The first local case of a 37 year old Gravida 5 Para 3 (2-1-2-3) with adrenocortical carcinoma who developed metastases during pregnancy is reported. Patient initially presented with signs and symptoms of Cushings and virilization. Ultrasound revealed a solid suprarenal mass. Biochemical evaluation showed increased levels of urinary cortisol, 17-ketosteroids, serum testosterone and serum DHEA-S. Adrenalectomy revealed adrenocortical carcinoma. Complications developed at 31 weeks AOG necessitating early termination of pregnancy. In the absence of a more effective treatment modality, chemotherapy was started obtaining optimum outcome for both the mother and the fetus.
Human ; Female ; Adult ; ADRENAL GLAND NEOPLASMS ; PREGNANCY

A 31 year old Filipino male diagnosed with obstructive azoospermia underwent TESE. Other current advanced sperm retrieval techniques include MESA, PESA and TESA confounded with female factors such as advanced maternal age and polycystic ovaries, IVF-ICSI eventually resulted to a successful pregnacy outcome. Several factors contributing to the success of IVF-ICSI eventually resulted to a successful pregnancy outcome. Several factors contributing to the success of IVF-ICSI in this case were also discussed. Although assisted reproductive technology is relatively new in our country, it proved to be promising in our local setting.
Human ; Female ; Adult ; REPRODUCTIVE TECHNIQUES, ASSISTED ; AZOOSPERMIA ; SPERM RETRIEVAL