Invasive fungal infections(IFI) is significantly increasing in the neonatal intensive care unit recent years.The characteristics of IFI are low diagnosis rate,high mortality and being prone to involve in the nervous system.In this paper,the epidemiology,pathogens,risk factors,diagnosis,treatment and prevention of neonatal IFI are reviewed to improve the understanding of this disease.

Humans ; Spinal Fractures ; classification ; diagnosis ; therapy ; Thoracic Vertebrae ; injuries ; surgery

Humans ; Integrative Medicine ; Medicine, Chinese Traditional ; methods

The application management of surgical instrument is introduced from five aspects including risk control, operation rules, quality inspection and metering management, periodical maintenance and prompt service.

Objective To improve the health of women and children,we built a medical research platform with maternal and child health characteristics and feature.Methods Since January 2011,we build the medical research platform of Huaian MCH through the following three aspects.①To firmly establish the thought of Science and technology to revitalizing the hospital and outstand technical innovation.② built a medical research platform with maternal and child health characteristics and feature.③To focus on construction of Research platform.Results After building research platform,the total number of published papers or high-level papers and the total number or level of the Research Projects and the New Technology Award are significantly higher.Many disciplines and specialist technical levels have been improved in our MCH.Neonatal Medical Center and Children's Health Center have upgraded to Provincial Maternal and Child Healthcare key disciplines.The department of women healthcare has upgraded to Provincial Maternal and Child Healthcare key disciplines construction unit.In 2012,our MCH got top 30 of comprehensive index ranking in operation and development of the National Maternal and Child Health agencies.Conclusion Building the medical research platform with the characteristics of maternal and child healthcare,can improve maternal and child healthcare service quality and level of clinical services,and promote the development of the hospital's overall strength,thereby increasing the ability of hospitals to protect the health of women and children.

Objective To evaluate the effects of three-dimensional conformal radiation therapy (3DCRT) on the local control and survival of patients with local recurrence or metastasis in colorectal cancer. Methods Twenty-three patients with local recurrence or metastasis in colorectal cancer were irradiated by 3DCRT. The regimen was: total dose 40-45?Gy, 5-7?Gy/f, 1f/2d. Results Of the 23 patients, 8 achieved CR and 9 PR with a total response rate of 74%(17/23). The overall 1-, 2-and 3-year survival rates were 78%,52% and 30%. Conclusion 3DCRT is able to prolong the survival and improve the life quality of patients with local recurrence or metastasis in colorectal cancer.

Objective To increase the awareness of lung cancer complicating thrombosis disease(TD).Methods From 1995 to 2004 18 cases of lung cancer with TD were retrospectively reviewed in the Second Hospital Affiliated to China Medical University.Results Of the 18 cases,there were 7 cases complicated with deep venous thrombosis(DVT);3 cases with pulmonary thromboembolism(PTE);4 cases with DVT and PTE;4 cases with nonbacterial thrombotic endocarditis(NBTE).5 cases with DVT and(or)PTE occurred 2～6 months before detection of lung cancer,3 cases of NBTE had brain and peripheral artery embolism 2～7 months before detection of lung cancer.Conclusion TD could be warning a sign indicating advanced lung cancer.

Objective To explore the function and mechanism of Dihuang Yinzi (DHYZ) in promoting learning and memory and delaying brain aging. Methods The Wistar rats aged 20 months were randomly assigned to receive oral administration of 6, 12, 18 g?kg~ -1 ?d~ -1 DHYZ, or 2 ml/d normal saline (control) for 30 d (n=12 in each group), then space memory was detected with Morris Water Maze, and expression of synaptophysin (SYP) and extracellular regulated protein (ERK) were measured by immunohistochemistry and Western blotting. Results Rats administrated with DHYZ showed shorter mean escape latency (P

Periostin, a extracellular matrix protein structurally similar to fasciclin proteins, is expressed specifically in various tumor tissues and correlates with tumor progression and prognosis. Periostin prevents the apoptosis of tumor cells, promotes tumor growth and can induce angiogenic signaling cascades through αvβ3-FAK and Flk-1/KDR. It also contributes to epithelial-mesenchymal-transformation promoting tumor invasion and metastasis. Periostin maybe a potential therapeutic target of cancer treatment.