1.Research on calculation of the regional cerebral blood volume based on minimum mean square error method.
Jie CHEN ; Ying LI ; Rongren WANG ; Renjie HE ; Liyun RAO
Journal of Biomedical Engineering 2014;31(6):1207-1211
In this paper, the Fourier transform based minimum mean square error (FT-based MMSE) method is used to calculate the regional cerebral blood volume (rCBV) in magnetic resonance (MR) perfusion imaging, and the method is improved to handle the existing noise in the imaging process. In the experiments with signal-to-noise ratio (SNR) of 50 dB, the rCBV values were compared with the results using MMSE method. The effects of different SNRs on the estimation of rCBV were analyzed. The experimental results showed that MMSE was a simple way to filter the measurement noise, and could calculate rCBV accurately. Compared with other existing methods, the present method is not sensitive to environment, and furthermore, it is suitable to deal with the perfusion images acquired from the environment with larger SNR.
Blood Volume
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Brain
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blood supply
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Fourier Analysis
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Humans
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Magnetic Resonance Angiography
2.Recommendation of a highly sensitive method for measuring hemoglobin in hemolytic test.
Wangping HU ; Yingying HU ; Fuying FENG ; Jinyao HUANG ; Rongsheng ZHANG ; Rongren CHEN ; Changshao ZHOU ; Hailin WANG
Journal of Biomedical Engineering 2007;24(3):664-666
In this paper is recommended a highly sensitive and reagent-safe method to determine plasma heamoglobin (FHb) in viscacha hemolytic test. The 2,4-dichlorophenol method (2,4-DCP) of Trinder reaction has been improved. The performance of 2,4-DCP is verified. The sensitivity of 2,4-DCP is 2.39 times that of phenol method. It is well used with run precision and day-to-day precision. The reaction color is stable. The reference value FHb is 1-36.7 mg/L. Sodium citric is an excellent anticoagulant liquid to keep erythrocyte. The 2,4-DCP method is neither carcinogenic nor poisonous;it is suitable for viscacha hemolytic test in clinical and biomedical engineering.
Chlorophenols
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Coombs Test
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methods
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Hemoglobins
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analysis
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Hemolysis
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Humans
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Sensitivity and Specificity