Heterotopic ossification is the abnormal formation of true bone within extraskeletal soft tissues, which frequently showing a predilection instead for fascia, tendons, and other mesenchymal soft tissues. This paper summarized differential types and quantities of regulatory proteins expression at different stages of heterotopic ossification by proteomics techniques, and screened differential expression of functional proteins at different time points. Further more, identificated and validated certain proteins, which helpful to discovery new regulatory proteins and explore the mutual relationships among the proteins. Proteomics has extensive applications in regulatory proteins research of post-traumatic heterotopic ossification, can further elucidate the mechanism of post-traumatic ectopic bone formation and search for new regulatory biomolecule regulatory sites.

Objective: To design device to measure D/T index which is used for evaluation of arteriosclerosis. Methods:By calculating the detected date of blood pressure values, pulse pressure, pulse rate, pulse patterns and SpO2 on the extremities, we get a set of analytical data in the system in order to analyze the arteriosclerosis situations. Results: The device use the ECG signal as it based and modulated signal, the computer process the date of blood pressure and SpO2, then output the result by the display and printing systems. Conclusion:The device provides an effective noninvasive detection means for extremity vascular.

Perthes disease is a hip lesion caused by vascular disorders in the femoral head of children.Although the disease is a self-limited disease,but often residualvary degrees of femoral head deformity,leading to early osteoarthritis.It is currently believed that the lesions of Perthes disease are mainly located in the femoral head.However,some studies demonstrated that patients with Perthes disease also appearvary degrees of acetabular morphological changes.In recent years,the acetabular retroversions were found in 31-60％ of patients with Perthes disease.The acetabular retroversion is a pathological anatomical variation of the acetabulum in the horizontal plan.It is related to the occurrence of the femoracetabular impingement and osteoarthritis.Many studies showed that the patients with poor prognosis (Stulberg Ⅲ,Ⅳ or Ⅴ) are associated with a higher prevalence of acetabular retroversion.The grading and the age of onset of Perthes disease are important factors affectingprognosis.Although existing studies illustrate that the lateral column grading,gender and age are not associated with the acetabular retroversion of Perthes disease significantly,the cases of the studies are limited and further researches are expected.Surgery containment therapy is an important wayto treat Perthes disease.The pelvic osteotomy can directly change the shape of the acetabulum and cause the acetabular retroversion,which result inthe femoracetabular impingement.The acetabular retroversion should be avoided as much as possible intraoperatively.Further research should be focused on whether the surgical interventions and the subsequent biomechanical changes could induce the acetabular retroversion.The cause of the acetabular retroversion in patients with Perthes disease is unclear.In order to elucidate the occurrence and development of acetabular retroversionin Perthes disease,some scholars found thataccompanying femoral head deformity,acetabular anteversion angleand inclinationdecreased significantly,and thecoverage angle in the superior,posterior,and inferior quadrants alsogradually reduced in animal studies.This is similar to clinical observations.This article reviews the progress of acetabular retroversion in Perthes disease by summarizing the relevant literatures.We hope to givenew insights for the etiology and pathology of Perthes disease,and provide new ideas for the treatment and prevention of the femoracetabular impingement and early osteoarthritis.

With the aging of the Chinese society and the population, the incidence of hip fractures in the elderly is increasing significantly. Elderly patients have various basic diseases and decreased organ compensatory capacity, which increase the risks related to surgery and anesthesia, increase the incidence of postoperative complications and mortality, and affect the recovery process of patients. Malnutrition is one of the main causes of hip fractures in elderly patients, and it is also a major factor predicting the prognosis of patients. Elderly patients with hip fractures are considered at high risk of malnutrition. Malnutrition can lead to adverse clinical outcomes, such as increased mortality and complications, prolonged hospital stays, and increased hospital costs. Elderly patients with hip fracture should be routinely screened for nutritional risk. Those with malnutrition or nutritional risk, should be given nutritional support treatment. And conduct assessments and optimizations of nutritional support treatmentby observing the prognosis indicators such as complication rate, mortality, and rehabilitation status. At present, orthopedic surgeons who are the main body of elderly hip fracture treatment do not pay enough attention to the nutritional status of patients. Many elderly hip fracture patients undergo surgery while their malnutrition status has not improved. Therefore, it is important to improve their prognosis that strengthen the perioperative nutritional management of elderly patients with hip fracture. Domestic research on the nutritional status of elderly hip fracture patients started late. Many medical institutions have not carried out routine nutritional screening and active nutritional support treatment for elderly hip fracture patients, and there is also a lack of relevant clinical research and data statistics in the nutritional support and treatment of elderly patients with hip fractures. This article describes the current research status of nutritional risk screening and nutritional support treatment for elderly patients with hip fracture at home and abroad. However, due to differences in ethnicity, lifestyle, religious culture, and eating habits in various regions, foreign research data may not be suitable for domestic patients. Therefore, this article provides a reference for the research on perioperative nutritional screening and nutritional treatment of elderly hip fracture patients, and establishes a nutritional management plan suitable for elderly hip fracture patients in China.

Objective To study the distribution and the characteristic of elbow fractures in children according to the age,sex,year,season and anatomical location.Methods The data of pediatric elbow fractures which were treated either in outpatient department or hospitalized in the First Affiliated Hospital of Guangxi Medical University between January 2011 and December 2016 were collected.The distribution and characteristics of the fractures were analyzed by using SPSS 18.0 software and Excel 2010.Results A total of 613 patients with elbow fractures (628 different anatomical sites) were registered.The incidence seemed to increase by each year.Among them,414 cases were male and 199 cases were female (male/female ratio 2.08 ∶ 1.00).There were 3 distinct peaks which were respectively at the ages of 1,3 and 5.The fractures happened frequently from April to October.The most common type was supracondylar fracture of humerus(71.29％,437/613 cases),followed by lateral condylar fracture of humerus(14.68％,90/613 cases),olecranon fracture(3.26％,20/613 cases) and radial neck fracture (2.28％,14/613 cases).The most common cause of injury was falling on the same level (67.54％,414/613 cases),followed by dropping from heights (16.64％,102/613 cases),then sports injury (7.83％,48/613 cases),traffic accidents (5.55％,34/613 cases) as well as some intentional injuries (0.65％,4/613 cases).Conclusions The highest incidence of elbow fracture was found in children around 1 year,and 3-6 years.Boys are more affected than girls,probably attributed to their active nature.Fractures are more frequent in summer in which supracondylar fracture of humerus is the most common type.Most fractures occur after falling on the same level,indicating how easy it is to get injured in children.So careful examination is necessary to all the pediatric cases who came with a history of fall.Attention should be paid to intentional injuries especially so as to rule out if the cases belong to brutal abuse.

The Kickstand technique is an extension added to the basic frame of modern external fixation to elevate an affected extremity. It is an affordable and modified external fixation in orthopedic trauma. Orthopedic physicians use this technique to prevent formation of pressure sores and relieve swelling in lower extremity of patients who require prolonged bed rest, because this technique makes the heel apart from the supporting surface and promotes circulation of venous blood lymph fluid. This paper briefly introduces the development of this technique and its efforts to improve quality of care and solve a clinical problem. To relieve the burden of healthcare for pressure sores and swelling in an affected lower extremity after surgery, this technique should be popularized.