Child ; Cough ; complications ; therapy ; Humans ; Rhinitis, Allergic, Perennial ; complications ; therapy

Asthma ; complications ; therapy ; Child ; Humans ; Rhinitis, Allergic, Perennial ; complications ; therapy

OBJECTIVETo investigate the relationship between the different types of allergic rhinitis and anxiety.

METHODSState-trait anxiety (State-Trait Anxiety Inventory, STAI) was adopted to 98 cases, moderate to severe persistent allergic rhinitis (PAR, male 43 cases, female 55 cases ) and 165 cases of moderate to severe intermittent allergic rhinitis (IAR, male 89 cases, female 76 cases ) and compared with the Chinese standard norm.SPSS 15.0 software was used to analyze the data.

RESULTSThere was no significant difference in state anxiety (S-AI) and trait anxiety (T-AI) score (P(PAR): 0.411,0.724; P(IAR): 0.400,0.061) between male patients with allergic rhinitis (PAR and IAR) and the 1998 Chinese male norm. There was no significant difference (P(PAR): 0.503, P(IAR): 0.789) between female AR patients and normal in T-AI. The S-AI score was significantly higher in female AR patients than that in Chinese women norm scores (P(PAR) = 0.007, P(IAR) = 0.004). PAR and IAR showed no significant difference on T-AI and S-AI. (P value was 0.748 and 0.967).

CONCLUSIONSFemale patients with allergic rhinitis can cause anxiety and continued, but there is no obvious anxiety potential in T-AI. The male patients do not show significantly different from normal people in terms of state and trait anxiety. And then, different types of allergic rhinitis have no significant correlation with anxiety.

Chronic Disease ; Humans ; Nasal Polyps/complications* ; Rhinitis/complications* ; Rhinitis, Allergic ; Sinusitis/complications* ; Staphylococcal Infections/complications* ; Staphylococcus aureus

Deafness ; complications ; Humans ; Middle Aged ; Osteochondrodysplasias ; complications ; Rhinitis ; complications ; Sinusitis ; complications

The datas of epidemiological, clinical, and immunopathology demonstrate there is an important link between upper and lower airways. The upper airways diseases including the allergy rhinitis, the professional rhinitis, the sleep apnea and hypoventilation syndrome, nose polyposis (with/without aspirin sensitive), the chronic rhinosinusitis and so on, have an important contacting with lower airways diseases. Understanding how the upper airway does affect the lower airway disease, has the influential role to diagnosis, the treatment and the prognosis. This article made the brief summary on the important relation about among the nose, the paranasal sinus and the lung recent years.
Asthma ; complications ; Humans ; Lung Diseases, Obstructive ; complications ; Rhinitis ; complications ; Sinusitis ; complications

Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma is a common clinical refractory airway disease. Comprehensive treatment of nasal endoscopic surgery including nasal endoscopic surgery and medication, which can significantly improve nose-pulmonary symptoms and make sinusitis and asthma easier to be controlled by medication, has certain superiority. But the existence of disease heterogeneity of CRSwNP with asthma causes different reactions to the current treatment, which manifests as parts of polyps and asthma easy to recur and difficult to control. According to the research recently, the study of the heterogeneity of airway diseases, for example endotype, is a hot area of research. Endotype is a subtype of a condition, which is defined by a distinct functional or pathobiological mechanism. This is distinct from a phenotype, which is any observable characteristic or trait of a disease. Different Inflammatory subtypes often represent different pathophysiology and even different pathogenesis. The concept of inflammatory subtypes of airway diseases provides a new perspective for studies of airway diseases of endotype and the mechanism of combined airway diseases. This review summarizes recent advances in the clinical characterization and treatment of the CRSwNP with asthma. On this basis, we analyze and summarize the heterogeneity of CRSwNP and asthma separately from the perspective of inflammatory subtypes. Then according to the concept of the combined airway diseases and the common pathogenesis, we put forward the definition of inflammatory subtypes of the CRSwNP with asthma and preliminarily discuss the method of the definition.
Asthma ; complications ; Chronic Disease ; Endoscopy ; Humans ; Nasal Polyps ; complications ; Rhinitis ; complications ; diagnosis ; Sinusitis ; complications ; diagnosis

Objective:To investigate the effect of posterior nasal neurectomy（PNN） with pharyngeal neurectomy （PN） on chronic sinusitis with nasal polyps （CRSwNP）complicated with perennial allergic rhinitis （PAR）. Methods:83 patients with perennial allergic rhinitis combined with chronic group-wide sinusitis with nasal polyps who attended our hospital from July 2020 to July 2021 were selected. All patients underwent conventional functional endoscopic sinusitis surgery（FESS）+ nasal polypectomy. Patients were divided according to whether they underwent PNN+PN. 38 cases in the experimental group underwent FESS combined with PNN+PN; 44 cases in the control group underwent conventional FESS alone. All patients underwent the VAS, RQLQ, and MLK before treatment, and at 6 months and 1 year after surgery. Meanwhile, other relevant data were collected and the preoperative and postoperative follow-up data were collected and analyzed to assess the differences between the two groups. Results:The total postoperative follow-up period was 1 year. The recurrence rate of nasal polyps at 1 year postoperatively and the nasal congestion VAS score at 6 months postoperatively were not statistically significant in the two groups（P>0.05）. However, the patients in the experimental group had statistically significantly lower effusion and sneezing VAS scores, MLK endoscopy scores and RQLQ scores at 6 months and 1 year postoperatively, and nasal congestion VAS scores at 1 year postoperatively compared to the control group（P<0.05）. Conclusion:For patients with perennial AR complicated with CRSwNP, the combination of the PNN+PN in FESS can significantly improve the short-term curative effect, and PNN+PN is a safe and effective surgical treatment.
Humans ; Nasal Polyps/surgery* ; Rhinitis, Allergic/surgery* ; Sinusitis/surgery* ; Rhinitis, Allergic, Perennial ; Endoscopy ; Denervation ; Chronic Disease ; Rhinitis/complications*

Asthma ; Child ; Cough ; Humans ; Rhinitis, Allergic, Perennial ; complications ; diagnosis ; therapy

Biological Products ; Chronic Disease ; Humans ; Nasal Polyps/complications* ; Rhinitis/complications* ; Sinusitis/complications*