Objective:To explore the cytotoxic activity of the alcoholic extracts of some medicinal plants used traditionally to treat cancer in Chhattisgarh state, India. Methods:In-vitro cytotoxicity of alcoholic extracts of five plants i.e. Artocarpus heterophyllus, Alangium salvifolium, Buchanania lanzan, Sesbania grandiflora and Wrightia tinctoria was studied against human breast cancer (MCF-7) and human leukemia (HL-60) tumor cell lines, using the thiazolyl blue test (MTT) assay. Results: Alcoholic extract of Sesbania grandiflora exhibited a prominent inhibitory effect against MCF-7 (IC50 7.00±0.08μg/mL) and HL-60 (IC50 18.50±0.60μg/mL) under in vitro condition. Conclusions:From the result it can be found that the Sesbania grandiflora extract has potent in vitro cytotoxic activity.

Objective: To evaluate the antibacterial activity of the petroleum ether extract of root of Buteamonosperma B. monosperma was studied against Staphylococcus faecalis (S. faecalis), Sterptococcus faecalis (S. faecalis), Aeromonas hydrophilia (A. hydrophilia), Salmonela typhae (S. typhae), Stphylococcus cohni (S. cohni), Escherichia coli (E. coli) and Serratia ficaria (S. ficaria) by using well diffusion method. Results: Petroleum ether extract of root of B. monosperma exhibited a prominent inhibitory effect against bacterial strains. Conclusion: From the result it can be concluded that the B. monosperma extract has potent in vitro antibacterial activity. (B. monosperma). Method: In vitro antibacterial activity of petroleum ether i.e.

We performed bibliometric analysis of the research papers published on clinical cervical spondylotic myelopathy (CSM) in the last 50 years. We extracted bibliometric data from Scopus and PubMed from 1970 to 2020 pertaining to clinical studies of CSM. The predominant journals, top cited articles, authors, and countries were identified using performance analysis. Science mapping was also performed to reveal the emerging trends, and conceptual and social structures of the authors and countries. Bibliometrix R-package was deployed for the study. The total numbers of clinical studies available in PubMed and Scopus were 1,302 and 3,470, respectively. The most cited article was published by Hilibrand AS, as observed in Scopus. Regarding the conceptual structure of the research, two main research themes were identified, one involving symptomatology, scientific-scale-based objective evaluation of symptoms, and surgical removal of the offending culprit, while the other was based on patho-etiology, relevant diagnostic modalities, and the surgery commonly performed for CSM. In terms of emerging trends, in recent times there is an increasing trend of scale-based objective evaluations, along with investigations of advanced nonoperative management. The United States is the most productive country, whereas Canada tops the list for inter-country collaboration. The trend of research showed a shift toward noninvasive procedures.

Fine needle aspiration (FNA) of the thyroid is a well-tolerated minimally invasive procedure. Thyroid abscess, as a complication of FNA in an immune-competent adult, is extremely rare. Diagnosis requires a high index of suspicion, for which treatment is intravenous antibiotics, drainage, and sometimes surgery. Here we present a case of thyroid abscess in an otherwise healthy man who presented with neck pain, rapidly increasing neck swelling, difficulty in swallowing, and hoarseness of the voice that developed two weeks after diagnostic FNA of a thyroid nodule which had been present for ten months. Despite antibiotic treatment, the abscess ruptured into the trachea, requiring surgical intervention. This highlights the importance of maintaining asepsis during FNA of the thyroid. Timely diagnosis of a thyroid abscess is essential to avoid life-threatening airway complications.