Objective: This study assessed the effectiveness and safety of resistance training in prostate cancer patients receiving androgen deprivation therapy (ADT).
Methods: Ten patients in the absence of metastasis undertook a 20-week progressive resistance training (2 times/week) consisting of 12 different upper and lower body exercises using training machines. Body composition, muscle function, physical performance, bone mineral density, serum biochemical data, plasma insulin and blood markers of prostate cancer were assessed at baseline and after training at weeks 10 and 20.
Results: Training significantly increased muscle strength and muscle endurance capacity (p<0.001) and decreased plasma insulin levels without affecting blood markers of prostate cancer.
Conclusion: Results suggest that resistance training is beneficial for prostate cancer patients with ADT to reduce the side effects of ADT and improve the activity of daily living and quality of life.

The use of isokinetic dynamometry has often been criticised based on the face-validity argument that isokinetic movements poorly resemble the everyday multi-segmented, dynamic activities of human movements. In the anterior cruciate ligament (ACL) reconstruction or deficiency population where muscle deficits are ubiquitous, this review paper has made a case for using isokinetic dynamometry to isolate and quantify these deficits in a safe and controlled manner. More importantly, the usefulness of isokinetic dynamometry, as applied in individuals with ACL reconstruction or deficiency, is attested by its established known-group and convergent validity. Known-group validity is demonstrated by the extent to which a given isokinetic measure is able to identify individuals who could and could not resume pre-morbid athletic or strenuous activities with minimal functional limitations following an ACL injury. Convergent validity is demonstrated by the extent to which a given isokinetic measure closely associates with self-report measures of knee function in individuals with ACL reconstruction. A basic understanding of the measurement properties of isokinetic dynamometry will guide the clinicians in providing reasoned interventions and advancing the clinical care of their clients.
Adolescent ; Adult ; Anterior Cruciate Ligament ; physiopathology ; surgery ; Anterior Cruciate Ligament Injuries ; Biomechanical Phenomena ; Female ; Humans ; Knee Injuries ; physiopathology ; surgery ; Male ; Middle Aged ; Muscle Contraction ; physiology ; Orthopedic Procedures ; Range of Motion, Articular ; physiology ; Torque