OBJECTIVETo evaluate the efficacy of tadalafil in the treatment of ED after transurethral resection of the prostate (TURP).

METHODSA total of 113 patients with ED after TURP received 3 months of tadalafil treatment and were followed up for 6 months. The IIEF-5 scores of the patients and the number of successful penile intromissions and sustained penile erections in the patients' sexual life diary were compared before and after the treatment.

RESULTSThe IIEF-5 scores were 9.83 +/- 3.96 before the medication, 20.23 +/- 3.25 after it, and 17.28 +/- 3.03 at 6 months after drug withdrawal, with statistically significant differences between pre- and post-treatment (P < 0.05). The patients' success rates of penile intromission and sexual intercourse were increased from 44.8% and 7.5% before the medication to 81.7% and 63.2% after it.

CONCLUSIONTadalafil can be used as a first-line drug for the treatment of ED after TURP.

Aged ; Carbolines ; therapeutic use ; Erectile Dysfunction ; drug therapy ; etiology ; Humans ; Male ; Middle Aged ; Phosphodiesterase Inhibitors ; therapeutic use ; Tadalafil ; Transurethral Resection of Prostate ; adverse effects ; Treatment Outcome