1.Vertical and horizontal one and a half syndrome with ipsiversive ocular tilt reaction in unilateral rostral mesencephalic infarct: A rare entity
Rohan Mahale ; Anish Mehta ; Kiran Buddaraju ; Srinivasa Rangasetty
Neurology Asia 2015;20(4):413-415
Supranuclear ocular movements comprise mainly vertical and horizontal movements. Vertical movements
are controlled by the centres located mainly at the rostral midbrain and horizontal movements at the level
of the pons.1
Pontine tegmental lesions usually present with gaze palsies, internuclear ophthalmoplegia
(INO), abducens palsy and one and a half syndrome. Usually, one and a half syndrome is produced by
a unilateral caudal pontine tegmental lesion that includes the paramedian pontine reticular formation
(PPRF) and medial longitudinal fasciculus (MLF) on the same side causing horizontal gaze palsy
in one eye and INO in the other eye.2
Similarly, vertical one and a half syndrome has also been
described. The literature on co-existence of horizontal and vertical one and a half syndrome is few.
The co-existence of horizontal and vertical one and a half syndrome with ocular tilt reaction (OTR)
has not been reported so far. Here, we report a patient who presented with left horizontal one and a
half syndrome along with bilateral conjugate upgaze palsy and right downward palsy suggestive of
vertical one and a half syndrome and left ocular tilt reaction. Magnetic resonance imaging (MRI)
brain revealed infarct in left rostral midbrain with sparing of pons
Eye Infections
2.Establishing the Law of Parsimony in a Case of Restless Legs Syndrome
Shreyashi JHA ; Santosh Kumar PENDYALA ; Rohan Ramachandra MAHALE
Journal of Sleep Medicine 2024;21(1):51-53
Restless legs syndrome (RLS) is a common movement disorder characterized by uncomfortable sensations in the lower limbs relieved by limb movements. Clinical studies have established a possible association between RLS and vitamin B12 deficiency but not a causal one. RLS has rarely been reported as an isolated neurological manifestation of vitamin B12 deficiency. In this case report, we described a 24-year-old young man with RLS who responded poorly to symptomatic therapy. The etiological evaluation suggested vitamin B12 deficiency secondary to pernicious anemia. The patient responded rapidly to vitamin B12 supplementation and clinical manifestations of RLS resolved, suggesting a possible causal relationship.
3.Establishing the Law of Parsimony in a Case of Restless Legs Syndrome
Shreyashi JHA ; Santosh Kumar PENDYALA ; Rohan Ramachandra MAHALE
Journal of Sleep Medicine 2024;21(1):51-53
Restless legs syndrome (RLS) is a common movement disorder characterized by uncomfortable sensations in the lower limbs relieved by limb movements. Clinical studies have established a possible association between RLS and vitamin B12 deficiency but not a causal one. RLS has rarely been reported as an isolated neurological manifestation of vitamin B12 deficiency. In this case report, we described a 24-year-old young man with RLS who responded poorly to symptomatic therapy. The etiological evaluation suggested vitamin B12 deficiency secondary to pernicious anemia. The patient responded rapidly to vitamin B12 supplementation and clinical manifestations of RLS resolved, suggesting a possible causal relationship.
4.Establishing the Law of Parsimony in a Case of Restless Legs Syndrome
Shreyashi JHA ; Santosh Kumar PENDYALA ; Rohan Ramachandra MAHALE
Journal of Sleep Medicine 2024;21(1):51-53
Restless legs syndrome (RLS) is a common movement disorder characterized by uncomfortable sensations in the lower limbs relieved by limb movements. Clinical studies have established a possible association between RLS and vitamin B12 deficiency but not a causal one. RLS has rarely been reported as an isolated neurological manifestation of vitamin B12 deficiency. In this case report, we described a 24-year-old young man with RLS who responded poorly to symptomatic therapy. The etiological evaluation suggested vitamin B12 deficiency secondary to pernicious anemia. The patient responded rapidly to vitamin B12 supplementation and clinical manifestations of RLS resolved, suggesting a possible causal relationship.
5.A Case of Bilateral Occipital Lobe Infarcts Following Indian Tree Viper Bite.
Rohan MAHALE ; Anish MEHTA ; Mahendra JAVALI ; R SRINIVASA
Journal of Stroke 2014;16(3):205-207
No abstract available.
Occipital Lobe*
6.A Case of Bilateral Occipital Lobe Infarcts Following Indian Tree Viper Bite.
Rohan MAHALE ; Anish MEHTA ; Mahendra JAVALI ; R SRINIVASA
Journal of Stroke 2014;16(3):205-207
No abstract available.
Occipital Lobe*
7.Extraparenchymal (Racemose) Neurocysticercosis and Its Multitude Manifestations: A Comprehensive Review.
Rohan R MAHALE ; Anish MEHTA ; Srinivasa RANGASETTY
Journal of Clinical Neurology 2015;11(3):203-211
Neurocysticercosis is an infection of the central nervous system caused by the larval form of the pork tapeworm Taenia solium. In the brain it occurs in two forms: parenchymal and extraparenchymal or racemose cysts. The clinical presentation of racemose cysts is pleomorphic, and is quite different from parenchymal cysticercosis. The clinical diagnosis of racemose cysts is quite challenging, with neuroimaging being the mainstay. However, the advent of newer brain imaging modalities has made a more accurate diagnosis possible. The primary focus of this article is racemose neurocysticercosis and its multitude manifestations, and includes a discussion of the newer diagnostic modalities and treatment options.
Brain
;
Central Nervous System
;
Cysticercosis
;
Diagnosis
;
Neurocysticercosis*
;
Neuroimaging
;
Taenia solium
8.Malignant Cerebral Venous Sinus Thrombosis in Polycythemia.
Rohan MAHALE ; Anish MEHTA ; Kiran BUDDARAJU ; Abhinandan K SHANKAR ; Srinivasa RANGASETTY
Journal of Stroke 2015;17(3):362-365
No abstract available.
Polycythemia*
;
Sinus Thrombosis, Intracranial*
9.Patient Knowledge, Attitude and Perceptions towards Botulinum Toxin Treatment for Movement Disorders in India
Thavasimuthu Nisha MOL ; Nitish KAMBLE ; Vikram V. HOLLA ; Rohan MAHALE ; Pramod Kumar PAL ; Ravi YADAV
Journal of Movement Disorders 2021;14(2):126-132
Objective:
There is limited literature on the knowledge, attitude, and perceptions (KAP) of botulinum toxin (BoNT) treatment among patients and caregivers. The objective of this study was to assess the KAP in patients undergoing BoNT treatment for movement disorders.
Methods:
One hundred patients with movement disorders from National Institute of Mental Health and Neurosciences Hospital in Bengaluru, South India, were recruited. The patients underwent demographic, clinical, and Patient Knowledge Questionnaire on Botulinum Toxin Use in Movement Disorders (PKQ-BMD)-based evaluations.
Results:
The mean age of patients at the time of presentation was 47.97 ± 14.19 years (range, 12–79). Of all the patients, 26 (28%) patients were anxious, and 86% of these patients were reassured after appropriate counseling. There were 83 (89%) patients who found BoNT to be a costlier option. Education and previous Internet searches influenced positive performance in the “knowledge” domain and overall PKQ-BMD scores. The “number of injections” was also positively correlated with KAP performance.
Conclusion
This study showed that knowledge and perceptions about BoNT treatment need to be further improved. Wider availability of the Internet has provided a positive impact on patients’ and carers’ KAP. Internet-based information, higher educational qualifications of the patients, and a higher number of BoNT injection sessions are the most important predictors of satisfactory KAP related to BoNT injection treatment in patients with movement disorders.
10.Patient Knowledge, Attitude and Perceptions towards Botulinum Toxin Treatment for Movement Disorders in India
Thavasimuthu Nisha MOL ; Nitish KAMBLE ; Vikram V. HOLLA ; Rohan MAHALE ; Pramod Kumar PAL ; Ravi YADAV
Journal of Movement Disorders 2021;14(2):126-132
Objective:
There is limited literature on the knowledge, attitude, and perceptions (KAP) of botulinum toxin (BoNT) treatment among patients and caregivers. The objective of this study was to assess the KAP in patients undergoing BoNT treatment for movement disorders.
Methods:
One hundred patients with movement disorders from National Institute of Mental Health and Neurosciences Hospital in Bengaluru, South India, were recruited. The patients underwent demographic, clinical, and Patient Knowledge Questionnaire on Botulinum Toxin Use in Movement Disorders (PKQ-BMD)-based evaluations.
Results:
The mean age of patients at the time of presentation was 47.97 ± 14.19 years (range, 12–79). Of all the patients, 26 (28%) patients were anxious, and 86% of these patients were reassured after appropriate counseling. There were 83 (89%) patients who found BoNT to be a costlier option. Education and previous Internet searches influenced positive performance in the “knowledge” domain and overall PKQ-BMD scores. The “number of injections” was also positively correlated with KAP performance.
Conclusion
This study showed that knowledge and perceptions about BoNT treatment need to be further improved. Wider availability of the Internet has provided a positive impact on patients’ and carers’ KAP. Internet-based information, higher educational qualifications of the patients, and a higher number of BoNT injection sessions are the most important predictors of satisfactory KAP related to BoNT injection treatment in patients with movement disorders.