Objective:　To explore the therapeutic effect and safety of thrombolysis and pure anticoagulation therapy in patients with acute submassive pulmonary embolism. Methods: A total of 63 patients with acute submassive pulmonary embolism were randomly divided into thrombolysis group (n=32) and pure anticoagulation group (n=31). Arterial blood gas index and right heart functional index changes of two groups were observed before treatment and after two-week treatment, and their therapeutic effects were compared and analyzed. Incidence of bleeding and thrombocytopenia were counted in two groups. Results: Compared with before treatment, there were significant improvements in arterial blood gas and right heart functional indexes after treatment in two groups, P<0.05 or <0.01; compared with pure anticoagulation group, there were significant rise in partial pressure of oxygen in artery [PaO2,（77.8±7.3）mmHg vs. (83.4±8.7) mmHg], right ventricular anterior wall motion [RVAWM, (4.9±1.7) mm vs. (5.8±2.2) mm]; and significant descent in alveolar-arterial oxygen difference [P (A-a)O2, (23.1±2.8) mmHg vs. (16.5±2.4) mmHg mmHg], pulmonary artery systolic pressure [PASP, (54.6±7.9) mmHg vs. (34.2±7.5) mmHg] in thrombolysis group, P<0.05 or <0.01. Total effective rate of thrombolysis group (100%) was significantly higher than that of pure anticoagulation group (80.6%), P=0.002. There were no significant difference in incidence rates of bleeding and thrombocytopenia between two groups, P>0.05. Conclusion:　Thrombolysis therapy can significantly lower pulmonary artery pressure and improve oxygenation and right ventricular function indexes in patients with acute submassive pulmonary embolism. It may be a preferred recommendation for patients without contraindications.

The communication between the students and the teacher was introduced from three aspects of foregone course, communication channel as well as homework and experiment. The individualized teaching mode was described involving expounding common difficulty, assigning and reading over the homework, individualized tutoring after school, on-line responding to the student's question, prompting the student to complete programming and answering questions in evening classes. It's pointed out that the individualized teaching has to take both common knowledge and student difference into considerations. Individulized mode enhances the teaching efficacy greatly.

Objective To study the image processing methods of electrical impedance tomography(EIT) in order to improve the display quality.Methods Evaluate the conductivity of the nodes using the conductivity of the adjacent triangle elements.The conductivity of any point in one triangle element was calculated according to the conductivity of 3 vertexes of the element by 2D linear interpolation method.Results The original blocky images of electrical impedance tomography by the triangle elements can be transformed into smoothing images.Conclusion The visual quality of the images is improved greatly.The image processing method is adaptive to all kinds of images of electrical impedance tomography based on triangle element.

Objective To evaluate the therapeutic effect of combination of sandostatin and growth hormone (GH) in the treatment of severe acute pancreatitis (SAP ). Methods Sixty patients with SAP were divided randomly into 3 groups:(1)Sandostatin treatment(ST) group (n=15);(2)combination of sandostatin with GH treatment(CT) group (n=30) ;(3)control group (n=15). The changes in serum IL-1, IL-6,TNF-? and albumin levels after treatment, and the incidence of complications, the duration of hospital stay and cost were compared among the 3 groups. Results The complications, mortality, duration of hospital stay in the CT group were significantly shorter than those in ST group and control group (all P

Objective To investigate the risk factors leading to complications in patients undergoing laparoscopic cholecystectomy (LC). Methods Clinical data of 11?974 patients undergoing LC from Mar. 1991 to June 2003 were collected and analyzed retrospectively. Fifteen clinical factors were recruited for the study in relation to surgical complications. Data were analyzed by ?2 test and Logistic regression. Results The overall operative complication rate was 1.896%. The procedure was shifted to open surgery in 2.389% of all cases, Logistic regression analysis revealed that Calot triangle adhesion, stage, expertise of the team, gallbladder wall thickness, gallbladder and vicinity adhesion were important risk factors for complications. Conclusion LC complications can be prevented by good training, strictly following protocol, and timely shifting to open surgery.

ObjectiveTo investigate the features of normal and psoriasis skin on ultrasound biomicroscopy (UBM) and explore the method of thickness measurement.MethodsUsing 50 MHz ultrasound probe of biological microscope, ultrasonographic observation and ultrasonic thickness measurement were conducted in 90 normal adults and 40 psoriasis patients. Innormal patients, ultrasound evaluations were performed at 10 different parts of the body skin.ResultsOn sonogram, the normal skin showed a “sandwich” structure with two parallel hyperechoic bands and the middle isoechoic dots and short liens. The sonograms of the psoriasis skin showed obviously thickened epidermis and dermis, disordered internal structure and clear boundary from adjacent normal skin. The range of the epidermis’ thickness measurement was between the medial forearm (0.12±0.03) mm and the palm (0.29±0.15) mm. The range of dermal thickness measurement was between the back hand (1.18±0.32) mm and parasternal (1.55±0.21) mm. Psoriasis skin was thicker than the uninvolved skin (P<0.001). And the dermis’ thickness of uninvolved skin in psoriasis patients was thicker than that of the normal adults (P<0.001).ConclusionNormal adult’s epidermis, dermis and skin appendages can be shown clearly using 50 MHz ultrasound biomicroscopy. And ultrasound biomicroscopy canaccurately measure the thickness of dermis and epidermis, which provides the basis for the diagnosis and treatment of psoriasis.

The human skull impedance was quantitatively measured by means of Frequency Response Analyzer and its software. The impedance-frequency response curves of human skull were obtained. By analyzing the curves, we found that the characteristic frequency of human skull should be around 10 KHz.
Adult ; Electric Impedance ; Humans ; Middle Aged ; Skull ; physiology ; Time Factors

The contour line of human brain was simulated by the curve-fitting methods and then the inner area was discretized by advancing-front methods which was improved at last. The curve-fitting result was similar to the CT picture of the human brain and the discrete result of inner area could be completed quickly by improved advanced-front methods. A finite element model with the contour line of human brain was built primarily which will contribute to the next algorithm study of electrical impedance tomography in human brain.
Algorithms ; Brain ; anatomy & histology ; Finite Element Analysis ; Humans ; Models, Anatomic ; Models, Neurological

The complex impedance measurements of human brain tissue in vitro are made by using four-electrode measurement methods in the frequency range from 0.1 Hz to 1 MHz. The Solartron 1255 B frequency response analyzer is used. The frequency response curves of the imaginary part of human brain's complex impedance do not appear as a single peak curve which other bio-tissues show, and the Cole-Cole diagram of human brain is different from the others as well. The construction of the equivalent circuit model obtained is more complex. However, these characteristics of human brain are all the same as rabbit brain's. The equivalent circuit model obtained will be helpful to constructing the equivalent circuit model of human head in the EIT researches.
Adult ; Brain ; physiology ; Electric Impedance ; Electrodes ; Humans ; In Vitro Techniques ; Male ; Models, Biological

It is the intent of this paper to develop better reconstruction algorithm for electrical impedance tomography (EIT). Simulation study of the reconstruction algorithm based on the sensitivity theorem is made and the reconstruction algorithm is compared with other normal algorithms. The results indicate that sensitivity method as a kind of static reconstruction algorithm has higher accuracy and speed of iteration, so it is worth researching for laboratory modality work.
Algorithms ; Computer Simulation ; Electric Impedance ; Tomography ; methods