Asthma ; epidemiology ; Humans ; Rhinitis, Allergic ; Rhinitis, Allergic, Perennial ; epidemiology

554 pupils of Le Hong Phong primary school in Ngo Quyen district . Hai Phong city were enrolled in an investigation performed following the 25B from WHO concerning allergic diseases. Results were processing biostatistically. The prevalence is 37,32% in pupils, it is higher in girl than in boys. This prevalence increased progressively after 15 years old. The commonest conditions are respiratory allery, broncho-asthma 6.25%, allegic shinite-simusite 19,67%, urticaria 6,69, allergic reaction to medicaments 0,92%, to food 2,75%, to chemicals 0,97%, eczema 0,92%. Cold weather 33,64% and the change of weather 21,50% play important role in causing clinical symptom of allergic rhinite-simusite. In addition there are 14,02% of allergic response due to dust
Hypersensitivity ; Disease ; Rhinitis, Allergic, Perennial ; epidemiology

Child ; China ; epidemiology ; Humans ; Rhinitis, Allergic, Perennial ; epidemiology

Child ; Humans ; Rhinitis, Allergic, Perennial ; diagnosis ; epidemiology ; therapy

OBJECTIVE: To understand the prevalence rate and the relativity of allergic rhinitis and recurring respiratory infection of preschool children in Shenzhen, and to investigate and analyse the prevalence rate, predisposing factor, allergen, therapy, turnover on allergic rhinitis and recurring respiratory infection of preschool children. METHOD: The ENT doctors examined the investigated children and recorded them, then delivered questionnaires to the children's parents and explained to them. The result was analyzed statistically. RESULT: The prevalence rate of allergic rhinitis of preschool children in Shenzhen was 20.1%, the prevalence rate of recurring respiratory infection was 13.7%, the prevalence rate (18.0%) of allergic rhinitis combined recurring respiratory infection was higher than that (7.80) of cases with non-allergic rhinitis combined recurring respiratory infection. The difference had a statistical significance (P < 0.05). CONCLUSION We initially understood the epidemiologic situation of allergic rhinitis and recurring respiratory infection of preschool children in Shenzhen, providing epidemiologic datas for the standardization of prevention and cure for allergic rhinitis.
Allergens ; Child, Preschool ; China ; epidemiology ; Humans ; Respiratory Tract Infections ; epidemiology ; Rhinitis, Allergic, Perennial ; epidemiology ; Rhinitis, Allergic, Seasonal ; epidemiology ; Surveys and Questionnaires

OBJECTIVETo explore the effects of genetic factors on the occurrence of allergic rhinitis (AR).

METHODSThe morbidity rate of AR was surveyed by multistage sampling among 95 300 individuals (23,825 families) in Natong region, Jiangsu province. And a genetic epidemiologic investigation on AR was carried out to estimate the segregation ratio and heritability (h2) of AR by the methods of Li-Mantel-Gart and Falconer respectively.

RESULTSThe morbidity rate of AR in Natong region was 1.20% (Male 1.21%, Female 1.18%, no statistical significance between them); By the data of the AR ancestry, the segregation ratio of AR in Nantong region was 0.078, significantly less than 0.25, and the genetic model belonged to polygenetics. The 1st, the 2nd, and the 3rd generation h2 of AR were (82.6 +/- 2.19)%, (80.8 +/- 2.93)%, (78.4 +/- 7.04)%. The h2 of AR was (81.86 +/- 1.70)%. In the ancestry of AR, the morbidity rate of the 1st generation with AR was 12.11%; the 2nd generation with AR was 5.12%; the 3rd generation with AR was 2.75%; and the morbidity rate of AR in general population was 1.20%.

CONCLUSIONSThe heredity in family with AR is obvious. Several genes plus the environmental factors may cause AR, which accords with the characteristics of the polygene heredity disease.

China ; epidemiology ; Female ; Humans ; Male ; Multifactorial Inheritance ; Prevalence ; Rhinitis, Allergic, Perennial ; epidemiology ; genetics ; Rhinitis, Allergic, Seasonal ; epidemiology ; genetics

OBJECTIVEThe aim of this study is to investigate the self-reported prevalence and other epidemiological characteristics of allergic rhinitis from 11 cities throughout the mainland of China.

METHODSTelephone interviews were conducted in the two main municipalities (Beijing, Shanghai) and eight capital cities (Changsha, Changchun, Hangzhou, Guangzhou, Nanjing, Shenyang, Wuhan, Urumqi and Xi'an) of main provinces throughout the mainland of China after sampling target phone numbers by the approach of random digital dialing (RDD) via computer.

RESULTSIn total, the survey had sampled 684 blocks of telephone numbers in 11 cities, and dialed 119 319 telephone numbers. Of the 38 203 respondents, 4253 subjects reported allergic rhinitis, while the other 33 950 were screened negative in the telephone interviews. The self-reported prevalence of allergic rhinitis was lowest in Xi'an (8.0%), and highest in Urumqi (21.4%), with Nanjing having intermediate value (11.5%). The gender-adjusted prevalence ranged from 8.5% in Xi'an to 21.3% in Urumqi, while the age-adjusted prevalence of self-reported allergic rhinitis ranged from 8.7% in Beijing to 24.1% in Urumqi.

CONCLUSIONSThe study demonstrates that the self-reported prevalence of allergic rhinitis in 11 cities throughout the mainland of China has wide variations, and the strategy of prevention for allergic rhinitis should be conducted according to the epidemic features of it.

China ; epidemiology ; Female ; Humans ; Male ; Prevalence ; Rhinitis, Allergic, Perennial ; epidemiology ; Rhinitis, Allergic, Seasonal ; epidemiology ; Self Report ; Surveys and Questionnaires

OBJECTIVE: To investigate the epidemic features of allergic rhinitis(AR)and correlative risk factors in Shihezi city, Xinjiang province, China. METHOD: A questionnaire survey on AR and airway diseases was conducted among 2 300 elementary school children in 12 schools, aged from 9 to 10 years old, from july 10 to 25, 2008 . in Shihezi city, Xinjiang province. Suspects of AR was identified by the survey, then they were recommended to specialist examinations for accurate diagnosis. Allergen skin tests were performed to explore the allergenic varieties of allergic rhinitis. Diagnosis criteria of AR were that of ARIA (Allergic rhinitis and its impact on asthma). RE-SULT: Two thousand two hundred and eleven questionnaires were returned. The response rate was 96.1% and 2205 questionnaires were available. The prevalence rate of AR in children aged from 9 to 10 was 12.56% (277/2 205) in Shihezi city. The difference of prevalence between female 13.76% (153/1112) and male 11. 34% (124/1093) was insignificant statistically(CHI2 = 2.924, P > 0. 05). The positive rate of the allergen skin test was 65. 3%. The most common allergen of allergic rhinitis were plants of the mugwort and house dust mite. According to the classification criteria of ARIA in 2001, of 155 children suffered from intermittent AR, 112 cases were mild and 43 cases were moderate-severe, while 122 suffered from persistent AR,110 cases were mild and 12 cases were moderate severe. 5.4% (15/277) patients with AR also had bronchial asthma. 25. 3% (70/277) of the children with AR had inherent predisposition. CONCLUSION The prevalence rate of AR in children aged from 9 to 10 in Shihezi city is 12.56%. Strategy of prevention and treatment of AR can be worked out according to the epidemical feature of AR.
Allergens ; analysis ; Child ; China ; epidemiology ; Female ; Humans ; Male ; Prevalence ; Rhinitis, Allergic, Perennial ; epidemiology ; Rhinitis, Allergic, Seasonal ; epidemiology ; Schools ; Skin Tests

OBJECTIVE: To explore the inhaled allergen distribution of children with allergic rhinitis in Guangzhou area and to analyze the relevant factors. METHOD: Six hundred and twenty-six cases children in Guangzhou region diagnosed with allergic rhinitis from January 2009 to December 2011 in our outpatient department were tested with skin prick test (SPT). Ten of standardized common inhaled allergens were analysed. The variety of allergens positive rate was calculated. And the gender, age, living environment,history of asthma, eczema, history and family history of clinical data were analyzed. RESULT: The positive rate of SPT was 84.82% (531/626). The dust mites(76.36%) and the house dust mite(72.84%) have the highest positive rate, then the positive rate of the dog hair (11.98%), cat hair (7.03%) and Blattella germanica (4.31%) was degressively. The positive rate was significantly correlated with family history, history of eczema and asthma. The positive rate was correlated with the gender, independent of the living environment. The intensity of the test has no significant correlation with gender, and was significantly correlated with other factors. The positive rate of SPT has significant difference in ages and the highest positive rate of SPT was in the 10-14 age group, the SPT rate was 93.8%. Three groups have significant differences in the positive rate of mite, dog hair and cat hair. CONCLUSION The main inhaled allergen in children with allergic rhinitis in Guangzhou area tested by SPT was mite, dog hair and cat hair, respectively. The different ages, living environment, family history, history of eczema and allergic rhinitis children with asthma were related with the pathogenesis and development of AR in childhood. Our results have the contribution to early diagnosis and intervention of children with allergic rhinitis in Guangzhou area.
Adolescent ; Allergens ; analysis ; immunology ; Child ; Child, Preschool ; China ; epidemiology ; Female ; Humans ; Male ; Rhinitis, Allergic ; Rhinitis, Allergic, Perennial ; epidemiology ; Skin Tests

Allergic rhinitis is the most common atopic disease in the world. However, pathogenic mechanisms of allergic rhinitis have not been fully understood. Mouse models of allergic rhinitis are a great tool that allows in vivo studies to be conducted in the state of an intact immune and respiratory system. This model system can provide many chances to find important signaling pathways and therapeutic target molecules in allergic rhinitis. To start research in allergic rhinitis with mouse, we have to make good and reliable models. Current mouse model is not perfect with many confounding variables and has some limitations to translate findings to the clinic directly. Optimal mouse model mimicking human allergic rhinitis will promise to unravel new horizon in the field of allergic rhinitis.
Animals ; Confounding Factors (Epidemiology) ; Humans ; Mice ; Respiratory System ; Rhinitis ; Rhinitis, Allergic, Perennial