1.Clinical observation of hormone therapy after transerviacal resection of endometrial polyps
China Medical Equipment 2015;(6):94-96,97
Objective: To observe the efficiency of the therapy of hormone treatment aftertranscerviacal resection of endometrial polyps (TCRP). Methods: Eighty-six cases of endometrial polyps were analyzed retrospectively. They were divided into the control group (39 cases), which with simple TCRP, and the observation group (47 cases), which treated with hormone after TCRP. The clinical efficiency was compared between 2 groups. Results:The operation time of control group is 16-45 min, average (29.8±7.2) min; the intraoperative blood loss was 10-65ml, average(41.8±11.6) ml. The operation time of observation group was 18–55 min, average (33.2±8.8) min;the intraoperative blood loss was from 13–69 ml, average(43.2±13.1)ml. The differences of operation time and intraoperative blood loss between the two groups were not significant. The recurrence rate of observation group (6.38%) was much lower than control group(30.77%)(x2=8.802, P<0.05). 1 month, 3 months, 6 month and 1 year after therapy, the menstrual blood volume were (53.6±17.8)ml, (41.3±13.5)ml, (33.8±9.6)ml and (20.8±6.4)ml, respectively, which were much lower than the control group (t=12.564, t=12.691, t=14.494, t=23.72; P<0.05). 1 month, 3 months, 6 month and 1 year after therapy, the endometrial thickness were (8.2±1.0)mm, (7.1±0.9)mm, (4.2±0.8)mm and (3.5±0.7)mm, respectively, which were much lower than the control group (t=1.324, t=3.774, t=11.996, t=10.508; P<0.05). Conclusion: The menstrual blood volume, the endometrial thickness and the recurrence of endometrial polyps can be effectively reduced with the hormone therapy after TCRP.
2.The chinical dependablities between type 2 diabetes and lung cancer
Chinese Journal of Practical Internal Medicine 2003;0(01):-
Objective To analyze the association between type 2 diabetes and lung cancer and study their clinical features.Methods 76 lung cancer patients admitted in Shengjing hospital from June 2006 to June 2008 and their neighbors(or their colleagues)were enrolled to conduct a 1∶1 matched case control study.Results 27.63% of lung cancer patients had type 2 diabetes.Adenocarcinoma was the most common type associated with type 2 diabetes,accounting for 47.62%.There was no statistical significance in ages and gender between cases and their matched control.The symptoms of type 2 diabetes with lung cancers were not typical.Conclusion Type 2 diabetes is significantly correlated with lung cancers.The incidence of type 2 diabetes in lung cancer patients is higher than that in subjects without lung cancers.Early diagnosis and strict blood glucose control are critical for good prognosis.
3.MORpHOLOGY AND SPROUTING OF MOTOR NERVE TERMINALS IN CAT: DIFFERENCES BETWEEN FAST AND SLOW MUSCLES
Acta Anatomica Sinica 1955;0(03):-
Motor nerve terminals of fast muscles (lateral head of gastrocnemius, l. g. medial head of gastrocnemius, m. g.) and slow muscles (soleus, sol.) in 4 healthy adult cats were studied in teased muscle fibres with zinc iodide-osmium tetroxide (ZIO) staining. The motor nerve terminals stained with ZIO had a more delicate appearnance than those stained with other methods. It was obvious that fairly marked differences between the strutures of fast and slow muscle end-plate in cat. The terminal sprouts were also different between fast and slow muscle motor nerve terminals. in cat. The percentages of preterminal sprout were mean%?S.D. 8.5?5.4, 7.1?3.2 and 0.3?0.5 in l. g., m. g, and sol. respectively, and the percentages of ultraterminal sprout were 0, 0.3?0.5 and 5.7?2.0 in l. g., m. g. and sol. respectively. In each l. g., m. g. or sol. muscle, not only the size and complexity of end-plates were different, but also there were various kinds of end-plates. All of these showed the different stages of growth, sprouting, degeneration and replacement. The turnover of motor nerve terminal and the factors which influence the morphology of the end-plates in normal adult cat are discussed.
4.Diagnostic value of ultrasound for fetal heart malformation during 11-13+6 weeks gestation
Chinese Journal of Primary Medicine and Pharmacy 2017;24(11):1635-1638
Objective To investigate the value of ultrasound in diagnosis of fetal heart malformation at 11-13+6 weeks gestation.Methods A total of 70 pregnant women were selected,based on the results of induction of labor and postnatal imaging examination, the effect of ultrasound on fetal heart abnormalities in 11-13+6 weeks was observed.The display of cardiac malformations with different cuts was compared.Results In 70 fetuses with cardiac malformations, malformation types included tetralogy of Fallot, double outlet right ventricle, complete endocardial cushion defect, transposition of the great arteries, persistent truncus arteriosus, aortic arch, venous drainage.Ultrasound diagnosis of 64 cases of fetal cardiac malformations, the diagnostic accuracy rate was 91.4%.Among them, the highest proportion of tetralogy of Fallot (42.9%), venous drainage was the lowest (2.9%).The diagnostic rate of 4CV+3VVT ultrasound for fetal heart malformation was the highest(91.4%), which was significantly higher than 4CV+VOTV(72.2%), 4CV+(AR-SAV)(68.6%) and 4CV, the differences were statistically significant (x2=7.643,5.324,4.447,all P<0.05).The diagnostic accuracy of 4CV+3VV ultrasound for fetal heart malformation was 88.6%, which was significantly higher than 4CV+ (AR-SAV) and 4CV section, the differences were statistically significant (x2=6.343,4.011,all P<0.05).Conclusion Ultrasound can be used to detect fetal heart malformation at 11-13+6 weeks gestation, among them, the accuracy of 4CV+3VVT ultrasound section is the highest.
7. Protective effects of 3, 4-di-O-methyl-1,2,5,6-D-Mannitol tetranitrate on myocardial ischemia induced by ligating coronary artery in rats
Chinese Pharmaceutical Journal 2012;47(3):190-193
OBJECTIVE: To study the effects of 3, 4-di-O-methyl-1, 2, 5, 6-D-mannitol tetranitrate(DMMTN) on acute myocardial ischemia induced by ligating coronary artery in rats. METHODS: Acute myocardial ischemia model was developed by ligating the anterior descending branch of left coronary artery in rats. The rats were randomly divided into 6 groups: sham group, model group, Lunanxinkang group, low-dose (15 mg · kg-1) DMMTN group, middle-dose (30 mg · kg-1) DMMTN group and high-dose (60 mg · kg-1) DMMTN group. The changes of ST segment and T segment of electrocardiogram at different moment were recorded after myocardial ischemia injury. At 3 h after ligation, the myocardial infarct size was measured by nitroblue tetrazolium (NBT) staining method. And the activities of creatine phosphokinase (CK), lactate dehydrogenase (LDH) and superoxide dismutase (SOD), and the content of malondialdehyde (MDA) were determined to evaluate the protective effects of DMMTN. RESULTS: DMMTN could reduce the size of myocardial infarct significantly, inhibit the rising of ST segment and T segment of electrocardiogram, decrease the level of CK, LDH and MDA, and increase the activity of SOD. CONCLUSION: DMMTN showed obvious protective effects on acute myocardial ischemia induced by ligating the coronary artery in rats. Copyright 2012 by the Chinese Pharmaceutical Association.
8.Diagnostic value of echocardiography in myocardial infarction and its complications
Tian TIAN ; Zhaopeng XIE ; Zhuo CHEN ; Rong ZHAO
Chongqing Medicine 2017;46(17):2356-2358
Objective To study the value of echocardiography in the diagnosis of myocardial infarction(MI) and its complica tions.Methods The examination data in 140 cases of MI were collected from January 2012 to January 2016 and performed the analysis and comparison.Results In the ultrasound examination results in 140 cases,120 cases appeared varying degrees of segmental ventricular wall motion abnormalities,its diagnostic rate to MI was 85.71%,which of EKG was 78.57%,the MI detection rate of echocardiography and ECG combined examination was 90.71%,which was higher than that of single use of echocardiography or ECG.With the coronary angiogra-phy results as the control,the detection rate of echocardiography for the coronary arterial lesion sits was 82.86 %.Among 140 cases of MI,22 cases of complications(15.71 %) were de-tected out by echocardiography,including 7 cases of true ventricular aneurysm(5.00 %),4 cases of left ventricular mural thrombosis(2.86 %),1 case of ventricular septal perforation(0.71%) and 10 cases of ischemic mitral regurgitation(7.14%).Conclusion Echocardiography has higher accuracy in the MI diagnosis,com-bining with ECG can further improve the diagnostic rate.
9.Biomechanical analysis of the deep radioulnar ligaments stabilizing the distal radioulnar joint
Yanbo RONG ; Guanglei TIAN ; Shanlin CHEN
Journal of Peking University(Health Sciences) 2017;49(3):518-521
Objective: To evaluate the role of the deep radioulnar ligament in the stability of the distal radioulnar joint (DRUJ).Methods: In the study, 14 fresh cadaver upper extremities were randomly divided into two groups.After exposuring the palmar and dorsal deep distal radioulnar ligament, one group was marked as palmar deep radioulnar ligament, and the other group was marked as dorsal deep radioulnar ligament.The pronator teres and the supinator were exposed.A Kirschner wire perpendicular to the bone on Lister tubercle of radius was inserted, then another Kirschner wire on the same level of ulnar inserted when the forearm was in neural position, which was kept parallel to the first Kirschner wire.These specimens were mounted on a specially designed jig which held the limb rigidly, keeping the elbow fle-xion and the ulnar fixation.The radius could freely rotate around the ulnar.Then 50 N force on the pronator teres was applied to simulate the active pronation, and 60 N force on the supinator to simulate the active supination.The active pronation was stimulated, and the displacement of the distal radius was measured with respect to the ulna.The active supination was atimulated, and the displacement of the distal radius was measured with respect to the ulna.The palmar deep radioulnar ligament in one group was cut, then the displacement of the distal radius measured with respect to the ulna when the forearm was in pronation and supination.The dorsal deep radioulnar ligament in the other group was cut, and the displacement of the distal radius measured with respect to the ulna when the forearm was in pronation and supination.Results: After resection of the palmar deep radioulnar ligament, the displacement of the distal radius with respect to the ulna was statistically significantly different when the forearm was in pronation (t=5.591, P=0.001), but there was no difference when the forearm was in supination (t=0.433, P=0.680).After resection of the dorsal deep radioulnar ligament, the displacement of the distal radius with respect to the ulna was not different when the forearm was in pronation (t=1.000, P=0.356), but there was statistically significant difference when the forearm was in supination (t=6.225, P=0.001).Conclusion: DRUJ is unstable when the forearm is in pronation after resection of the palmar deep ra-dioulnar ligament, and DRUJ is unstable when the forearm is in supination after resection of the dorsal deep radioulnar ligament.
10.The Advance of Comorbidity of Metabolic Syndrome and Psychiatric Disease
Rong LUO ; Xinyi LIU ; Fengshi TIAN
Tianjin Medical Journal 2014;(2):188-191
The frequent co-occurrence of metabolic syndrome (MS) and mental disorders has become increasingly common, which is known clinically as comorbidity. Epidemiological survey showed that schizophrenia and mood disorders are the most common co-existing psychiatric disorders of metabolic syndrome. The pathogenesis of comorbidity of mental dis-orders and MS is related with hypothalamic-pituitary-adrenal axis dysfunction, unhealthy lifestyles and related applications of antipsychotics. An important reason for the metabolic syndrome associated with schizophrenia is heredity. However, in-flammation is the key factor in the relationship of mood disorders and MS. The intervention of unhealthy lifestyle, psychologi-cal counseling and rational use of drug should all be included in the treatment of comorbidity of psychiatric disorders and MS. The follow-up of metabolic index in psychiatric patients and psychological conditions in patients of MS should be paid more attention during the whole course of treatment.