Objective:To find a new method to show the subluxation of the patella that can not be displayed well by the traditional way. Methods:To measure the angel of the articular surface of the patello-femoraljoint with the wire that is parallel to the photographic bed to find the range of the angel of the x-ray tube’s centerline,then with the range of the angel ,the new axial view of patella can be taken with the supine position . Results:With this new method,the picture of the subluxation of the patella is very helpful to the clinical diagnosis. Conclusion:This new method of axial view of patella is accurate,easy to use and very useful to the diagnosis of the fracture of patella, but also useful to the estimate of the situation after operation.

OBJECTIVE:To provide references for the management and use of the donated drugs for earthquake resistance and disaster relief.METHODS:The problems appeared in the management and use of the donated drugs after the earthquake occurred on May 12,2008 in Sichuan province of China were summarized analytically and the corresponding suggestions were put forward.RESULTS & CONCLUSION:Some problems such as the turnover of the drugs,the expiration date,drug dispensing and allocation etc appeared in the management and use of the donated drugs,which should be standardized by setting related laws and regulations to make more greater use of the limited drug resource in the disaster relieving.

OBJECTIVE: To investigate the characteristics and regularity of ADR cases caused by leflunomide, and to provide reference for rational use of it. METHODS: Literatures about leflunomide-inducing ADR were retrieved from CNKI between 1994 and Apr. 2010. Those literatures were statistically analyzed in respect of patient’s age and gender, route of administration, dosage of drugs, onset time of ADR, organs and systems involved in ADR and its clinical manifestations, treatment and outcomes, etc. RESULTS: 37 pieces of literatures were obtained with standard cases of 45. The incidence of ADR cases in female(75.56%) was higher than in males (24.44%). 28 ADR cases were in 50～60 group. 39 patients were treated with leflunomide 10～30 mg once a day. After treatment, the most common gastrointestinal adverse events occurred in 1～15 d. Leflunomide-inducing ADR was digestive system reaction (75.56%) the most. Patients who took medicine less than 10 days with mild ADR need not to stop taking medicine when clinical symptoms reduced or disappeared after symptomatic treatment. Patients who took medicine more than 10 days with severe ADR need to stop taking medicine and receive symptomatic treatment. CONCLUSION: Clinical physicians should pay attention to rational use of leflunomide and ADR during treatment course to reduce the harm due to adverse events.

Sodium Ferulate(SF)is sodium salt of ferulic acid.Experimental studies showed that SF can reduce ischemical reperfusion injury of brain,heart,and liver.Clinically,SF was widely used in cardio-cerebrovascular diseases and immune system disorder.In the article,the experimental studies on SF preventing ischemical reperfusion injury of tissues were reviewed.

Objective To investigate clinical therapeutic effects after a series of improvements of multi-site combination in the simple obese patient with tumescent liposuction. Methods Before tumescence anesthetization, short-acting benzo-diazepine was used as sedative inducer. The pressure and fluid velocity of short-acting benzodiazepine were regulated and injected into deeper level of fat at first, and all of these actions decreased the pain of patients, and promote the effect of the pain tolerance. The positions of the incisions were selected to hide from view and specifically protected, which could improve looks and decrease the scar formation after operation. In later stage of operation the flaps were pressurized and slid from outside, in order to make the flaps even and smooth and to keep their thickness according to the position of the flaps and the age of the patients. Opened draining was changed to block draining after operation. Results 73 cases were taken the follow-up for 6～24 months. All cases obtained satisfactory results, except that one cases was complicated by scar hypertrophy. The changes of the circumferences were as follows: the decrease of the maximum circumference of thigh was from 2 cm to 17cm, abdomen from 3 cm to 24 cm, and buttocks from 1 cm to 3 cm. Conclusions A series of improvement of key measures enhance the clinical therapeutic effects of multi-site combination in the simple obese patient with tumescent liposuction.

Objective To correct bimaxillary protrusion by using b oth orthognathic operation and orthodontic treatment. Methods 46 bimaxillary protrusion patients, 7 male, 39 female, aged from 19 to 31 years (mean 24.2 years), were surgically corrected since 1996. Of them 31 cases underwent preoperative orthodontic treatment. Cephalometric analysis and model s urgery were performed in all patients and 4 kinds of operation methods were used to correct the deformity. All osteotomy segments were fixed with rigid internal fixation. 39 cases underwent postoperative orthodontic treatment. Re sults 34 cases had been followed-up for ranged from 12 to 72 months (mean 27.7months). All osteotomy segments healed well. There were no severe com plications and evident relapse. The maxillary osteotomy segments were moved back for average (6.3?0.9) mm and mandibular osteotomy segments for average (5.2?1 .2) mm. Both occluding relation and facial contour were satisfied. Co nclusion Bimaxillary protrusion can be satisfyingly corrected by usi ng both of orthognathic operation and orthodontic treatment.

0.05).Significant difference existed in the coliform qualification rate in the source water samples taken at various times (P0.05).However,significant difference existed in qualification rate of bacteria,fecal coliform,free chlorine residual (P

OBJECTIVE: To construct informational pharmaceutical care system(IPCS) for clinical pharmacists and to improve the level of pharmaceutical care.METHODS: By means of the latest ideas on pharmaceutical care and the support of local area network technology of Hospital Information System,the construction and running of IPCS for clinical pharmacists were illustrated using clinical cases.RESULTS: Based on the establishment of pharmaceutical record database,we could realize the integration of IPCS which included the automatic monitoring of important drugs and bacteria,clinical pharmacist consultation,information collection,information publication,information inquiry,medication counseling,establishment of specialized pharmaceutical staff and online further education,etc.CONCLUSION: The pharmaceutical care based on information platform is a good practice model for clinical pharmacy.It is the only way for clinical pharmacists to carry out further development of pharmaceutical care.

Objective:To explore the pharmaceutical care for special tumor patients performed by clinical pharmacists. Methods:Using one patient with breast cancer and hepatitis B virus infection as the example, clinical pharmacists participated in the clinical medicine therapy. Cooperating with the clinical physician, clinical pharmacists made an overall therapy regimen for the patient. On the basis of chemotherapy regimen and combining with the actual conditions of the patient, clinical pharmacists comprehensively considered the relevant therapeutic factors, such as antiviral, anti-nausea, hepatoprotective and increasing white cells therapy, and performed the corresponding regimen. In the treatment process, clinical pharmacists provided the real-time pharmaceutical care and tracking evalua-tion for the patient as well. Results: With close collaboration with clinical pharmacists and physicians, the patient obtalned perfect medicine therapy and pharmaceutical care, which made the biochemical indices ( liver enzymes, blood, hepatitis B virus load etc) tend to normal in the whole course of chemotherapy and help the patient complete the chemotherapy. Conclusion:Clinical pharmacists in-volved in clinical medicine treatment especially for special and complex diseases can make clinical medication more rational, which helps achieve the goal of treatment and reduce adverse drug reactions at the same time, and is benefit to the improvement of patient compliance and clinical medication level.

Objective To investigate the expression of nestin in fibroblasts of adult human dermis.Methods A total of 6 samples of normal human skin were collected.Immunohistochemistry and immunocytochemistry staining were used to detect the nestin expression in adult human dermis and in cultured fibroblasts of different passages(3rd,5th,7th,10th,and 12th passages,respectively) in vitro.Nestin positive cells were counted to evaluate the expression quantity and intensity.Results There were 103.3?67.4 fibroblasts per square millimeter(mm~2) of adult human dermis,and the nestin positive fibroblasts accounted for(9.5?3.0)% of total amount.The amount of nestin positive fibroblasts in vitro was obviously higher than that in vivo.Significant difference was observed in the amount of nestin expression among different passages(P