1.Value of strain ratio in differentiating benign and malignant breast lesions of BI-RADS-US Ⅳ
Xiangdong HU ; Yanhong FENG ; Yu GUI ; Yuelong WANG ; Rongqiang LEI ; Linxue QIAN
Chinese Journal of Ultrasonography 2012;21(6):488-491
ObjectiveTo assessment the value of strain ratio(SR) in differentiating benign and malignant breast lesions of BI-RADS Ⅳ diagnosed by conventional ultrasound.MethodsElastosonography was performed on 64 patients with breast lesions of BI-RADS Ⅳ diagnosed by conventional ultrasound.SR (strainnormal neighboring tissues /strainbreast lesion) was calculated by the software equipped with the ultrasonic machine.Pathology of the lesions after biopsy or operation was considered as standard,SRs of benign and malignant breast lesions were compared with independent-samples t test.The diagnostic value of SR was evaluated by receiver operating characteristic (ROC) curve analysis.Results SRs of 34 benign breast lesions and 30 malignant breast lesions were 2.85 ± 1.30 and 5.03 ± 2.50 respectively,there was significant difference between them( t =- 4.29,P =0.000).Area under the curve of diagnosing benign and malignant of breast lesions was 0.875 for SR( P <0.0001).If the cut-off point of SR was 3.26,the sensitivity in differentiating breast lesions was 83.33%,while the specificity was 82.35%.Conclusions SR is a helpful elasticity parameter for differentiating benign and malignant breast lesions of BI-RADS Ⅳ diagnosed by conventional ultrasound.
2.Study on correlation of androgen and androgen receptor with coronary heart disease in elderly men
Jian CAO ; Xiaoying LI ; Bingpo ZHU ; Hao WANG ; Shasha ZHAO ; Ke MIAO ; Lan XUE ; Rongqiang ZHANG ; Xinli DENG ; Yu DING ; Zhiqin GUO ; Peizhen LI ; Huiming LI ; Hui WU ; Fangling MA
Chinese Journal of Geriatrics 2008;27(12):901-904
Objective To investigate the changes of sex hormone and androgen receptor levels and evaluate the relationship of the sex hormones and androgen receptor with coronary heart disease (CHD) in elderly men. Methods A cross-sectional study was performed in 539 elderly men, including 400 healthy people aged 62-92 years and 139 CHD patients aged 60-88 years. The plasma concentrations of total testosterone (TT), free testosterone (FT), dehydroepiandrosterone sulfate (DHEAS), sex hormone binding globulin (SHBG), estradiol (E2), luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were measured. The androgen receptor (AR) level was tested by flow cytometry. Results The fluorescence intensity of DHEAS, TT, SHBG, FT and AR were significantly lower in CHD group than in healthy group (P<0.01);however, FSH and E2 in CHD group were higher(P(0.01). Age was negatively correlated with TT(r=-0.28,P<0.01) and FT (r=-0.17,P<0.05), and positively correlated with SHBG(r=0.14,P<0.05) and E2 (r=0.33, P<0.01). AR fluorescence intensity was negatively correlated with systolic blood pressure (r=-0.12,P<0.01). Logistic regression analysis indicated that TT (OR=1.065,9% CI: 1.012~1.121,P<0.05), SHBG(OR=0.994,95% CI:0.990~0.998,P<0.01) and AR (OR=0.971,95%CI:0.956~0.986, P<0.01)were significantly associated with CHD in elderly male patients. Conclusions The levels of DHEAS, TT, SHBG, FT and AR are lower in elderly men with CHD than in elderly healthy men;however, the FSH and E2 concentrations are higher. Low levels of TT, SHBG and AR may be the independent risk factors for CHD in elderly men.
3.Establishment of a non-venous bypass orthotopic liver transplantation model in Bama miniature pigs
Qiao SU ; Zhenyu YU ; Wenwen LI ; Linsen YE ; Tianxing DAI ; Rongpu LIANG ; Rongqiang LIU ; Guozhen LIN ; Guangyin ZHAO ; Wuguo LI ; Guoying WANG ; Guihua CHEN
Organ Transplantation 2019;10(1):55-
Objective To establish a non-venous bypass orthotopic liver transplantation model in Bama miniature pigs with high repeatability and stability. Methods Twelve Bama miniature pigs were randomly divided into the donor group (
4.Influenza-associated-excess-hospitalization in children,Wuxi city,Jiangsu province,2005-2010
Luzhao FENG ; Fangrong FEI ; Sa LI ; Yanhua QIAN ; Rongqiang ZU ; Hongjie YU
Chinese Journal of Epidemiology 2014;(6):699-703
Objective To estimate the rates due to influenza-associated-excess-hospitalization in children aged 0-14 years in Wuxi city,Jiangsu province in 2005-2010. Methods We collected data on hospitalization due to influenza,pneumonia and other respiratory diseases from fourteen 2nd level or above hospitals in Wuxi,as well as data on influenza virological surveillance in southern China to fit the negative binomial regression models,to estimate the rate on influenza-associated-excess hospitalization. Results During 2005-2010,an average annual hospitalization rate appeared as 91.6‰(79.2‰-99.3‰). Among the total hospitalization eases,respiratory diseases accounted for 54.2%,while both influenza and pneumonia accounted for 38.1%. The average annual influenza-associated-excess-hospitalization rates due to influenza and pneumonia appeared as 1.28‰(95%CI:0.29‰-4.84‰),while 2.18‰(95%CI:0.61‰-6.79‰) due to respiratory diseases. In 2009,A(H1N1)pdm induced influenza pandemic caused 993 excess hospitalizations due to influenza/pneumonia and 1 042 excess hospitalizations due to respiratory diseases,with rates as 1.14‰ and 1.20‰ respectively. Conclusion Both seasonal and pandemic A(H1N1)pdm influenza caused considerable burden on hospitalization in children aged 0-14 years in Wuxi.
5.Practice of a hemodialysis alliance in the context of closed-loop hospital management
Jing QIAN ; Mengjing WANG ; Chuhan LU ; Ping CHENG ; Li NI ; Wei LIU ; Bihong HUANG ; Zhibin YE ; Zhenwen YAN ; Qianqiu CHENG ; Chen YU ; Aili WANG ; Ai PENG ; Wei XU ; Chunlai LU ; Dandan CHEN ; Xiuzhi YU ; Liyan FEI ; Jun MA ; Jialan SHEN ; Junhui LI ; Ying LI ; Lingyun CHEN ; Weifeng WU ; Rongqiang YU ; Lihua XU ; Jing CHEN
Chinese Journal of Hospital Administration 2022;38(8):595-599
Closed-loop hospital management can effectivly cope with the COVID-19 pandemic. In order to ensure the continuity of treatments for hemodialysis patients under closed-loop management and minimize possible medical and infection risks, Huashan Hospital affiliated to Fudan University and 9 hospitals in Shanghai established a hemodialysis alliance in January 2021.The alliance optimized hemodialysis resources within the region through overall planning by preparing sites, materials and personnel shifts in advance, and establishing management systems and work processes to ensure that patients could be quickly and orderly diverted to other blood dialysis centers for uninterrupted high-quality hemodialysis services, in case that some hemodialysis centers in the alliance under closed-loop management.From November 2021 to April 2022, 317 of 1 459 hemodialysis patients in the alliance were diverted to other centers for treatment, accumulating 1 215 times/cases of treatments without obvious adverse reactions. The practice could provide a reference for medical institutions to quickly establish mutual support mode under major public health events.
6.Influenza-associated-excess-hospitalization in children, Wuxi city, Jiangsu province, 2005-2010.
Luzhao FENG ; Fangrong FEI ; Sa LI ; Yanhua QIAN ; Rongqiang ZU ; Hongjie YU
Chinese Journal of Epidemiology 2014;35(6):699-703
OBJECTIVETo estimate the rates due to influenza-associated-excess-hospitalization in children aged 0-14 years in Wuxi city,Jiangsu province in 2005-2010.
METHODSWe collected data on hospitalization due to influenza, pneumonia and other respiratory diseases from fourteen 2nd level or above hospitals in Wuxi, as well as data on influenza virological surveillance in southern China to fit the negative binomial regression models, to estimate the rate on influenza-associated-excess hospitalization.
RESULTSDuring 2005-2010, an average annual hospitalization rate appeared as 91.6‰ (79.2‰ -99.3‰). Among the total hospitalization eases, respiratory diseases accounted for 54.2%, while both influenza and pneumonia accounted for 38.1%. The average annual influenza- associated-excess-hospitalization rates due to influenza and pneumonia appeared as 1.28‰ (95% CI:0.29‰ -4.84‰), while 2.18‰ (95% CI:0.61‰ -6.79‰) due to respiratory diseases. In 2009, A (H1N1) pdm induced influenza pandemic caused 993 excess hospitalizations due to influenza/pneumonia and 1 042 excess hospitalizations due to respiratory diseases, with rates as 1.14‰ and 1.20‰ respectively.
CONCLUSIONBoth seasonal and pandemic A(H1N1)pdm influenza caused considerable burden on hospitalization in children aged 0-14 years inWuxi.
Adolescent ; Child ; Child, Preschool ; China ; epidemiology ; Female ; Hospitalization ; statistics & numerical data ; Humans ; Infant ; Infant, Newborn ; Influenza, Human ; epidemiology ; Male
7.Epidemiological characteristics of traumatic spinal cord injury in China in 2018
Dingjun HAO ; Baorong HE ; Liang YAN ; Jinpeng DU ; Xiao QI ; Shicheng YU ; Jiaojiao ZHANG ; Wenjing ZHENG ; Rongqiang ZHANG ; Dageng HUANG ; Junsong YANG ; Ming ZHU ; Jiawei OUYANG ; He ZHAO ; Keyuan DING ; Haodong SHI ; Yang CAO ; Ying ZHANG ; Qinghua TANG ; Yuan LIU ; Zilong ZHANG ; Yuhang WANG ; Ye TIAN ; Hao CHEN ; Lulu BAI ; Heng LI ; Chenchen MU ; Youhan WANG ; Xiaohui WANG ; Chao JIANG ; Jianhua LIN ; Bin LIN ; Shunwu FAN ; Lin NIE ; Jiefu SONG ; Xun MA ; Zengwu SHAO ; Yanzheng GAO ; Zhong GUAN ; Yueming SONG ; Weihu MA ; Qixin CHEN
Chinese Journal of Trauma 2021;37(7):618-627
Objective:To analyze the incidence and epidemiological characteristics of traumatic spinal cord injury in China in 2018.Methods:Multi-stage stratified cluster sampling was used to randomly select hospitals capable of treating patients with spinal cord injury from 3 regions,9 provinces and 27 cities in China to retrospectively investigate eligible patients with traumatic spinal cord injury admitted in 2018. National and regional incidence rates were calculated. The data of cause of injury,injury level,severity of injury,segment and type of fracture,complications,death and other data were collected by medical record questionnaire,and analyzed according to geographical region,age and gender.Results:Medical records of 4,134 patients were included in this study,with a male-to-female ratio of 2.99∶1. The incidence of traumatic spinal cord injury in China in 2018 was 50.484 / 1 million (95% CI 50.122-50.846). The highest incidence in the Eastern region was 53.791 / 1 million (95% CI 53.217-54.365). In the whole country,the main causes of injury were high falls (29.58%),as well as in the Western region (40.68%),while the main causes of injury in the Eastern and Central regions were traffic injuries (31.22%,30.10%). The main injury level was cervical spinal cord in the whole country (64.49%),and the proportion of cervical spinal cord injury in the Central region was the highest (74.68%),and the proportion of lumbosacral spinal cord injury in the Western region was the highest (32.30%). The highest proportion of degree of injury was incomplete quadriplegia (55.20%),and the distribution pattern was the same in each region. A total of 65.87% of the patients were complicated with fracture or dislocation,77.95% in the Western region and only 54.77% in the Central region. In the whole country,the head was the main combined injury (37.87%),as well as in the Eastern and Central regions,while the proportion of chest combined injury in the Western region was the highest (38.57%). A total of 32.90% of the patients were complicated with respiratory complications. There were 23 patients (0.56%) died in hospital,of which 17(73.91%) died of respiratory dysfunction. Conclusions:The Eastern region of China has a high incidence of traumatic spinal cord injury. Other epidemiological features include high fall as the main cause of injury cervical spinal cord injury as the main injury level,incomplete quadriplegia as the main degree of injury,head as the main combined injury,and respiratory complications as the main complication.
8.Clinical comparative study of naked eye 3D versus 2D thoracoscope in minimally invasive esophagectomy
HUANG Kenan ; DING Xinyu ; CHEN Zihao ; WEI Rongqiang ; CHEN Yu ; XU Zhifei ; TANG Hua
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2020;27(04):441-445
Objective To investigate the safety and efficacy of naked eye 3D thoracoscopic surgery in minimally invasive esophagectomy. Methods Clinical data of 65 patients, including 50 males and 15 females aged 47-72 years, with esophageal cancer who underwent minimally invasive thoracoscopic esophagectomy from October 2018 to April 2019 were retrospectively analyzed. Patients were divided into two groups according to different surgical methods including a naked eye 3D thoracoscopic group (group A: 30 patients) and a traditional 2D thoracoscopic group (group B: 35 patients). The effects of the two groups were compared. Results The operation time in the group A was significantly shorter than that in the group B (P<0.05). The number of dissected lymph nodes in the group A was more than that in the group B (P<0.05). The thoracic drainage volumes on the 1th-3th days after operation in the group A were significantly larger than those in the group B (P<0.05), but there was no significant difference between the two groups on the 4th-5th days after operation (P>0.05). The indwelling time in the group A was longer than that in the group B (P<0.05). Postoperative hospital stay, pulmonary infection, arrhythmia, anastomotic leakage, and recurrent laryngeal nerve injury were not significantly different between the two groups (P>0.05). Conclusion Naked eye 3D thoracoscopic surgery for minimally invasive esophagectomy is a safe and effective surgical procedure. Compared with traditional 2D minimally invasive thoracoscopic surgery, it is safer in operation and more thorough in clearing lymph nodes. The operation is more efficient and can be promoted.
9.Clinical study of 3D versus 2D thoracoscopic surgeries in uniportal lobectomy
Kenan HUANG ; Xinyu DING ; Zihao CHEN ; Rongqiang WEI ; Yu CHEN ; Zhifei XU ; Hua TANG
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2020;27(07):770-774
Objective To investigate the safety and efficacy of 3D thoracoscopic surgery in uniportal lobectomy. Methods Clinical data of 248 patients with lung cancer who underwent uniportal thoracoscopic lobectomy in our hospital from September 2018 to May 2019 were retrospectively analyzed. Patients were divided into two groups according to different surgical methods, a 3D thoracoscopic group (76 patients, including 52 males and 24 females with an average age of 58.59±7.62 years) and a 2D thoracoscopic group (172 patients, including 102 males and 70 females with an average age of 57.75±8.59 years). Statistical analysis of clinical and pathological data, lymph node dissection, surgical complications, postoperative hospital stay, etc was performed. Results Compared with the 2D thoracoscopic group, the 3D thoracoscopic group had shorter operation time, more lymph nodes dissected and pleural effusion on the first day after operation (P<0.05). There was no significant difference in the postoperative chest tube duration, postoperative hospital stay, incidence of pulmonary infection, arrhythmia, bronchopleural fistula, or recurrent laryngeal nerve injury between the two groups. Conclusion Compared with the traditional 2D thoracoscopic minimally invasive surgery, uniportal lobectomy with 3D thoracoscopic surgery is safer and more efficient during operation, and lymph node dissection is more thorough, which is worth promoting.