OBJECTIVE To evaluate the risk factors for postoperative nosocomial infection(NI) among inpatients with cervical carcinoma.METHODS A prospective and retrospective study was carried out to investigate the clinical data of patients with cervical carcinoma in department of gynecology during the period from Jan 1 to Dec 31,2003.RESULTS The incidence and case incidence of NI were 22.88% and 23.99%,urinary tract infection((52.3%)) was the most common infection,followed by vaginal margin infection and pelvic infection.NI was closely related with diabetes mellitus,the duration of catheter reservation,and different operators.CONCLUSIONS NI is high in postoperative patients with cervical carcinoma,which should be paid attention during the course of clinical treatment.

OBJECTIVE To explore the risk factors of infection in patients with chemotherapy-induced neutropenia in order to offer scientific references for clinical treatment.METHODS With case-control study,two hundred and fifty-six cancer patients with chemotherapy-induced neutropenia were compared between the infection group and non-infection group.The data were analyzed on risk factors by univariate analysis(Chi-square test) and multivariate analysis(non-conditional Logistic regression models).RESULTS Multivariate analysis showed that early lymphopenia after chemotherapy(OR=3.347),the depth of the Absolute neutrophil count nadir(

Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) is a novel coronavirus which can cause severe acute respiratory illness with a high mortality rate .There is no proven medication or vaccine for MERS-CoV .Currently MERS-CoV has spread from the main epidemic area ,the Middle East area ,to many other countries including United States of America and has the potential of global endemic .It has raised global public health concerns regarding the current situation and its future evolution .This review will mainly focus on the research progress of MERS-CoV about the animal reservoir and transmission , infection mechanisms and development of anti-viral drugs or vaccine .The goal is to provide with useful references to the devel-opment of specific drug and vaccine and an effective control and prevention of M ERS-CoV infection .

Objective To study the correlation of serum adiponectin (ANP) and brain natriuretic peptide (BNP) levels with left ventricular hypertrophy in essential hypertension patients,and to investigate its potential mechanism.Methods 80 patients with essential hypertension in our hospital were recruited.Secondary hypertension,cardiac,brain and renal insufficiency and diabetes mellitus were excluded in the study patients.Patients were divided into 2 groups:left ventricular hypertrophy group (LVH group,n=40) and hypertension group (hypertension patients without left ventricular hypertrophy,n=40).Age-,sex-,body mass matched health subjects were selected as control group (n =40).Serum levels of ANP and BNP were determined by enzyme-linked immunosorbent assay (ELISA).Left ventricular end diastolic dimension (LVEDD),left ventricular posterior wall thickness (LVPWT) and interventricular septum thickness (IVST) were detected by ultrasonic cardiography.Left ventricular mass (LVM) and left ventricular mass index (LVMI) were calculated according to formula of Devereux.Results There were significant differences in serum levels of APN and BNP and LVMI between hypertension,LVH and control groups [(7.9±0.3) mg/L,(6.7±0.1)mg/L vs.(12.0±0.2)mg/L,(116.1±16.1)μg/Lvs.(182.4±18.5)μg/L,(104.0± ±9.6)g/m2,(153.7±21.0)g/m2 vs.(83.1±9.1)g/m2,respectively,all P＜0.01].Serum APN level was negatively correlated with the severity of LVH (r=-0.789,P＜0.01),while serum BNP level was positively correlated with the severity of LVH (r=0.811,P＜ 0.05).Conclusions Serum APN and BNP levels have correlation with hypertension and hypertension related LVH.

To explore the effect of the intervention of clinical pharmacists on the rational use of potassium magnesium aspartate . Methods:The prescriptions of outpatients in the fourth quarter of 2013 and those of emergency in the second quarter of 2014 with potassium magnesium aspartate injection were collected and analyzed. The unreasonable use rate of the drug before and after the intervention was compared. Results:The unreasonable use rate of potassium magnesium aspartate before the intervention was 35. 4%, that after the intervention was 15. 8%, and the difference was statistically significant(P<0. 01) . The difference in beyond the indica-tion, high concentration and unreasonable compatibility of the drug before and after the intervention was statistically significant ( P<0. 01 or P<0. 05) . Conclusion: The intervention of clinical pharmacists in the use of potassium magnesium aspartate is effective, which should be performed continuously.

Objective To explore the clinical effect of laparoscopic operation in the treatment of children with incarcerated oblique inguinal hernia.Methods 60 cases of children with incarcerated oblique inguinal hernia in our hospital from February 2012 to June 2014 were retrospectively analyzed.30 children undergoing laparoscopic op-eration were set as the observation group and 30 other patients undergoing traditional emergency operation as the con-trol group.The two groups were compared in terms the operation time, incision length, postoperative complications, hospitalization expenses and other data.Results The average operation time, bleeding quantity, length of incision, and hospitalization expenses in the observation group were lower than those of the control group.6 months of follow-up showed no recurrence in the two groups.Conclusion Laparoscopic operation in the treatment of children with in-carcerated oblique inguinal hernia is characterized by fast surgery, minimal incision, less complications, accurate de-termination of the incarcerated tissue activity, visibility of the side occult hernia and lower recurrence rate.Therefore, it is worthy of promotion and application.

Objective:To investigate the morphology and growth kinetics of the cells derived from the adult normal and herniated nucleus pulposus tissues.Methods: The cells derived from the adult normal and herniated nucleus pulposus were cultured in vitro.Passage 1,3,5 cells were chosen for light microscope and electron microscope observation.The cell growth rate,MTT value,maximal growth density,cellular mitotic index,cloning efficiency,and other parameters were observed in normal and herniated nucleus pulposus and the results were compared.Results: Compared with adult normal nucleus pulposus cells,the cells isolated from herniated nucleus pulposus were irregularly arranged and lost polarization,with rough endoplasmic reticulum slightly dilated.Under the same cellular density and culture conditions,the growth rate of passage 1 cells from adult normal and herinated nucleus pulposus had no significant difference,but the differences of passage 3 cells(P(0.05);) those of passage 3 cells were respectively 6.96?0.19 and 5.48?0.22,0.154?0.018 and 0.110?0.009,(22.52?(2.16)‰) and((16.68?)(2.35)‰,) and(48.7?3.3)% and(40.7?2.5)%;and of passage 5 cells were respectively 2.42?0.13 and 0.98?(0.14,) 0.085?0.006 and 0.050?0.007,(15.61?1.96)‰ and(9.34?2.12)‰,and(40.2?2.3)% and(28.34?(2.9)%.) There were significant differences between the parameters of passage 3 and 5 cells(P

Objective To develop ECG Holter system with SD card as storage medium. Methods Data that used MSP430F449 SCM to acquire 3-channel ECG signal to record SD card through serial peripheral interface were reviewed and analyzed on computer. Results Portable ECG Holter System based on SD card is realized. The using of SD card can enhance storage performance. Conclusion Low-cost, and high-performance solution program is observed.

OBJECTIVETo observe the efficacy difference on the motor function in the children of cerebral palsy between acupuncture combined with acupoint embedding therapy and simple acupuncture.

METHODSOne hundred and twenty children of cerebral palsy were randomized into an observation group and a control group, 60 cases in, each one. In the observation group, acupuncture was applied in combination with acupoint embedding therapy. For the acupoint embedding therapy, the main acupoints were Pishu (BL 20), Shenshu (BL 23); the supplementary points were Dazhui (GV 14), Mingmen (GV 4), Yaoyangguan (GV 3), Sanjiaoshu (BL 22), Xinshu (BL 15) and Ganshu (BL 18). The catgut was embedded to the acupoints. Acupuncture was applied to the acupoints on the head and four limbs and the needles were retained for 40 min after qi arrival. In the control group, the simple acupuncture was applied, except for the acupoint embedding therapy. The rest treatment was the same as the observation group. The treatment lasted continuously for 3 months in the two groups. Before and after treatment, the gross motor function measure (GMFM) and the gross motor function classification system (GMFCS) were used for the assessment and the efficacy was analyzed.

RESULTS(1) After treatment, the total score of GMFM was increased in the two groups (both P<0. 01) and the score in the observation group was higher than that in the control group (P<0. 05). (2) The scores in A and B areas of GMFM were all improved in the two groups after treat ment (all P<0. 01) and the scores in the observation group were higher than those in the control group (P<0. 01 P<0. 05). (3) The total effective rate was 76. 7% (46/60) in the observation group, which was better than 55. 0% (33/60) in the control group (P<0. 01).

CONCLUSIONThe combined therapy of acupuncture and acupoint embedding much better improves the motor function in the children of cerebral palsy as compared with the simple acupuncture.

Acupuncture Points ; Acupuncture Therapy ; Catgut ; utilization ; Cerebral Palsy ; physiopathology ; therapy ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Motor Activity

Objective To investigate the therapeutic effect of loosening manipulation on neck tenderness points for cervicogenic tinnitus . Methods Forty cervicogenic tinnitus patients were treated with loosening manipulation on neck tenderness points. Tinnitus grading was carried out before and after treatment by following Tinnitus Severity Grading Criteria for the evaluation of therapeutic effect. Results ( 1) Tinnitus was relieved after treatment for one week and 2 weeks, and at the end of treatment course (P<0.05 compared with that before treatment). (2) After treatment for 3 continuous weeks, the cure rate was 25.0% ( 10/40) , the markedly effective rate was 37.5% ( 15/40) , the effective rate was 27.5% ( 11/40) , the ineffective rate was 10.0% ( 4/40) , and the total effective rate was 90.0%. Conclusion Loosening manipulation on neck tenderness points is effective on relieving cervicogenic tinnitus.