1.Risk factors for intrapartum fever during labor analgesia and development of a prediction model
Min XU ; Jing GAO ; Huilan ZHAO ; Meixia WANG ; Ruifen JIAO ; Xueqin LIU ; Xiao CHEN ; Guohua ZHANG
Chinese Journal of Anesthesiology 2023;43(12):1454-1458
Objective:To identify the risk factors for intrapartum fever during labor analgesia and establish the prediction model.Methods:The medical records from pregnant women with intrapartum fever during labor analgesia were retrospectively analyzed. According to whether the highest body temperature ≥38 ℃, the parturients were divided into intrapartum fever group and non-fever group. The general data from patients, duration of hospital stay before labor, induced labor, prenatal hemoglobin concentration, body msaa index (BMI) during pregnancy, artificial rupture of membranes in the incubation period, frequency of vaginal examination and etc. were collected. The risk factors of which P values were less than 0.05 would enter the logistic regression analysis to stratify intrapartum fever-related risk factors, and the weighted score regression prediction model was established. Hosmer-Lemshow Test was used to assess the fit of the model, and the receiver operating characteristic curve was drawn to evaluate the model. The nomogram was drawn for visually presenting the regression model. The clinical calibration curve, decision curve analysis and clinical impact curve were drawn to assess the created prediction model. Results:There were 99 parturients developed fever during labor analgesia, with an incidence of 34.7%. The results of logistic regression analysis showed that duration of hospital stay before labor, prenatal hemoglobin concentrations, BMI during pregnancy, induced labor, artificial rupture of membranes in the incubation period and frequency of vaginal examination were the independent risk factors for intrapartum fever during labor analgesia. The area under the receiver operating characteristic curve was 0.943, 95% confidence interval was 0.916-0.969, the sensitivity was 86.9%, the specificity was 88.6%, and the Youden index was 0.755. The prediction model of the line chart was assessed by Hosmer-Lemshow, P=0.898. Conclusions:Duration of hospital stay before labor, hemoglobin concentrations, BMI during pregnancy, induced labor, artificial rupture of membranes in the incubation period and frequency of vaginal examination are independent risk factors for intrapartum fever during labor analgesia in parturients, and the risk prediction model developed can effectively predict the occurrence of intrapartum fever during labor analgesia.
2.Research on intake management in primipara labor analgesia during childbirth
Min XU ; Jing GAO ; Huilan ZHAO ; Meixia WANG ; Ruifen JIAO ; Xueqin LIU ; Xiao CHEN
Journal of Clinical Medicine in Practice 2024;28(4):79-83
Objective To investigate the effect of dietary intake on the childbirth outcomes of pri-mipara women with full-term labor analgesia.Methods A total of 400 primipara women with full-term labor analgesia were randomly divided into observation group and control group.The observation group received intake management and individualized dietary guidance,while the control group ate and drank according to their own wishes.The childbirth quality,the incidence of vomiting,the use of oxytocin due to uterine atony,the rate of intrapartum fever,the rate of perineal incision,the rate of cesarean section,the rate of vaginal assisted delivery,and the rate of postpartum hemorrhage were compared be-tween the two groups.The duration of the first stage of labor,the duration of the second stage of labor,the duration of labor analgesia,and the amount of postpartum hemorrhage within 2 hours were also compared.Neonatal Apgar score,random blood glucose,umbilical artery blood pH value,umbilical ar-tery blood lactic acid(Lac)value,the incidence of neonatal asphyxia,the incidence of neonatal fever,and the incidence of neonatal hypoglycemia were compared between the two groups.Results The ob-servation group had lower incidences of vomiting,oxytocin use rate due to uterine atony,intrapartum fever rate,perineal incision rate,transferring cesarean section rate,and vaginal assisted delivery com-pared to the control group(P<0.05).The observation group had lower rates of postpartum hemor-rhage,shorter duration of the first and second stages of labor,shorter duration of labor analgesia,and less postpartum hemorrhage within 2 hours compared to the control group,and the incidences of neonatal hyperglycemia and hypoglycemia in the observation group were lower than those in the control group(P<0.05).There were no statistically significant differences in umbilical artery blood pH value,Lac value,neonatal Apgar score,random blood glucose,neonatal asphyxia rate,and neo-natal fever rate between the two groups(P>0.05).Conclusion Intake management and individ-ualized dietary guidance during labor can reduce the incidence of uterine atony,shorten the duration of labor,decrease the incidence of dystocia,reduce postpartum hemorrhage within 2 hours and de-crease the incidence of neonatal glucose abnormality.
3.Research on intake management in primipara labor analgesia during childbirth
Min XU ; Jing GAO ; Huilan ZHAO ; Meixia WANG ; Ruifen JIAO ; Xueqin LIU ; Xiao CHEN
Journal of Clinical Medicine in Practice 2024;28(4):79-83
Objective To investigate the effect of dietary intake on the childbirth outcomes of pri-mipara women with full-term labor analgesia.Methods A total of 400 primipara women with full-term labor analgesia were randomly divided into observation group and control group.The observation group received intake management and individualized dietary guidance,while the control group ate and drank according to their own wishes.The childbirth quality,the incidence of vomiting,the use of oxytocin due to uterine atony,the rate of intrapartum fever,the rate of perineal incision,the rate of cesarean section,the rate of vaginal assisted delivery,and the rate of postpartum hemorrhage were compared be-tween the two groups.The duration of the first stage of labor,the duration of the second stage of labor,the duration of labor analgesia,and the amount of postpartum hemorrhage within 2 hours were also compared.Neonatal Apgar score,random blood glucose,umbilical artery blood pH value,umbilical ar-tery blood lactic acid(Lac)value,the incidence of neonatal asphyxia,the incidence of neonatal fever,and the incidence of neonatal hypoglycemia were compared between the two groups.Results The ob-servation group had lower incidences of vomiting,oxytocin use rate due to uterine atony,intrapartum fever rate,perineal incision rate,transferring cesarean section rate,and vaginal assisted delivery com-pared to the control group(P<0.05).The observation group had lower rates of postpartum hemor-rhage,shorter duration of the first and second stages of labor,shorter duration of labor analgesia,and less postpartum hemorrhage within 2 hours compared to the control group,and the incidences of neonatal hyperglycemia and hypoglycemia in the observation group were lower than those in the control group(P<0.05).There were no statistically significant differences in umbilical artery blood pH value,Lac value,neonatal Apgar score,random blood glucose,neonatal asphyxia rate,and neo-natal fever rate between the two groups(P>0.05).Conclusion Intake management and individ-ualized dietary guidance during labor can reduce the incidence of uterine atony,shorten the duration of labor,decrease the incidence of dystocia,reduce postpartum hemorrhage within 2 hours and de-crease the incidence of neonatal glucose abnormality.