Nutritional risk is present in a large proportion of infants with congenital heart disease,which is associated with various factors including malnutrition,pulmonary hypertension,and hemodynamic instability.Standard perioperative nutrition support may effectively decrease nutritional risk and has become an essential part in clinical treatment of congenital heart disease.Understanding the rules of perioperative energy metabolism is key to nutrition support.This article reviews the progress of research on the energy metabolism in infants with congenital heart disease in perioperative period,aiming to provide evidence for clinical nutrition support in this group of patients.

Objective To discuss the rescuing process and the selection of operating method of 9 cases of patients with carot-id artery injury .Methods 9 patients received positive anti -shock treatment after admission .Anterior sternocleidomastoid incision was made in the upper and middle section , and cervicothoracic incision was made in the lower section .Then ligature of external carot-id artery and repair and danastomosis of common carotid artery and internal carotid artery were examined .Results Among the 9 ca-ses, 2 were dead, 1 had hemiplegic paralysis and aphasia , 1 had hoarseness and drink cough and 5 others were cured.Conclusion Early diagnosis , effective haemostasis , reconstruction of carotid artery and necessary brain protection are the key to reducing the mor -tality and decreasing the morbidity of neurological deficit .

Objective To develop autosomal SNP fluorescent-multiplex PCR system,and investigate the allele frequencies of these 13 SNP loci in Southern Liaoning Han population.Methods After selected 13 autosomal SNP loci,SNP fluorescent-multiplex system was developed based on the principle of fragment length discrepant allele specific PCR,and the allele frequencies of these SNP loci in Southern Liaoning Han population were investigated using the established system.Results For the same SNP locus,the homozygote showed a single product peak,and the heterozygote showed two product peaks with different length.For the different SNP loci,the lengths of their PCR products were different.Therefore,we could genotype the 13 SNP loci simultaneously according to the length of products and the amount of product peaks,and the results were in accordance with that of direct sequencing.In the meanwhile,the allelic frequencies of these 13 SNP loci in Southern Liaoning Han population were obtained.Conclusion The SNP fluorescent-multiplex system based on the fragment length discrepant allele specific PCR strategy is simple and economical,and is of a high application value in forensic medicine.

Objective:To establish the core competency index system for emergency rescue of infectious diseases among military advance nurses, so as to provide a reference for evaluating the core emergency capability of military advanced nursing staff.Methods:The index system of emergency core competence of military advanced nursing staff in the emergency of infectious diseases was preliminarily formulated. Based on the evidence-based theory, the improved Delphi correspondence method was used to issue two rounds of questionnaires to 20 authoritative experts. After sorting out and analyzing, the effective questionnaire was formed, and the weight of each index was calculated by AHP.Results:The recovery rates of the two rounds of expert questionnaire were 100%, and the expert authority coefficients were 0.792 and 0.846, respectively; the Kendall ′s W was close to 1, which was statistically significant ( P < 0.01). Finally, three first-class indicators, 12 second-class indicators and 52 third-class indicators were determined, including knowledge related to the prevention of sudden infectious diseases, professional nursing skills and medical support capacity. Conclusion:The results show that the index content of the core emergency rescue capability system of military advanced nursing staff is centralized, the weight distribution is reasonable and has high practicability, which is conducive to improve the practical technical ability and core emergency ability of the military advanced nursing staff, improve the emergency rescue level of infectious disease emergencies and the overall medical support level of military hospitals

BACKGROUND:Genetic studies have shown that there may be association between osteoprotegerin gene G1181C polymorphism and bone mineral density in postmenopausal women, but there are some differences in the conclusions.
OBJECTIVE:To study the association between osteoprotegerin gene G1181C polymorphism and bone mineral density in postmenopausal women through Meta-analysis.
METHODS:The PubMed database, Embase database, CNKI database and Wanfang database were searched for the observational studies about the association between osteoprotegerin gene G1181C polymorphism and bone mineral density in postmenopausal women. The standardized mean difference was considered as the effect indicator and calculated with random or fixed effect models according to the significance of heterogeneity.
RESULTS AND CONCLUSION:A total of 9 articles were included with a total of 8 799 and 9 365 participants for which vertebral and spine bone mineral density had been measured, respectively. The analysis results showed that the bone mineral density of the postmenopausal women with the G al ele of G1181C was significantly lower than that of the postmenopausal women with the C al ele. Similar results were obtained in Caucasian population subgroup analysis. The Caucasian population subgroup analysis showed that the bone mineral density of the postmenopausal women with GG genotype of G1181C was lower than that of the postmenopausal women with GC and CC genotype. The results indicate that there is association between osteoprotegerin gene G1181C polymorphism and bone mineral density in postmenopausal women, and G al ele is a risk factor for lower bone mineral density.

Objective To investigate the therapeutic effect of acupoint massage combined with moxibustion on urinary retention after spinal cord injury. Methods A total of 81 cases with urinary retention after spinal cord injury hospitalized in the Second Affiliated Hospital of Heilongjiang University of Chinese Medicine from February 2016 to February 2017 were recruited in the study using random sampling method. Patients were randomly divided into the control group (42 cases) and the intervention group (39 cases). Both groups were given routine rehabilitation therapy and nursing care, and the intervention group received additional acupoint massage combined with moxibustion therapy. The clinical efficacy, the autonomous urination time and the incidence of complications of patients were compared between two groups. Results After the treatment, the clinical efficacy in the intervention group and the control group were 92.3% and 68.2% respectively, with statistically significant difference between two groups (χ2=9.42, P=0.01). The autonomous urination time of patients in the intervention group was (23.10±2.92) d, which was significantly shorter than that in the control group (P<0.001). The number of urinary tract infection cases in the intervention group was lower than that in the control group; there was no statistically significant difference between two groups (P>0.05). Conclusions The application of acupoint massage combined with moxibustion in patients with urinary retention after spinal cord injury has good effects and is worthy of clinical promotion.

Objective To explore the clinical effects of warming needle moxibustion on lower limbs arteriosclerosis obliterans of blood stasis type. Methods From September 2015 to September 2017, we selected 60 patients from the First Affiliated Hospital and the Second Affiliated Hospital, Heilongjiang University of Chinese Medicine. All of the patients were divided into control group and intervention group with the randomized control method, 30 cases in each group. Patients of control group were treated with Huo Xue Tong Mai Yin decoction. Patients of intervention group accepted warming needle moxibustion and Huo Xue Tong Mai Yin decoction. We compared the clinical effects, diameter and blood flow parameters of lower extremity artery, the expression of nitric oxide (NO) and endothelin (ET) between two groups before and after treatment. Results Clinlcal symptoms of patients between two groups all relieved in different degrees. For example, pain eased; the temperature of lower limb got warm again; the dull-red and pale colour weakened; the number of walk and qi-blood increased; the improvements of the symptoms in intervention group were better than those in control group with significant differences (P<0.05). The improvements of diameter and blood flow parameters of lower extremity artery in intervention group were significantly better than those in control group (P< 0.05). After treatment, the expression of NO and ET of intervention group was (39.30±3.10) ng/L and (28.14±3.10) μmol/L respectively better than those of control group with significant differences (t=3.277, 2.716; P< 0.05). Conclusions Warming needle moxibustion has a remarkable clinical effect on lower limbs arteriosclerosis obliterans of blood stasis type. It is worth to be generalized.

Objective:The purpose of this study was to investigate the clinical value of CT-guided localization of pulmonary nodules with soft wire hook-wire by trailing technique.Methods:The clinical data of 211 pulmonary nodules of 185 patients from November 2020 to March 2022 in Beijing Aerospace General Hospital were retrospectively analyzed. The pulmonary nodules were localized with soft wire hook-wire by trailing technique before video-assisted thoracic surgery (VATS). The success rate, complications, pathological results and localization operations related data were statistically analyzed.Results:The success rate of localization was 97.63% (206/211), and the success rate of VATS removal was 99.53% (210/211). The average operation time was (7.19 ± 2.62) min, and the average time required for resection of lesions was 27 min (10 to 126 min). During the surgery, the soft wire hook-wire of two patient was found to be dislocated and retracted into the chest wall. The pulmonary nodules were successfully located and removed according traces left by puncture points on the lung surface. It was found that the hook-wire was located in the interlobar fissure in 3 patients. The pulmonary nodules were successfully removed by the hook-wire position and appropriately expanding the resection range. A minor pneumothorax occurred in 49 patients, but no closed drainage was needed; 12 patients developed intrapulmonary hematoma; 15 patients with chest pain were treated with analgesia.Conclusions:For small pulmonary nodules requiring thoracoscopic surgery, the computed tomography-guided pulmonary nodule localization with soft wire hook-wire by trailing technique is more convenient, safe and effective, and is worthy of promotion to use.

Conservation of Natural Resources ; Hypocreales ; isolation & purification ; Medicine, Chinese Traditional ; Natural Resources ; Species Specificity ; Tibet

Venous thromboembolism (VTE) is a preventable perioperative complication of malignant tumor in thoracic surgery. At present, low molecular weight heparin anticoagulants are the first choices for perioperative drug prevention of malignant tumors, and direct oral anticoagulants are not recommended for perioperative use of malignant tumors in thoracic surgery, but their application in other related fields is relatively mature. This article will introduce direct oral anticoagulants and analyze the prospect of their perioperative application in patients with thoracic malignant tumors. It is helpful to better understand the relevant contents of "perioperative VTE prophylaxis in thoracic cancer patients: Chinese experts consensus (2018 edition)".