Objective To assess the therapeutic effect of losartan on cardiac remodeling for patients with idiopathic dilated cardiomyopathy (IDCM). Methods From Jan.1997 to Dec.2002,UCG was performed in 56 patients with IDCM.They were divided into two groups.The first group of 30 patients were treated with losartan (50mg) plus ?-receptor blocker per day.The other group of 26 patients received standard conventional therapy,including cardiac,diuretic and potassium-spring.All patients were interviewed once a month for the following 6 months.The results of UCG were based on the examination taken by the end of 3 months and 6 months. Results In the first group,UCG improved significantly ( P 0.05). Conclusion Losartan may be effective to restrict the heart reconstruction and reduce the heart weigh and improve the heart function after 3-month therapy and may be more effective after 6 months of therapy.

Objective To investigate the afflication of non-humidified low flow nasal oxygen inhalation in the ICU patients. Methods Four hundred patients hospitalized in ICU and needing continuous low-flow oxygen inhalation for more than 24 h were randomly divided into experiment group and control group equally.The experiment group were managed with dried humidification bottle oxygen inhalation and the control group conventional humidified bottle oxygen inhalation.The two groups were compared in terms of 24 h respiratory reactions,bacterial contamination of the humidified bottle,complaints of patients about oxygen inhalation noises and time for nurses to change the humidified bottles.Results The two groups had no significant difference in adverse symptoms(all P>0.05).The rate of bacterial contamination in the experimental group was significantly lower than the control group(P<0.05),the noises were lower and the time for changing the bottle shorter(P<0.05).Conclusion Non-humidified low flow nasal oxygen inhalation in ICU patients is good for reducing the rate of bacterial contamination of humidified bottle and lowering workload and oxygen-inhaling noises.