2.Clinical analysis of using temporal base transtentorial approach to resect tumors in petroclival region
Haibo YI ; Rui FENG ; Ruisheng LIN ; Jingfu WANG ; Tao YU
Chinese Journal of Postgraduates of Medicine 2013;36(26):27-30
Objective To discuss the surgical method of resection of petroclival tumors used temporal base transtentorial approach.Methods Analyzed 26 cases of petroclival tumors.All of them were surgically treated under intraoperative neurophysiological monitoring by temporal base transtentorial approach.Firstly the supratentorial part of tumors were resected by pieces,and then the tentorium was cut open,in order to resect residue of the subtentorial part of tumors.This surgical maneuver was applied to reduce the retraction to surrounding vessels,nerves and brain stem,as well to protect important structures and to finally achieve radical removal of the tumors.The efficacy and complications were observed.Results Among 26 cases,19 cases (73.1%,19/26) achieved total removal,5 cases (19.2 %,5/26) achieved subtotal removal and 2 cases (7.7%,2/26) achieved great partial removal.There was no surgery-related death.Eleven cases suffered from partial neurological deficit.All cases were followed up for 3 months to 4 years,3 cases underwent complete recovery,4 cases underwent partial recovery,and 4 cases underwent permanent deficit.Conclusions Using temporal base transtentorial approach to resect petroclival tumors is convenient,applicable,safe and with minimal injury and with high proportionality of total resection.Under intraoperative neurophysiological monitoring,this approach may be an ideal choice for surgical treatment of these tumors.
3.Advances in study of anticancer properties of Allii Macrostemonis Bulbus.
Quan-kui LAI ; Rui-lin TAO ; Yu-jia ZHAO ; Rui-fei ZI ; Quan HE
China Journal of Chinese Materia Medica 2015;40(24):4811-4816
A commonly used Chinese crude drug Allii Macrostemonis Bulbus has been shown to possess good anticancer activities and related properties such as antioxidation, nitrite scavenging, nitrosamine synthesis blocking and immune enhancement, and has been widely used as an effective auxiliary drug in the treatment of some malignant tumors. This paper systematically reviews the advances in the study of anticancer-related activities of Allii Macrostemonis Bulbus's various components such as raw juice, extracts, saponins, volatile oil, polysaccharides, nitrogen compounds, etc.
Allium
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chemistry
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Animals
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Antineoplastic Agents, Phytogenic
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pharmacology
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Antioxidants
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pharmacology
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Humans
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Oils, Volatile
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pharmacology
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Plant Extracts
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pharmacology
4.Attempt to use heuristic teaching to cultivate students' ideation
Yu-xia LIU ; Rui-ling CHEN ; Feng-e SUN ; Feng-lin ZHU ; Chun-tao YU ; Rui-lan NG ZHA
Chinese Journal of Medical Education Research 2011;10(8):1007-1008
Heuristic teaching is propitious to cultivating students' ideation. We have used different heuristic modes for example problems, stories, contrast, associationin and so on to cultivate medical students' ideation in pathobiology and immunology teaching and acquired good effect.
5.Effect of Rehabilitation Medical Professional Training in Guangzhou, China
Zhou XING ; Zhitong LIN ; Cuihuan PAN ; Yan CHEN ; Rui YU ; Yu ZHOU ; Zhengmao YE ; Zhen FU
Chinese Journal of Rehabilitation Theory and Practice 2015;21(3):370-372
Objective To investigate the effect of rehabilitation professional training. Methods Based on the 10 tertiary hospitals in Guangzhou, Guangdong, the professionals from communitiy hospitals were trained. The scores of knowledge and practice tests were analyzed in 2 terms of training. Results The students performed better in the practice test (82.01±8.91) than knowledge (71.08±10.05) (P<0.01). The score of knowledge tests was better in the second term than the first (P<0.05), no difference between them in the score of practice test. Conclusion Rehabilitation professional training in Guangzhou can improve the ability of service of medical rehabilitation.
6.Recombinant human interferon alpha 2b broad-spectrum anti-respiratory viruses pharmacodynamics study in vitro.
Hui-Qiang WANG ; Lin-Lin MA ; Jian-Dong JIANG ; Rui PANG ; Yu-Jun CHEN ; Yu-Huan LI
Acta Pharmaceutica Sinica 2014;49(11):1547-1553
This study is to investigate the effect of recombinant human interferon alpha 2b against broad-spectrum respiratory viruses in vitro. At the cellular level, the effect of the recombinant human interferon alpha 2b on influenza A virus was detected using real-time fluorescence quantitative RT-PCR. The effects of the recombinant human interferon alpha 2b on influenza B virus, parainfluenza virus, respiratory syncytial virus (RSV) and coronavirus were detected using cytopathic effect (CPE) method. In this study, the therapeutic index of recombinant human interferon alpha 2b anti-HPIV was 1476.63, the therapeutic index of recombinant human interferon alpha 2b anti-RSV was 141.37, the therapeutic index of recombinant human interferon alpha 2b anti-coronavirus was more than 2820.76, and the antiviral effect of recombinant human interferon alpha 2b was better than ribavirin (RBV). Recombinant human interferon alpha 2b has a stronger inhibitory effect on different influenza A virus RNA than drug control. The therapeutic index of recombinant human interferon alpha 2b anti-influenza B virus was 2.74, with modest effect. Recombinant human interferon alpha 2b in vitro has broad spectrum antiviral activities, low toxicity and high therapeutic index. Recombinant human interferon alpha 2b is expected to become the efficient medicine in clinical against respiratory viruses, as well as provide better services for prevention and treatment of respiratory viruses' infections.
Antiviral Agents
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pharmacology
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Humans
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Influenza A virus
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drug effects
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Influenza B virus
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drug effects
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Interferon-alpha
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pharmacology
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Parainfluenza Virus 1, Human
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drug effects
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Recombinant Proteins
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pharmacology
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Ribavirin
8.Study on human bone marrow mesenchymal stem cells marked by enhanced green-fluorescent protein gene.
Xu HE ; Yu-lin LI ; Xin-rui WANG ; Yun NIU ; Hai-ying ZHANG
Chinese Journal of Pathology 2009;38(2):123-124
Bone Marrow Cells
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cytology
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Cell Cycle
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Cell Differentiation
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Cell Nucleus
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genetics
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Cells, Cultured
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Diploidy
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Genetic Vectors
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Green Fluorescent Proteins
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genetics
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metabolism
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Humans
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Immunophenotyping
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Mesenchymal Stromal Cells
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cytology
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metabolism
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ultrastructure
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Transfection
10.Professor Sun Shen-tian's experience in treatment of mental diseases.
Chinese Acupuncture & Moxibustion 2009;29(8):639-641
Professor SUN Shen-tian is an expert in acupuncture and moxibustion science of TCM and neurology, especially in the treatment of neurology difficult diseases by using the therapy of acupuncture and moxibustion and combination of TCM with western medicine, showing his ingenuity and obvious therapeutic effect. In treating mental diseases, professor SUN considers that the morbidity of mental diseases is mainly related to the malfunction of brain, therefore regulating mind is the key to treat this kind of disease, Baihui (GV 20), Yintang (EX-HN 3), emotional area and Zone 1 of SUN's abdominal acupoints are often selected. This present article introduces the principle of treatment based on syndrome differentiation and routine selecting acupoints, attached with four effective cases in treating mental diseases by professor SUN applying "the methods of regulating vitality and increasing intelligence".
Acupuncture Points
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Acupuncture Therapy
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Adult
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Aged
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China
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History, 20th Century
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History, 21st Century
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Humans
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Male
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Medicine, Chinese Traditional
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Mental Disorders
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therapy
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Middle Aged