ObjectiveTo analyze the influencing factors of the blood pressure fluctuation during the perioperative period of pheochromocytoma,and discuss the ways to improve the hemodynamics.Methods The clinical data of patients with pheochromocytoma who had received operation from 2000 to 2010 werestudied retrospectively.The influencing factors of perioperative blood pressure fluctuation were analyzed by statistical methods including Pearson correlation analysis and Logistic regression.ResultsAccording to Pearson correlation analysis,the influencing factors of the highest fluctuation value of the systolic blood pressure ( △ SBP) during the operation included the preoperative highest systolic blood pressure (r =0.196,P =0.013 ),the content of preoperative 24-hour urine epinephrine ( r =0.207,P =0.008 ) and the lost blood volume during the operation (r =0.253,P=0.003).Logistic regression analysis showed that the postoperative persisting hypotension was influenced by the content of preoperative 24-hour urine norepinephrine(OR =1.273,P =0.002) and preoperative preparation duration(OR =0.921,P =0.034);the risk factors of postoperative hypertension were residual tumor (OR =16.920,P =0.001 ) and the preoperative hematocritchange(OR =1.467,P =0.018).ConclusionsIn spite of the adequate preoperative preparation,great changes of blood pressure would still occur during the perioperative period of pheochromocytoma,and it is influenced by many factors.Corresponding measures aiming to these factors should be taken to decrease the perioperative blood pressure fluctuation and surgical risks.

Objective:To discuss the clinical efficacy of Shenghua Decoction combined with conventional western medicine therapy in treatment of polycystic ovarian syndrome with blood-insufficiency congealing-cold and blood-stasis syndrome. Methods:A total of 140 polycystic ovarian syndrome patients with blood-insufficiency congealing-cold and blood-stasis syndrome were selected from January 2018 to December 2019 in our hospitals, and were divided into observation group and control group according to the random indicator method, 70 cases in each group. The control group received ethinylestradiol and cyproterone acetate tablets treatment, and Shenghua Decoction was added based on the control group’s treatment in the observation group. Changes in the TCM syndrome score, modified Ferriman-Gallway (mF-G) of hirsutism, Rosenfield of acne, Testosterone (T), Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) levels detected by ELISA of two groups were observed. The adverse events were recorded and the clinical efficacy was evaluated. Results:The effective rate of the observation group was 88.6% (62/70), which was significantly higher than control group of 60.0% (42/70) ( χ2=14.957, P<0.001). After treatment, mF-G, Rosenfield and TCM Syndrome Scores in the observation group were significantly lower than those in the control group ( t=6.524, 3.111, 2.196, P<0.01 or P<0.05). After treatment, the levels of FSH [(5.16 ± 1.76) IU/L vs. (7.19 ± 1.06) IU/L, t=2.530], LH [(6.12 ± 1.88) IU/L vs. (8.03 ± 1.78) IU/L, t=2.403], T [(1.34 ± 0.32) μg/L vs. (1.80 ± 0.36) μg/L, t=7.080] in the observation group were significantly lower than those in the control group ( P<0.05 or P<0.01) Conclusion:The Shenghua Decoction showed beneficial effect for the patients with polycystic ovarian syndrome with blood-insufficiency congealing-cold and blood-stasis syndrome.

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Effective and objective assessment technique is lacked for diagnosis and evaluation of Parkinson's disease at present. In recent years, surface electromyography (sEMG) as an objective and quantitive assessment method, has been used to study the neuromuscular status and motor function of Parkinson's disease. This article reviewed related literatures in nearly 10 years in order to further understand the current application of sEMG.

ole on the development of septic AKI. It's useful to decrease the incidence of AKI by elevating the blood pressure and C1, but super-normal goal won't work better.

Objective: To compare the balance ability between normal people and non-specific low back pain (nsLBP) patients and explore the relationship between balance ability and muscle function in nsLBP patients. Method: Ten nsLBP patients as nsLBP group and 10 age and gender-matched healthy control subjects as control group were investigated. Posturography on balance platform and surface electromyography (sEMG) were performed to assess all the subjects' function of equilibrium and muscle activities of erector spinea(ES), muhifidus(MF), abdominal external oblique (EO), hamstring (HS) and maximal gluteus (MG) bilaterally. Result: The nsLBP subjects had greater sway on anterior-posterior direction (Y-speed and Y-extension, P=0.05) on feet-together posture and bigger main axis (P=0.023) on nature standing with eyes closed when compared with controls. The iEMG ratios of right MG in nature standing (eyes closed)/ nature standing (eyes open) and feet-together (eyes open)/nature standing (eyes open) in control group were significant higher than that in nsLBP group (P=0.03 and P=0.013). Conclusion: Balance evaluation combined with sEMG measurement on trank and lower limb muscles provided some quantitative information about functional deficits such as pestural control and muscle activities in nsLBP patients. This relationship should be emphasized in prevention and rehabilitation of nsLBP.

Objective To analyze the features of surface electromyography (sEMG) signal of the tibial anterior muscle and gastrocnemius muscle in the stroke patients when sitting and standing.Methods Fifteen stroke patients and fifteen normal subjects were involved in this study. All subjects were asked to stand up and sit down. It repeated five times continuously. The electromyographic signals were collected by surface electrode and then processed by linear time and frequency domain method.Results In sitting position, tibial anterior muscle had significant differences in mean power frequency and median frequency ( P<0.05) when the paretic and non-paretic lower limb, the non-paretic lower limb in stroke patients and in normal subjects were compared. The gastrocnemius muscle had notable differences ( P<0.05) in root mean square when the non-paretic lower limb in stroke patients and in normal subjects were compared. In standing position, tibial anterior muscle also had significant differences in root mean square and integrated electromyography ( P<0.05) as the same frequency domain comparing as above. The gastrocnemius muscle had notable differences on time domain, when the paretic and non-paretic lower limb, the paretic lower limb in stroke patients and the limb in normal subjects were compared ( P<0.05 or P<0.01).Conclusion sEMG is a brief, applied, feasible assessment method in rehabilitation.

The self-microemulsion formulation of potassium dehydroandrographolidi succinas (PDS) has been optimized and the performance in vitro has been evaluated preliminary. Kinds of prescription accessories were screened by solubility based on the emulsifying result and efficiency, particle size of emulsions. The optimal formulation composition and compatibility proportion were determined by orthogonal design and pseudo-ternary phase diagrams. The appearance, particle size, Zeta potential and stability of this formulation were also investigated. The optimized prescription of PDS was 10% MCT, 40% Tween-20 and 50% glycerol. It can spontaneously form a transparent pale blue opalescent emulsion with emulsification time 31.27 s, particle size 37.1 nm, Zata potential -17.4 mV and good stability.

Objective: To explore the change of fractional exhaled nitric oxide (FeNO) and its correlation with forced expiratory volume in the ifrst second (FEV1), the ifrst second forced expiratory volume percentage of forced vital capacity (FEV1/FVC) in bronchial asthma and chronic obstructive pulmonary disease (COPD). Methods: FeNO, FEV1 and FEV1/FVC were measured in 57 suspected asthmatics (21 acute onsets, 12 non-acute and 24 non-asthma), 38 COPD patients (25 acute exacerbations and 13 stable stages) and 26 healthy subjects. Results: In the 57 suspected asthmatic patients, when the optimal cut off value of FeNO was 20.15 PPb, which was used to diagnose asthma and differentiate asthma and non-asthma, the positive predictive value, the negative predictive value, the sensitivity and the speciifcity was 94.1%, 95.7%, 97.0%, and 91.7% respectively. hTere was signiifcant difference in the FeNO level between the 33 asthmatics and 26 healthy subjects (P<0.05). There was also significant difference in the FeNO level between the acute onset and the non-acute (P<0.05), but not in the FEV1 and FEV1/FVC level (bothP>0.05). hTere was no signiifcant correlation between FeNO and FEV1, FEV1/FVC in patients with asthma (r=-0.186,-0.236, bothP>0.05). hTere was signiifcant difference in the levels of FeNO, FEV1 and FEV1/FVC between the 38 COPD patients and the 26 healthy subjects (all P<0.05), and also between the 25 acute exacerbations and 13 stable COPDs (allP<0.05), but not between the 13 stable COPDs and 26 healthy subjects (allP>0.05). FeNO was not correlated with FEV1 and FEV1/FVC level in COPD patients (r=-0.167,-0.285, bothP>0.05). Conclusion: FeNO level is increased obviously in patients with asthma. hTe optimal cut off value of FeNO at 20.15 PPb can differentiate asthma and non-asthma with high sensitivity and speciifcity. FeNO is higher for the acute onset than non-acute, which may be useful to evaluate the control degree. FeNO level is increased in COPD patients in the acute exacerbations, but there is no change in stable COPD patients compared with the healthy subjects.