Objective To investigate the effect of intensive follow-up on the correction of mild anemia among infants in the community. Methods Eighty four infants aged 6-12 months with mild anemia managed systematically in the child health clinic of Changzhou Lanling Community Health Service Center were enrolled from April 2016 to January 2017. Seventy five cases completed the study, including 36 cases managed with intensive follow-up (study group) and 39 cases managed with routine procedure (control group). The hemoglobin(Hb) levels, Hb changes, the rates of correction and closure of anemia and the medication of iron treatment were compared between two groups during the 2 and 6 month-follow-up. Results The Hb value, Hb changes, the rate of correction in study group were significantly higher than those in control group after 2 monthsof treatment [(113.50 ± 5.40)g/L vs. (109.13 ± 7.91)g/L, t=2.772, P=0.007;(13.22 ± 4.56)g/L vs. (7.54 ± 6.75)g/L, t=4.240, P<0.001;77.8％(28/36) vs. 46.2％(18/39),χ2=6.617, P=0.010, respectively]. In 6 month-follow-up, the Hb value, the rate of correction and closure rate in study group were significantly higher than those in control group [(116.22±3.72)g/L vs. (112.23±5.90)g/L, t=3.471, P=0.001;88.9％(32/36) vs. 66.7％(26/39),χ2=4.082, P=0.043;77.8％(28/36) vs. 41.0％(16/39),χ2=8.967, P=0.003, respectively]. For infants receiving iron treatment, the proportion of standardized medication in study group was significantly higher than that in control group after 2 months (14/14 vs. 4/8, χ2=5.525, P=0.019); the Hb values in study group were significantly higher than those in control group after 2 months[ (109.93 ± 3.51)g/L vs. (102.88 ± 2.88)g/L, t=4.820, P<0.001)and 6 months[(114.50±4.00)g/L vs. (108.55±5.04)g/L, t=3.297, P=0.003] of follow-up. Conclusion The intensive follow-up management can significantly improve the Hb values, the rates of correction and closure rate of infants with mild anemia in the community.