide in the dose of 0.5, 0.33, 0.17g/kg were 42.09%, 35.55%and 33.53%for the ethanol-induced model; 53.65%, 49.48%, and 49.76%for the aspirin-induced model; 51.48%, 44.09%, and 33.64%for the hydrochloric-acid-induced model, 49.44%, 46.23%, and 45.10%for the acetic-acid-induced model and 50.12%, 44.63%and 41.92%for the bound-stress-induced model respectively. Conclusion: Carboxyl-amino-polysaccharide can prevent and treat gastric ulcer. Its effect is similar to that of denol, famotidine and cimetidine.

Capsules ; Drugs, Chinese Herbal ; Hepatitis B, Chronic ; Humans ; Liver Cirrhosis