This article is the second one of the series articles about three kinds of ethics committee. The author will expound the background, definition, organization, function and significance respectively of the Institutional Review Board.

Atherosclerosis,as a chronic inflammatory vascular disease,involves many cellular and molecular events in its formation and progression from an early fatty streak lesion to a highly dangerous rupture-prone plaque.The vulnerability or destabilization of atherosclerotic plaques is closely associated with plaque composition.Such imaging modality as magnetic resonance imaging(MRI),which allows of the evaluation of the plaque composition at the cellular and molecular level,may differentiate vulnerable and destabilized plaques and monitor the efficacy of antiatherosclerotic therapies.This paper gives an overview of molecular imaging strategies currently used for targeting the inflammation markers of atherosclerotic plaque vulnerability.

To keep vocational schools distinctive and vigorous,top priority should be placed in teachers'training and teaching,making practice skill training systematic,embodying practical open professional principle based on vocational education in the process of practice teaching,by the teachers'guidance and stimulating students to actively participate in practice,reforming teaching ways and means.

Objective The aim of this study was to explore the effects of volume controlled ventilation (VCV),pressure controlled ventilation(PCV)and pressure controlled ventilation-volume guaranteed (PCV-VG)on respiration and circulation in elderly patients undergoing thoracic surgery. Methods Thirty-six elderly patients who underwent thoracic surgery were enrolled in our study. Patients were divided into VCV,PCV and PCV-VG groups according to randomized design. The hemodynamic and respiratory data and the arterial blood gases had been recorded in the pre-operation,20 min,40 min,60 min after OLV and 20 min after the resumption of two lung ventilation. Results Compared with VCV group,Ppeak value was significantly lower in PCV and PCV-VG groups(P < 0.05),and the difference was not found between the PCV and PCV-VG groups. PaO2 levels in PCV and PCV-VG groups were higher than that in VCV group after the point of OLV+40(P < 0.05). Comparison of PCV group,PaO2 in PCV-VG group was higher,but did not show a significantly improved during OLV(P > 0.05). Conclusion Compared with VCV,the use of PCV and PCV-VG have significant advantages in the operative oxygenation and airway pressure for elderly patients undergoing OLV.

Chimeric antigen receptor natural killer cell (CAR-NK) is a new promising immunotherapy. NK cell can derive from peripheral blood cells, cord blood cells, NK-92 cell line and iPSC cells. CAR-NK cells can recognize target antigens non-specifically and are not restricted by human leukocyte antigens. Allogeneic infusion of CAR-NK cells does not cause graft-versus-host disease. It has a strong effect on primary cells of leukemia, lymphoma and multiple myeloma, thus making animal models have strong anti-tumor effect. Therefore, as a "off-the-shelf" product, CAR-NK cells have a wide range of clinical applications. In this paper, the construction of CAR-NK vector and its preliminary clinical application in hematological tumors and the challenges were reviewed.

Objective To explore the current status of sexual education and real needs of college freshmen in Kunming.Methods By applying random sampling,350 students from three universities in Kunming were investigated by seff-administered questionnaire,and 310 valid questionnaires were recovered.Fesults 23.9％ students confirmed that the schools do not provide courses related to sexual health,and 22.9％ of the surveyed students claimed that they even did not heard any sexual education courses in their schools.The main sources of students to acquire information in terms of sexuality and sexual health are network television,video magazines,friends and classmates.Both male and female students are more acceptable to carry out sex education lectures.There were significant differences between male and female students in the form of obtaining sexual education,the content of sexual education and the demand of sexual education in three aspects (P＜0.05).Girls tend to carry out sexual education in the form of major courses,but boys tend to the form of playing video or distributing books and periodicals (P＜0.05).Girls tend to obtain the courses on sexually disease,AIDS,heterosexual intercourse,or love psychology,but boys tend to contraceptive knowledge and skilIs,or Sexual value orientation (P＜0.05).Girls are more likely to acquire the knowledge of masturbation,sexual health,or sexual health,but boys prefer to the knowledge of sexual psychology,parasexuality,or homosexuality (P＜0.05).Conclusion As a main body of educational institute for young people,all universities should provide training courses related to sexuality and sexual health at the early stage of higher education in order to equip college students with essential knowledge and skills to have safer and positive impact on their college studies.

Objective To evaluate the influence of family intervention mode in patients with schizophrenia characterized by negative symptoms.Methods A total of 120 cases of hospitalized patients with schizophrenia characterized by negative symptoms were randomly divided into the observation group and the control group with 60 cases in each group.The observation group received treatment through family intervention mode based upon routine care,while the control group used routine care.Influences were assessed with Nurses’ Observation Scale for Inpatient Evaluation (NOSIE) and the Scale for Assessment of Negative Symptoms (SANS) before treatment and at the end of 6th,12th week treatment.Results No significant difference of NOSIE score or SANS score were found upon admission between the observation group and the control group.At the end of the 6th week or the 12th week,total and all factors’ scores of the NOSIE and SANS of both groups were better compared with pretreatment,the observation group was significantly better than the control group.Conclusions Family intervention model could significantly relieve the negative symptoms of schizophrenia,improve the patients’ clinical efficacy and is an effective adjunctive therapy for schizophrenia.

Objective To gain a better knowledge of the education for masters in clinical medicine (general practice) and provide a reference for the better exploration of the training mode of GP students.Methods 9 colleges and universities enrolling students for this program were selected with stratified sampling.A questionnaire was conducted in terms of admission,curriculum setting,clinical training,guidance and evaluation through officials in charge of graduate affairs from February to July in 2014.Descriptive analysis was performed to the investigation results,using SPSS 20.0 statistical software.Results A full-time undergraduate degree in clinical medicine was explicitly required in 88.9％ (8/9) of colleges and universities.The average total credits of the course were 23.7 and the average clinical training duration was 32.4 months.Tutor group was adopted in all colleges and universities.The assessment and evaluation of the GP masters was mainly composed of multiple forms of process assessment and final evaluation.Conclusion We suggest attaching more importance to the improvements of enrollment policy,curriculum system,clinical training,standardized training base construction,teaching staff,and evaluation system in order to explore GP training mode in accord with the law of general practice and suitable for China's national conditions.

Objective To develop a mental maturity test for adults.Methods On the basic of correlative theories,the structure of Adults Mental Maturity was established by using interview and exploratory factors analysis. The reliability and validity of this test were examined. Results Through exploratory factor analysis the test was of six factors self-insight, social cognition, emotion management, social contact style, adapting ability, loving ability. The reliability of test was 0.621～0.853, and the retest reliability was 0.431～0.831. Conclusion The test of mental maturity for adults is of better reliability and validity, and can be used in practice.

Objective To study a new method of correcting flaring ear. Methods Auricular cartilage was slited from posterior auricula. On Gibson's principle of cartilage distortion antero-lateral cartilage membrane was scarified in order of the involute interpolation of anthelix and cartilage membrance was ground. Then the cartilage outside the slited line was put behind the cartilage inside the slited line. Finally,cartilage was operated with Mustarde's mattres suture. Results 12 patients with flaring ear ( 14 ears) were corrected with this operating method and appearance of corrected ears were very good after operation. Following up for 6-18 months, no one recurred. Conclusion Otoplasty of slited cartilage is an effective method of correcting flaring ear.