Objective To investigate the clinical effect of Edaravone on transient ischemic attack and serum superoxide dismutase and malondialdehyde levels in the elderly.Methods Ninety eight cases with transient ischemic attack treated in our hospital were chosen as the objects, which were randomly divided into observation group and control group (n=49 for each).Patients in observation group were treated with Edaravone combined with conventional therapy, and patients in control group were treated with conventional therapy.The clinical effect and levels of SOD and MDA were analyzed and compared between the two groups.Results The effective rate and total efficiency were higher in observation group than in control group (79.6％ vs.55.1％, 95.9％ vs.83.7％, x2 =6.914 and 4.354, P=0.008 and 0.032).The SOD level was higher and the MDA level was lower in observation group than in control group (both P＜0.001) after treatment.Conclusions Edaravone could improve the symptoms of transient ischemic attack in the elderly, and increase the activity of SOD and reduce MDA level, which is helpful to reduce lipid peroxides, alleviate free radical toxicity, and improve the anti-oxidation ability.

Objective To study the correlation between serum neuron-specific enolase (NSE) and acute intracerebral hemorrhage (ICH). Methods The serum level of NSE was measured in 40 patients with acute ICH by ELISA and compared with normal control subjects. The relationship between serum NSE level and neurological deficit scores (NDS), volume and site of hemorrhage were analyzed.Results The serum level of NSE in ICH group increased within 48 hours, peaked at 3～5 d, obviously higher at 6～9 d and at 10～14 d compared with the control group (P

Objective:To explore the current situation of rehabilitation resource and the influencing factors of rehabilitation nursing needs of patients at home in Xuzhou so as to provide a reference for home rehabilitation for patients.Methods:From October 2018 to December 2018, this study investigated all rehabilitation medical institutions (rehabilitation specialized hospitals, general hospitals with Rehabilitation Department, community health service institutions) in Xuzhou City by general investigation. Rehabilitation specialized hospitals in Xuzhou were investigated with the method of field visit and questionnaire survey, and the investigation content included the situation and professional categories of rehabilitation professionals. At the same time, totals of 411 patients with the needs for rehabilitation in Xuzhou were investigated, and the investigation content included the basic situation, rehabilitation needs of patients, contract service by family doctors. This study also analyzed the influencing factors of home rehabilitation nursing needs by Logistic regression.Results:There were 120 rehabilitation medical institutions in Xuzhou City. The bed number was 2 675 accounted for 57.98% (2 675/4 314) of the bed number shall be equipped with. There were 402 rehabilitation physicians, 432 rehabilitation nurses and 808 rehabilitation therapists respectively occupied 31.07% (402/1 294) , 16.69% (432/2 588) and 31.22% (808/2 588) of the planning. There were 30.90% (127/411) of rehabilitation patients signed a contract with community doctors, and 45.67% (58/127) of them dissatisfied with community doctors service and the satisfaction rate was 18.90% (24/127) . The influencing factors of family doctor contract included the ages of patients ( OR=0.557) , history of hemiplegia ( OR=1.520) and the number of community doctors ( OR=1.131) . The young the ages were, the better the contract degrees were. The factors promoted the contract were hemiplegia and increasing in the number community doctors. Conclusions:In Xuzhou, the rehabilitation medical resource allocation cannot meet the needs of the masses. The insufficient rehabilitation medical resource allocation reflected in the lack of rehabilitation talents, rehabilitation medical institutions and rehabilitation equipment. The rate of family doctors contract service was in the low level, and there are still great difficulties in the home rehabilitation.