Adult ; Benzene ; adverse effects ; Hearing ; drug effects ; Humans ; Noise, Occupational ; adverse effects ; Occupational Exposure ; adverse effects

S100A,a Ca2+-depending inotropic factor in the heart,is found decreased during hear failure. Increase of S100A1 protein expression can improve cardiac function by regulating Ca2+ transportation, inhibiting left ventricular remodeling, decreasing apoptosis,and restoring energy supply of failing heart. Therefore,recovery of S100A1 protein expression in the failing heart is an effective strategy for treatment of heart failure.

OBJECTIVE To introduce the methods of hospital disease prevention and control and advance the level of infection management.METHODS We constituted and administered thoroughly hospital regulations of infection prevention and control according to our country and PLA′s laws and statutes.RESULTS To eliminate effectively the outbreak and epidemic of the hospital infection and cross infection,and complete the work of hospital disease prevention and control that leads appointed us.CONCLUSIONS Disease prevention and control are the key to the infection control in hospitals.

Objective To patients with neonatal dacryocystitis underwent left Ofloxacin Gel, Tobramycin and Dexamethasone Ophthalmic Ointment and lacrimal surgery combined with treatment effects were observed.MethodsIn Ningxia Hui Autonomous Region Qingtongxia City People's Hospital during December 2015 to December 2016 for dacryocystitis in 130 cases according to the data analysis, using different treatment schemes were divided into two groups, 65 cases underwent lacrimal surgery as control group, 65 cases and left Ofloxacin Gel, Tobramycin and Dexamethasone Ophthalmic Ointment combined treatment as the observation group, blocking characters and comparison of complications two groups of clinical curative effect, lacrimal duct.ResultsIn the observation group, the total effective probability of 96.92% higher than the control group of 80.00%(P<0.05), and the nasal deformity, nasolacrimal duct, lacrimal bone deformity multiple adhesions or obstruction and lower incidence of membranous obstruction of lacrimal duct is lower than that of control group (P<0.05);the total complication rate in the observation group(3.08%) than the control group(21.54%)low (P<0.05).ConclusionNeonatal dacryocystitis underwent left Ofloxacin Gel, Tobramycin and Dexamethasone Ophthalmic Ointment and lacrimal surgery combined therapy can improve the clinical symptoms and characteristics of lacrimal duct obstruction, and reduce postoperative complications, which may be of clinical promotion and application.

Objective To investigate the comparison of blood uric acid and bilirubin levels on patients with acute cerebral infarction and the clinical curative effect of Donhong injection.MethodsA total of 68 patients with acute cerebral infarction from our hospital neurology, according to different therapeutic methods were divided into control group and experimental group with 34 cases in each group, two groups were treated by conventional treatment, patients in the control group were treated by blood flux injection 400 mg+5% glucose injection 250 mL intravenous drip, once a day;patients in the experimental group were treated by Dan red injection 40 mL+5% glucose injection 250 mL intravenous drip, once a day,2 groups of patients were treated for 2 cycles,a cycle with 7 d.Compared the clinical efficacy, blood uric acid, bilirubin, blood homocysteine, hyperensitive C-reactive protein, serum inhibition C and adverse reactions in the two groups after treatment.ResultsCompared with the control group, the experimental group clinical total effective rate was higher after treatment (P< 0.05).Compared with the control group, the experimental group blood uric acid, blood homocysteine, hypersensitive C-reactive protein, serum inhibition C levels were lower (P< 0.05), bilirubin level was higher(P< 0.05).Adverse reactions compared between the two groups, there was no statistically significant difference.ConclusionDonhong injection in the treatment of acute cerebral infarction clinical curative effect is distinct, dacrease blood uric acid level and increase bilirubin level, improve endothelial cell damage, protect the brain tissue.

Objective To observe the adverse effects of passive smoking on antioxidant capacity and spermiogenesis of the testis and epididymides in rats.Methods SD rats were exposed to smoke in a self-made passive smoking chamber twice a day for 48 days.At the end of the experiment,the right testis and epididymides homogenate were prepared and the level of SOD,GSH-Px, NOS,NO and MDA were measured respectively.The sperms of left epididymides were observed by light microscope for determining sperm density,motility,progressive motility,fast progressive motility.The microstructure changes of left testis were observed.Results In passive smoking group,the level of MDA was significantly increased(P

Adolescent ; Adult ; Aged ; Diagnosis, Differential ; Ependymoma ; pathology ; Female ; Follow-Up Studies ; Humans ; Immunohistochemistry ; Magnetic Resonance Imaging ; Male ; Meningeal Neoplasms ; diagnostic imaging ; metabolism ; pathology ; surgery ; Meningioma ; diagnostic imaging ; metabolism ; pathology ; surgery ; Mucin-1 ; metabolism ; Oligodendroglioma ; pathology ; Tomography, X-Ray Computed ; Vimentin ; metabolism ; Young Adult

Flavonoids ; analysis ; Soybeans ; analysis

Objective To evaluate the epidemiological characteristics of brucellosis in Jinan, Shandong Province, and to analyze epidemic trend and its cause. Methods Epidemic data of human brucellosis from 2004 to 2007 in Jinan were collected from National Disease Supervision Information Management System. The rose bengal plate agglutination test(RBPT) and standard tube agglutination test(SAT) were employed to detect brucellosis in the serum samples of high-risk exposure groups involved in livestock transaction, slaughter and raising where brucellosis had been outbreak in the last three years, and epidemiological survey was conducted on the confirmed patients in 2007. Results A total of 32 brucellosis cases occurred in 2004-2007 in Jinan, among which 15 cases in 2007, 3.75 times(15/4) of those in 2004. One hundred and seventy-eight blood samples were collected from high risk population, and positive detective rate was 11.24%(20/178). Most of the patients were found in Zhangqiu and in the months from March to September, accounting for 93.33% (14/15). Farmers accounted for 93.33% (14/15) in all cases. Sixty-six point six seven percent(10/15) of the patients were over 50 years old. Male to female was 2.75: 1(11: 4) in ratio. There was a tendency of family aggregation. Two or three cases occurred in each of 3 families. All cases had a contact history with cattle and sheep, and the diagnosis were confirmed between 17-529 days(median being 70 days), in which 86.67%(13/15) of the cases were confirmed by The Centers for Disease Control and Prevention. Conclusions Brucellosis epidemic of Jinan is in an upward trend. Zhangqiu is the main epidemic region. Spring and summer are the prevailing periods, most of the patients are old male farmers were the majority of the patients. It is believed that the epidemic is primarily due to potential infection sources, incompetent quarantine of imported livestock and poor awareness of self-protection among high-risk occupational groups.

Objective To detect the serum growth hormone(GH),insulin-like growth factor-I(IGF-Ⅰ),insulin-like growth factor binging protein-3(IGFBP-3) levels in children with hypothyroidism and explore the change regulation of GH-IGF axis and thyroxine.Methods Fifty-six hypothyroidism children were divided into congonital hypothyroidism(CH)(14 cases) and Hashimoto's thyroiditis(32 cases).Serum GH,IGF-Ⅰ,IGFBP-3 levels of 56 hypothyroidism children before and after luothyroxine sodium L-T4 treatment and 50 normal children were detected with radioimmunoassay or enzyme-linked immunosorbent assay methods.Results Serum IGF-I,IGFBP-3 levels in 9 CH newborn group were lower,and they were normal after thyroxine substitute therapy.But those of 5 children with CH and 32 cases with Hashimoto's thyroiditis were not significantly changed.Conclusions The GH-IGF axis is inordinate in the CH children,which is an important reason of stature short.Early thyroxine substitute therapy is very helpful to maintain normal growth and development of children with CH.