Objective To explore the effects of hand hygiene management on hand washing compliance of staff members and infection rates in Burn Unit.Methods From April 201 5 to October 201 5,40 staffs in Burn Unit received the hand hygiene management intervention,including perfecting facilities of hand hygiene, carrying out propaganda and standardizing the supervision,and so on.The hand washing compliance of staffs and infection rates in burn unit were observed before and after interventions.Results Before interventions,the hand hygiene compliance of doctors,nurses,nursing assistants,cleaning workers were 41 .5%,45.7%, 31 .0%,29.0%,lower than 88.8%,91 .7%,74.9%,68.8% after the interventions,and all staffs improved the compliance of hand hygiene (P <0.01 ).Before and after interventions,the compliance in doctors and nurses was higher than that of caregiver and cleaner (P <0.01 ).The hospital infection rate was reduced from 1 3.2% before interventions to 6.8% after interventions(P <0.05 ).Conclusions To make effective hand hygiene management measures can improve the hand hygiene compliance of staffs in Burn Department and effectively reduce the hospital infection rate.